A5015234011- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Helicobacter pylori-related gastroenterology studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Neonatal and Maternal Infections
- Diet, Metabolism, and Disease
- Neonatal Respiratory Health Research
- Diet and metabolism studies
- Sepsis Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Maternal and fetal healthcare
- Bariatric Surgery and Outcomes
- Eosinophilic Esophagitis
- Gut microbiota and health
- Blood properties and coagulation
- SARS-CoV-2 and COVID-19 Research
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- Cystic Fibrosis Research Advances
- Esophageal Cancer Research and Treatment
- Blood transfusion and management
- Poisoning and overdose treatments
- Virus-based gene therapy research
Aristotle University of Thessaloniki
2017-2024
Papageorgiou General Hospital
2017-2024
Pre-eclampsia (PE) is a placenta-mediated disease and remains major cause of maternal neonatal mortality morbidity. As PE develops, normal pregnancy’s hypercoagulable balance disrupted, leading to platelet hyperactivation, excessive pathological hypercoagulability, perturbed fibrinolysis. This narrative review aims summarize the current knowledge regarding hemostasis in compared with healthy gestation potential effects on hemostasis. Finally, it discuss assessments for pregnancies PE,...
Neonatal sepsis is frequently accompanied by coagulopathy and thrombocytopenia attributed to the cross-link between inflammation coagulation. However, sepsis-induced platelet function in septic preterm neonates remain be elucidated. In addition, there no robust evidence for a causal relationship bleeding with sepsis.This single-center prospective cohort study aimed assess during sepsis.We included 25 Gram-positive born at gestational age 24 + 1 34 3 studied comparison 30 healthy...
Although respiratory distress syndrome (RDS) constitutes a postnatal risk factor for bleeding and thromboembolic events in neonates, few studies have addressed this issue. We aimed to evaluate the hemostatic profile of neonates with RDS using rotational thromboelastometry (ROTEM).An observational study was conducted from November 2018 2020 NICU General Hospital Nikaia "Aghios Panteleimon". Preterm term hospitalized were included EXTEM (tissue factor-triggered extrinsic pathway), INTEM...
Mutations in adenosine triphosphate-binding cassette transporter A3 (ABCA3) (OMIM: 601615) gene constitute the most frequent genetic cause of severe neonatal respiratory distress syndrome (RDS) and interstitial lung disease (ILD) children. Interstitial children especially infants, contrast to adults, is more likely appear as a result developmental deficits or characterized by aberrations pulmonary surfactant homeostasis not responding exogenous administration. The underlying ABCA3 mutations...
Abstract Introduction The aim of our study was to establish reference ranges for neonatal coagulation and fibrinolysis parameters investigate their relationship with gestational age (GA) birth weight (BW). Methods A single‐centre prospective conducted in all healthy neonates born hospital during the period, excluding those maternal or disorders diseases that affect haemostasis. following were measured: fibrinogen, prothrombin time (PT), international normalized ratio (INR), activated partial...
Nonalcoholic fatty liver disease (NAFLD) was recently renamed to metabolic (dysfunction)-associated (MAFLD) better characterize its pathogenic origin. NAFLD represents, at least in western societies, a potential epidemic with raising prevalence. Its multifactorial pathogenesis is partially unraveled and till now there no approved pharmacotherapy for NAFLD. A plethora of various choices are investigated clinical trials, targeting an arsenal different pathways molecules. Since the...
The neonatal intensive care unit (NICU) population, especially low birth weight and critically ill neonates, is at risk of invasive Candida infections, which are associated with high mortality rates unfavorable long-term outcomes. timely initiation an appropriate antifungal treatment has been demonstrated to enhance the prognosis. Factors that should be considered in choice agent include causative strain, presence location deep tissue infection, previous use prophylaxis, implanted devices....
Abstract Objectives During pregnancy, severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection may intensify the gestational procoagulant state. Coronavirus disease 2019 (COVID-19) associated coagulopathy (CAC) constitutes an exacerbated immunothrombosis response. There is limited data regarding coagulation profile of SARS-CoV2-infected pregnant women, especially those with CAC, and effect on their offspring. This prospective study aimed to compare hemostatic women neonates...