Yaru Han

ORCID: 0000-0003-0471-0432
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About
Contact & Profiles
Research Areas
  • Hip and Femur Fractures
  • RNA regulation and disease
  • Cancer therapeutics and mechanisms
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Function and Risk Factors
  • Aerosol Filtration and Electrostatic Precipitation
  • Phytochemistry and biological activities of Ficus species
  • CAR-T cell therapy research
  • Nanoplatforms for cancer theranostics
  • High voltage insulation and dielectric phenomena
  • MicroRNA in disease regulation
  • Diagnosis and Treatment of Venous Diseases
  • Calcium signaling and nucleotide metabolism
  • Nanocluster Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Axon Guidance and Neuronal Signaling
  • Advanced Algorithms and Applications
  • Membrane Separation Technologies
  • Central Venous Catheters and Hemodialysis
  • Cyclone Separators and Fluid Dynamics
  • Electrospun Nanofibers in Biomedical Applications
  • Diet and metabolism studies
  • Computational Drug Discovery Methods
  • Energy Load and Power Forecasting
  • Gastrointestinal motility and disorders

Columbia University
2025

First Affiliated Hospital of Hebei Medical University
2021-2024

Jining Traditional Chinese Medicine Hospital
2024

Inner Mongolia Medical University
2023

Third Xiangya Hospital
2018-2022

Central South University
2018-2022

Hebei Medical University
2022

Peking Union Medical College Hospital
2022

Chinese Academy of Medical Sciences & Peking Union Medical College
2022

Nanjing Tech University
2022

Alzheimer's disease (AD) is a neurodegenerative disorder that affects approximately 35 million people worldwide, and diet has been reported to influence the prevalence/incidence of AD. Colorectal cancer among most common cancers in Western populations, correlation between constipation occurrence colorectal identified number studies, which show Westernized mutual risk factor. Constipation growing health problem, particularly middle-aged older adults. As gastrointestinal adults, 2-20% world...

10.3389/fnagi.2018.00176 article EN cc-by Frontiers in Aging Neuroscience 2018-09-28

Abstract We investigated that microRNA (miRNA)‐141 protects against epilepsy‐induced apoptosis and its reaction mechanism. The serum expression of miRNA‐141 in epilepsy model mice control volunteer was measured by quantitative reverse‐transcription polymerase chain reaction. found upregulated patients with epilepsy. Overexpression induced nerve cell apoptosis, suppressed proliferation, promoted caspase‐3/9, Bax p53 protein expression, reduced silent information regulator 1 (SIRT1) vitro...

10.1002/jcb.28216 article EN Journal of Cellular Biochemistry 2018-12-12

The use of immune checkpoint inhibitor (ICI) marked a revolutionary change in cancer treatment and opened new avenues for therapy, but ICI can also trigger immune-related adverse events (irAEs). Here, we investigated the publicly available US Food Drug Administration (FDA) Adverse Event Reporting System (FAERS) database to gain insight into possible association between inhibitors hypophysitis. Data on (AEs) due hypophysitisfor nivolumab, pembrolizumab, ipilimumab, atezolizumab were collected...

10.1097/md.0000000000037587 article EN cc-by-nc Medicine 2024-03-29

What Is Known and Objective. Novel coronavirus disease (COVID-19) is still ravaging globally since its first discovery in 2019. With the continuous emergence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) mutant strains, therapeutic entities are needed to be discovered. This study was explore SARS-CoV-2 inhibitors for COVID-19. Methods. Based on Lipinski’s rule 5, a small-scale “old” drug database (clinical drugs being used Ordos Central Hospital) established, silico...

10.1155/2023/9955105 article EN Journal of Clinical Pharmacy and Therapeutics 2023-10-09

Objective. To compare the clinical effects of modified above-knee and conventional surgery with stripping great saphenous vein varicose veins lower extremities. Methods. Clinical data patients a extremity from May 2016 to 2018 were collected. A retrospective study was conducted on receiving stripping. The baseline characteristics long-term follow-up compared between groups. Results. There no significant differences in two groups ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1">...

10.1155/2022/7730960 article EN Computational and Mathematical Methods in Medicine 2022-01-12

Abstract To explore potential inhibitors of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) for the treatment novel coronavirus disease (COVID-19), in silico screening 135 clinical drugs was performed targeting on 3-chymotrypsin-like protease (3CLpro, or M pro ). Six including anti-HIV drug (raltegravir), antibacterial (cefonicid, cefoperazone, minocycline), and antidiabetic (canaglifozin, glyburide) showed high binding affinities (≤ -8.5 kcal/mol) interesting conformations...

10.21203/rs.3.rs-1528733/v1 preprint EN cc-by Research Square (Research Square) 2022-04-18

<title>Abstract</title> The full text of this preprint has been withdrawn by the authors while they make corrections to work. Therefore, do not wish work be cited as a reference. Questions should directed corresponding author.

10.21203/rs.3.rs-1131517/v2 preprint EN cc-by Research Square (Research Square) 2024-06-21

As the core device in field of communication, filter is developing towards miniaturization and high frequency. In this paper, a new dual frequency based on step impedance resonator proposed. The resonant frequencies proposed stepped (SIR) are 2.4GHz 5.2GHz, isolation greater than 20dB.

10.1109/icocn53177.2021.9563816 article EN 2022 20th International Conference on Optical Communications and Networks (ICOCN) 2021-08-23

<title>Abstract</title> Background The aim of this study is to explore whether or what extent the metabolic syndrome (METs) and its components was associated with poor outcome in acute type A aortic dissection patients (ATAAD) after surgery. Methods This involved 353 ATAAD undergo Data on demographic clinical characteristics were collected. Subgroup analysis, mixed models regression score systems receiver-operating characteristic curves (ROC) analysis done. Results Overall, inpatients...

10.21203/rs.3.rs-1131517/v1 preprint EN cc-by Research Square (Research Square) 2021-12-13
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