A5103134774- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Functional Brain Connectivity Studies
- Atomic and Subatomic Physics Research
- Bone and Joint Diseases
- Ultrasound and Hyperthermia Applications
- Lung Cancer Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Multiple Sclerosis Research Studies
- Advanced NMR Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Cerebrovascular and Carotid Artery Diseases
- Cervical and Thoracic Myelopathy
- Teratomas and Epidermoid Cysts
- Optical measurement and interference techniques
- Cardiomyopathy and Myosin Studies
- Gastrointestinal motility and disorders
- NMR spectroscopy and applications
- Advanced Radiotherapy Techniques
- Model Reduction and Neural Networks
Siemens Healthcare (Germany)
2018-2022
Tokyo Health Care University
2016-2021
Siemens (Germany)
2002-2015
Medical Technologies (Czechia)
2002
Okayama University
1997
The purpose of this study was to explore the potential non-Gaussian diffusion and perfusion magnetic resonance imaging (MRI) using intravoxel incoherent motion (IVIM) MRI for diagnosis breast lesions.This included 26 women with lesions. Diffusion-weighted images were acquired 16 b values up 2500 s/mm analyzed a kurtosis model (apparent coefficient [ADC0] [K]) component IVIM (perfusion fraction [fIVIM] pseudodiffusion [D*]) component. Diagnostic performance parameters evaluated from receiver...
Macaque monkeys are an important animal model where invasive investigations can lead to a better understanding of the cortical organization primates including humans. However, tools and methods for noninvasive image acquisition (e.g. MRI RF coils pulse sequence protocols) data preprocessing have lagged behind those developed To resolve structural functional characteristics smaller macaque brain, high spatial, temporal, angular resolutions combined with signal-to-noise ratio required ensure...
Diffusion tensor imaging (DTI) and neurite orientation dispersion density (NODDI) are widely used models to infer microstructural features in the brain from diffusion-weighted MRI. Several studies have recently applied both increase sensitivity biological changes, however, it remains uncertain how these measures associated. Here we show that cortical distributions of DTI NODDI associated depending on choice b-value, a factor reflecting strength diffusion weighting gradient. We analyzed...
Psychiatric and neurological disorders are afflictions of the brain that can affect individuals throughout their lifespan. Many magnetic resonance imaging (MRI) studies have been conducted; however, imaging-based biomarkers not yet well established for diagnostic therapeutic use. This article describes an outline planned study, Brain/MINDS Beyond human MRI project (BMB-HBM, FY2018 ~ FY2023), which aims to establish clinically-relevant with multi-site harmonization by collecting data from...
To compare magnetization-prepared two rapid acquisition gradient echoes (MP2RAGE) imaging with conventional MPRAGE for deep gray matter (GM) segmentation, reproducibility, contrast ratio (CR) and contrast-to-noise (CNR), to evaluate reproducibility of T1 maps derived from MP2RAGE.MP2RAGE were conducted twice each 20 volunteers on a 3 Tesla MRI scanner. Images normalized segmented using SPM12 the DARTEL algorithm. Reproducibility segmentation was evaluated coefficients variation (COVs) GM...
Abstract Cortical areas have traditionally been defined by their distinctive layer cyto- and/or myelo- architecture using postmortem histology. Recent studies delineated many measuring overall cortical myelin content and its spatial gradients the T1w/T2w ratio MRI in living primates, including humans. While of areal transitions might benefit from profile this myelin-related contrast, a significant confound is Gibbs’ ringing artefact, which produces signal fluctuations resembling layers....
Abstract Mapping of MR fiber g-ratio, which is the ratio diameter axon to neuronal fiber, introduced in this article. We investigated volume fraction (AVF) and myelin (MVF) evaluate microstructural changes spinal cord patients with cervical spondylotic myelopathy (CSM) vivo , using atlas-based analysis. used diffusion MRI data acquired a new simultaneous multi-slice accelerated readout-segmented echo planar imaging sequence for analysis AVF calculation magnetization transfer saturation MVF...
To investigate age-related changes in T1 relaxation time deep gray matter structures healthy volunteers using magnetization-prepared 2 rapid acquisition gradient echoes (MP2RAGE).In all, 70 (aged 20-76, mean age 42.6 years) were scanned at 3T magnetic resonance imaging (MRI). A MP2RAGE sequence was employed to quantify times. After the spatial normalization of maps with diffeomorphic anatomical registration exponentiated Lie algebra algorithm, voxel-based regression analysis conducted. In...
Microstructure imaging by means of multidimensional diffusion encoding is increasingly applied in clinical research, with expectations that it yields a parameter better correlates disability than current methods based on single encoding. Under the assumption within voxel can be well described collection tensors, several parameters this tensor distribution derived, including mean size, variance sizes, orientational dispersion, and microscopic anisotropy. The information provided also enables...
We report two cases of pathologically proven intracranial epidermoid cysts. Both were scanned with diffusion-weighted imaging using pulsed gradient spin-echo (PGSE) and oscillating (OGSE; 50 Hz) prototype sequences diffusion times 47.3 ms 8.5 ms, respectively. The apparent coefficient measured by OGSE was higher than that PGSE, indicating the spatial restriction water in laminated keratin layers within cyst as demonstrated histopathology.
<h3>BACKGROUND AND PURPOSE:</h3> T1-weighted pointwise encoding time reduction with radial acquisition (PETRA) sequences require limited gradient activity and allow quiet scanning. We aimed to assess the usefulness of PETRA in pediatric brain imaging. <h3>MATERIALS METHODS:</h3> included consecutive patients who underwent both MPRAGE PETRA. The contrast-to-noise contrast ratios between WM GM were compared cerebellar WM, internal capsule, corpus callosum. degree myelination was rated by using...
It has been reported that leakage of intravenously administered gadolinium-based contrast agents (IV-GBCAs) into the cerebrospinal fluid (CSF) from cortical veins even in healthy subjects can be detected using a highly sensitive pulse sequence such as heavily T2-weighted 3D fluid-attenuated inversion recovery and 3D-real (IR). The purpose this study was to evaluate feasibility MR fingerprinting detect GBCA after IV-GBCA.Fourteen patients with suspected endolymphatic hydrops (EH) who received...
This study aimed to evaluate comprehensively; accuracy, repeatability and reproducibility of T1 T2 relaxation times measured by magnetic resonance fingerprinting using B1+-corrected fast imaging with steady-state precession (FISP-MRF).The International Society Magnetic Resonance in Medicine/National Institute Standards Technology (ISMRM/NIST) phantom was scanned for 100 days, six healthy volunteers 5 days a FISP-MRF prototype sequence. Accuracy evaluated on the comparing reference values...
To evaluate the feasibility for detection of slight contrast effects after intravenous administration single dose gadolinium-based agent (IV-SD-GBCA), time course GBCA distribution up to 24 h was examined in various fluid spaces and brain parenchyma using 3D-real IR imaging MR fingerprinting (MRF).Twenty-four patients with a suspicion endolymphatic hydrops were scanned at pre-administration 10 min, 4 post-IV-SD-GBCA. images MRF level internal auditory canal obtained. The signal intensity on...
We prospectively examined the variability of non-Gaussian diffusion magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) measurements with different numbers b-values excitations in normal breast tissue lesions. Thirteen volunteers fourteen patients lesions (seven malignant, eight benign; one patient had bilateral lesions) were recruited this prospective study (approved by Internal Review Board). Diffusion-weighted MRI was performed 16 (0–2500 s/mm2 number [NEX]) five...
Abstract Gamma‐aminobutyric acid (GABA) is the major inhibitory neurotransmitter in brain, and plays a key role brain development. However, vivo levels of GABA early life are unknown. Using edited MRS, can be detected as GABA+ signal with contamination macromolecule signals. evaluated peak ratio GABA+/reference compound, for which creatine (Cr) or water typically used. concentrations T 1 2 relaxation times these references change during Thus, comparison between neonates children may...
Accurate contiguous sections without breath-holding on chest CT: value of respiratory gating and ultrafast CT.M Mori, K Murata, M Takahashi, Shimoyama, T Ota, R Morita SakamotoAudio Available | Share