A5076357926- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Eicosanoids and Hypertension Pharmacology
- Hormonal Regulation and Hypertension
- Urologic and reproductive health conditions
- Cardiovascular Disease and Adiposity
- Apelin-related biomedical research
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Blood Pressure and Hypertension Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Infrastructure Maintenance and Monitoring
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- PI3K/AKT/mTOR signaling in cancer
- Long-Term Effects of COVID-19
- Analytical Chemistry and Sensors
- Alcohol Consumption and Health Effects
- Statistical Methods in Clinical Trials
- Blood disorders and treatments
- Inflammasome and immune disorders
- Cardiac Fibrosis and Remodeling
- Retinal Imaging and Analysis
- Autophagy in Disease and Therapy
- Artificial Intelligence in Healthcare and Education
American University of Beirut
2020-2024
Georgetown University
2020-2024
National Institutes of Health
2024
National Cancer Institute
2024
American University of Beirut Medical Center
2024
CSL (Switzerland)
2021
Georgetown University Medical Center
2020
Diabetic kidney disease (DKD) is a serious complication of diabetes, affecting millions people worldwide. Inflammation and oxidative stress are key contributors to the development progression DKD, making them potential targets for therapeutic interventions. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as promising class drugs, with evidence demonstrating that they can improve renal outcomes in diabetes. However, exact mechanism by which SGLT2i exert their renoprotective...
Diabetes is associated with decreased epoxyeicosatrienoic acid (EET) bioavailability and increased levels of glomerular vascular endothelial growth factor A (VEGF-A) expression. We examined whether a soluble epoxide hydrolase inhibitor protects against pathologic changes in diabetic kidney disease the inhibition VEGF-A signaling pathway attenuates diabetes-induced injury. also aimed to delineate cross talk between cytochrome P450 2C (CYP2C)–derived EETs VEGF-A. Streptozotocin-induced type 1...
Prostate-specific membrane antigen (PSMA)-targeting PET radiotracers reveal physiologic uptake in the urinary system, potentially misrepresenting activity prostatic urethra as an intraprostatic lesion. This study examined correlation between midline 18 F-DCFPyL prostate and hyperintensity on T2-weighted (T2W) MRI indication of retained urine urethra.
The identification and validation of a non-invasive prognostic marker for early detection diabetic kidney disease (DKD) can lead to substantial improvement in therapeutic decision-making. main objective this study is assess the potential role arachidonic acid (AA) metabolite 20-hydroxyeicosatetraenoic (20-HETE) predicting incidence progression DKD. Healthy patients with diabetes were recruited from Hamad General Hospital Qatar, urinary 20-HETE levels measured. Data analysis was done using...
No AccessUrology PracticeReview Articles1 Mar 2024Reply by Authorsis a reply to letterEditorial CommentEditorial Comment Charlotte Goldman Houston, William S. Azar, Sean Shenghsiu Huang, Rachel Rubin, C. Scott Dorris, and Rachael D. Sussman HoustonCharlotte Houston https://orcid.org/0000-0002-8068-5382 Department of Urology, Georgetown University, Washington, District Columbia , AzarWilliam Azar HuangSean Huang Health Management Policy, RubinRachel Rubin DorrisC. Dorris Dahlgren Medical...
270 Background: Radiotracers used in prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging have high specificity for the detection of prostate cancer (PCa), and PSMA PET/CT has seen increased use management localized PCa. However, diagnostic capability PET can be limited by intense uptake ureters, bladder, urethra due to physiologic urinary excretion. Specifically, radiotracer activity prostatic misinterpreted as a midline intraprostatic lesion if not carefully...
You have accessJournal of UrologyDiversity, Equity & Inclusion: Health Outcomes III (MP70)1 May 2024MP70-02 DOES PRE-PROSTATECTOMY MAGNETIC RESONANCE IMAGING REDUCE RACIAL DISPARITIES IN ONCOLOGIC OUTCOMES FOR AFRICAN AMERICAN PATIENTS: A PROPENSITY SCORE-MATCHED ANALYSIS Kyle C. Schuppe, Christopher Koller, Sahil Parikh, Charles Hesswani, William S. Azar, Sarah Azari, Alexander P. Kenigsberg, Nityam Rathi, Jason Hyman, David G. Gelikman, Neil Mendhiratta, Daniel Nethala, Sandeep Gurram,...
You have accessJournal of UrologyImaging/Uroradiology II (MP30)1 May 2024MP30-01 A NEW LOOK: THE PROMISING USE OF 3-DIMENSIONAL QUANTITATIVE TRANSMISSION ULTRASOUND TOMOGRAPHY FOR DETECTION PROSTATE CANCER AN EX VIVO STUDY Sahil H. Parikh, Charles Hesswani, William S. Azar, Christopher R. Koller, Kyle C. Schuppe, Alexander P. Kenigsberg, Neil Mendhiratta, Sarah Azari, Daniel Nethala, Yixuan Wu, James Wiskin, Emad Boctor, John Klock, Bradford Wood, Sandeep Gurram, Baris Turkbey, and Peter A....
You have accessJournal of UrologySurgical Technology & Simulation: Instrumentation II (MP43)1 May 2024MP43-06 IS IT TIME TO ABANDON THE TRANSRECTAL PROBE IN PROSTATE BIOPSY? William S. Azar, Christopher R. Koller, Sahil H. Parikh, Charles Hesswani, Kyle C. Schuppe, Sarah Azari, Alexander P. Kenigsberg, Neil Mendhiratta, Jason Hyman, Jibriel Noun, Jayant Siva, Daniel Nethala, David G. Gelikman, Maria J. Merino, Howard Parnes, Bradford Wood, Ismail Baris Turkbey, Sandeep Gurram, Sheng Xu, and...
You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy II (PD33)1 May 2024PD33-06 RENAL SURGERY FOLLOWING HIF2ALPHA; ANTAGONIST THERAPY: GROWTH KINETICS AND SURGICAL OUTCOMES Daniel Nethala, Jason Hyman, Nityam Rathi, Jessica Hsueh, Charles Hesswani, Christopher Koller, Alexander P. Kenigsberg, Neil Mendhiratta, Keith Lawson, Sahil Parikh, William Azar, Kyle Schuppe, Cathy Vocke, Ramaprasad Srinivasan, Sandeep Gurram, W. Marston Linehan, and Mark Ball NethalaDaniel...
You have accessJournal of UrologySurgical Technology & Simulation: Artificial Intelligence I (MP07)1 May 2024MP07-18 EVALUATION OF A BIPARAMETRIC MRI AI ALGORITHM FOR THE DETECTION PROSTATE CANCER USING SPATIAL ANNOTATIONS ON WHOLEMOUNT PATHOLOGY Charles Hesswani, Enis C. Yilmaz, Stephanie A. Harmon, David G. Gelikman, Christopher R. Koller, Sahil H. Parikh, Kyle Schuppe, William S. Azar, Daniel Nethala, Neil Mendhiratta, Alexander P. Kenigsberg, Sandeep Gurram, Baris Turkbey, and Peter...