Elísio Xerinda

ORCID: 0000-0003-0715-2034
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Research Areas
  • Global Maternal and Child Health
  • COVID-19 epidemiological studies
  • Child Nutrition and Water Access
  • Autopsy Techniques and Outcomes
  • COVID-19 Pandemic Impacts
  • Global Health and Epidemiology
  • Global Health Care Issues
  • Bacterial Infections and Vaccines
  • Vaccine Coverage and Hesitancy
  • COVID-19 and Mental Health
  • Neonatal and fetal brain pathology
  • Food Security and Health in Diverse Populations
  • Pneumonia and Respiratory Infections
  • Health disparities and outcomes
  • Maternal and Neonatal Healthcare
  • Cardiac Arrest and Resuscitation
  • Congenital Anomalies and Fetal Surgery
  • SARS-CoV-2 and COVID-19 Research
  • Poverty, Education, and Child Welfare
  • Influenza Virus Research Studies
  • Emergency and Acute Care Studies
  • Health and Conflict Studies
  • Misinformation and Its Impacts
  • Migration, Health and Trauma
  • Pregnancy and preeclampsia studies

Manhiça Health Research Centre
2022-2024

Instituto Nacional de Saúde
2024

Health Net
2023

Sana Mahtab Dianna M. Blau Zachary J. Madewell Ikechukwu U. Ogbuanu Julius Ojulong and 95 more Sandra Lako Hailemariam Legesse Joseph Bangura Quique Bassat Inácio Mandomando Elísio Xerinda Fabíola Fernandes Rosauro Varo Samba O. Sow Karen L. Kotloff Milagritos D. Tapia Adama Mamby Keita Diakaridia Sidibé Dickens Onyango Victor Akelo Dickson Gethi Jennifer R. Verani Gunturu Revathi J. Anthony G. Scott Nega Assefa Lola Madrid Hiwot Bizuayehu Tseyon Tesfaye Tirfe Shams El Arifeen Emily S. Gurley Kazi Munisul Islam Muntasir Alam Mohammad Zahid Hossain Ziyaad Dangor Vicky L. Baillie Martin Hale Portia Mutevedzi Robert F. Breiman Cynthia G. Whitney Shabir A. Madhi Yasmin Adam Janet Agaya ASM Nawshad Uddin Ahmed Dilruba Ahmed Addisu Alemu Solomon Ali Soter Ameh George Aol Solveig A. Cunningham Farida Ariuman Oluseyi Balogun Sanwarul Bari Margaret Basket Ferdousi Begum Manu Bhandari John Blevins James Bunn Courtney Bursuc Carrie Jo Cain Richard Chawana Kiranpreet Chawla Cornell Chukwuegbo Kounandji Diarra Tiéman Diarra Maureen H. Diaz Babatunde Duduyemi Karen D. Fairchild Meerjady Sabrina Flora Ashleigh Fritz Mischka Garel Brigitte Gaume Mahlet Abayneh Gizaw Nelesh P. Govender Carol L. Greene Tadesse Gure Binyam Halu Mahbubul Hoque Cleopas Hwinya Alexander M. Ibrahim Kitiezo Aggrey Igunza Ferdousi Islam Okokon Ita Amara Jambai Jennifer Johnson Jane Juma Erick Kaluma Mohammed Kamal Osman Kaykay Sartie Kenneh Sammy Khagayi Rima Koka Diakaridia Kone Jeffrey P. Koplan Nana Kourouma Dickens Kowuor Kristin LaHatte Sanjay G. Lala Kyu Han Lee Lucy Liu Hennie Lombaard

The Child Health and Mortality Prevention Surveillance (CHAMPS) Network programme undertakes post-mortem minimally invasive tissue sampling (MITS), together with collection of ante-mortem clinical information, to investigate causes childhood deaths across multiple countries. We aimed evaluate the overall contribution pneumonia in causal pathway death causative pathogens fatal children aged 1-59 months enrolled CHAMPS Network.

10.1016/s2352-4642(23)00328-0 article EN cc-by The Lancet Child & Adolescent Health 2024-01-25
Zachary J. Madewell Cynthia G. Whitney Sithembiso Velaphi Portia Mutevedzi Sana Mahtab and 95 more Shabir A. Madhi Ashleigh Fritz Alim Swarray‐Deen Tom Sesay Ikechukwu U. Ogbuanu Margaret Mannah Elísio Xerinda António Sitoe Inácio Mandomando Quique Bassat Sara Ajanovic Milagritos D. Tapia Samba O. Sow Ashka Mehta Karen L. Kotloff Adama Mamby Keita Beth A. Tippett Barr Dickens Onyango Elizabeth Oele Kitiezo Aggrey Igunza Janet Agaya Victor Akelo J. Anthony G. Scott Lola Madrid Yunus-Edris Kelil Tadesse Dufera Nega Assefa Emily S. Gurley Shams El Arifeen Ellen A. Spotts Whitney Katherine Seib Chris A. Rees Dianna M. Blau Ferdousi Begum Mohammad Mosiur Rahman Mohammed Kamal ASM Nawshad Uddin Ahmed Mahbubul Hoque Kyu Han Lee Saria Tasnim Mahbubur Rahman Tahmina Shirin Iqbal Ansary Khan Meerjady Sabrina Flora Dilruba Ahmed Khalequ Zaman Kazi Munisul Islam Mohammed Ahmed Mohammed Zahid Hossain Mustafizur Rahman Shahana Parveen Sanwarul Bari Farida Arjuman Farzana Islam Ferdousi Islam Joseph Oundo Gunturu Revathi Emily Rogena Magdalene Kuria Paul K. Mitei Florence Murila Jennifer R. Verani Doh Sanogo Nana Kourouma Seydou Sissoko Uma U. Onwuchekwu Diakaridia Sidibé Tatiana Keita Diakaridia Kone Sharon M. Tennant Carol L. Greene Jennifer Johnson Rima Koka Karen D. Fairchild Sandra Lako Erick Kaluma Samuel Pratt Baindu Kosia Ruby Fayorsey Rebecca Alkis Ramirez Rebecca Philipsborn Mischka Garel Navit T. Salzberg Jeffrey P. Koplan Robert F. Breiman Jana M. Ritter Joy Gary Sherif R. Zaki Jennifer R. Verani Jacob Witherbee Lucy Liu Shailesh Nair Jonas M. Winchell Fikremelekot Temesgen Melisachew Mulatu Yeshi

Importance Although child mortality trends have decreased worldwide, deaths among children younger than 5 years of age remain high and disproportionately circumscribed to sub-Saharan Africa Southern Asia. Tailored innovative approaches are needed increase access, coverage, quality health care services reduce mortality, but an understanding system deficiencies that may the greatest impact on is lacking. Objective To investigate which public improvements could prevented most stillbirths in...

10.1001/jamanetworkopen.2022.37689 article EN cc-by-nc-nd JAMA Network Open 2022-10-21
Lola Madrid Kartavya J. Vyas Vijaya Kancherla Haleluya Leulseged Parminder S. Suchdev and 95 more Quique Bassat Samba O. Sow Shams El Arifeen Shabir A. Madhi Dickens Onyango Ikechukwu U. Ogbuanu J. Anthony G. Scott Dianna M. Blau Inácio Mandomando Adama Mamby Keita Emily S. Gurley Sana Mahtab Victor Akelo Sulaiman Sannoh Yenenesh Tilahun Rosauro Varo Uma Onwuchekwa Afruna Rahman Yasmin Adam Richard Omore Sandra Lako Elísio Xerinda Kazi Munisul Islam Amy Wise Beth A. Tippet-Barr Erick Kaluma Sara Ajanovic Karen L. Kotloff Mohammad Zahid Hossain Portia Mutevedzi Milagritos D. Tapia Emily Rogena Francis Moses Cynthia G. Whitney Nega Assefa ASM Nawshad Uddin Ahmed Mahbubul Hoque Mohammed Kamal Mohammad Mosiur Ferdousi Begum Saria Tasnim Meerjady Sabrina Flora Farida Arjuman Iqbal Ansary Khan Tahmina Shirin Mahbubur Rahman Sanwarul Bari Shahana Parveen Farzana Islam Mohammad Zahid Hossain Kazi Munisul Islam Mohammad Sabbir Ahmed Khalequ Zaman Mustafizur Rahman Dilruba Ahmed Md Atique Iqbal Chowdhury Muntasir Alam Kyu Han Lee Ferdousi Islam Joseph Oundo Fikremelekot Temesgen Melisachew Mulatu Yeshi Alexander M. Ibrahim Tadesse Gure Yunus Edris Addisu Alemu Dadi Marami Ephrem Lemma Ayantu Mekonnen Henok Wale Tseyon Tesfaye Haleluya Leulseged Tadesse Dufera Anteneh Belachew Fentabil Getnet Surafel Fentaw Yenework Acham Stian MS Orlien Mahlet Abayneh Gizaw Emily Rogena Florence Murila Gunturu Revathi Paul K Mitei Magdalene Kuria Jennifer R. Verani Aggrey Igunza Peter Nyamthimba Elizabeth Oele Karen D. Fairchild Carol L. Greene Rima Koka Ashka Mehta Sharon M. Tennant Jennifer Johnson Tatiana Keita

Neural tube defects are common birth resulting in severe morbidity and mortality; they can largely be prevented with periconceptional maternal intake of folic acid. Understanding the occurrence neural their contribution to mortality settings where burden is highest could inform prevention health-care policy. We aimed estimate attributed seven countries sub-Saharan Africa southeast Asia.

10.1016/s2214-109x(23)00191-2 article EN cc-by The Lancet Global Health 2023-06-01
Sana Mahtab Zachary J. Madewell Shabir A. Madhi Amy Wise Peter J. Swart and 95 more Sithembiso Velaphi Inácio Mandomando Justina Bramugy Rita Mabunda Elísio Xerinda Anthony Scott Nega Assefa Lola Madrid Mulu Bweihun Fikremelekot Temesgen Dickens Onyango Victor Akelo Richard Oliech Peter Otieno Jennifer R. Verani Shams El Arifeen Emily S. Gurley Muntasir Alam Mahbubur Rahman Mohammad Zahid Hossain Samba O. Sow Karen L. Kotloff Milagritos D. Tapia Adama Mamby Keita Doh Sanogo Ikechukwu U. Ogbuanu Julius Ojulong Sandra Lako Okokon Ita Erick Kaluma Taís Meziara Wilson Portia Mutevedzi Beth A. Tippett Barr Cynthia G. Whitney Dianna M. Blau Quique Bassat Yasmin Adam Janet Agaya Sara Ajanovic Addisu Alemu Solomon Ali George Aol Henry Badji Sanwarul Bari Justina Bramugy James Bunn Richard Chawana Atique Iqbal Chowdhury Karen D. Fairchild Surafel Fentaw Meerjady Sabrina Flora Dickson Gethi Nelesh P. Govender Carol L. Greene Tadesse Gure Martin Hale Juan Carlos Hurtado Kitiezo Aggrey Igunza Farzana Islam Jennifer Johnson Tatiana Keita Sammy Khagayi Iqbal Ansary Khan Rima Koka Diakaridia Kone Nana Kourouma Magdalene Kuria Sandra Lako Sanjay G. Lala Hennie Lombaard Ronita Luke Thomas Misore Paul K Mitei Alexander M. Ibrahim Andrew Moultrie Florence Murila Nellie Myburgh Peter Nyamthimba Richard Oliech Richard Omore Uma U. Onwuchekwa Stian Magnus Staurung Orlien Louis Othieno Peter Otieno Kephas Otieno Gregory Ouma Benard Owuor Shahana Parveen Karen L. Petersen Mahbubur Rahman Natalia Rakislova Emily Rogena Doh Sanogo Tahmina Shirin Diakaridia Sidibé

Invasive Group B Streptococcus (GBS) is a common cause of early-onset neonatal sepsis and also associated with stillbirth. This study aimed to determine the proportion stillborn infants who died between 0 90 days attributable GBS using postmortem minimally invasive tissue sampling (MITS) in 7 low- middle-income countries (LMICs) participating Child Health Mortality Prevention Surveillance (CHAMPS). Deaths that occurred December 2016 2021 were investigated MITS, including culture for bacteria...

10.1093/ofid/ofad356 article EN cc-by-nc-nd Open Forum Infectious Diseases 2023-07-11

Understanding community members' knowledge of SARS-CoV-2 transmission and prevention is essential for directing public health interventions to reduce disease spread improve vaccination coverage. Here, we describe COVID-19 transmission, prevention, symptoms among residents in Mozambique. We conducted a cross-sectional survey 33,087 households Health Demographic Surveillance System Manhiça, Participants were recruited April 2021 before the Delta variant wave peak Omicron cases February 2022....

10.1371/journal.pgph.0002532 article EN public-domain PLOS Global Public Health 2023-11-01

The COVID-19 pandemic has prompted countries to swiftly implement rigorous preventive measures on a population-wide scale worldwide. However, in low-income like Mozambique this was difficult, coupled with generalised lack of knowledge how the population understood and complied these measures. This study assessed community perceptions implementation anti-COVID-19 recommended by Mozambican authorities Manhiça Quelimane districts, including confinement, social distancing, frequent handwashing,...

10.1371/journal.pone.0278439 article EN cc-by PLoS ONE 2024-05-14
Sara Ajanovic Zachary J. Madewell Shams El Arifeen Emily S. Gurley Mohammad Zahid Hossain and 95 more Kazi Munisul Islam Afruna Rahman Nega Assefa Lola Madrid Mohammednur Abdulahi Kitiezo Aggrey Igunza Florence Murila Gunturu Revathi Mugah A. Christopher Samba O. Sow Karen L. Kotloff Milagritos D. Tapia Cheik Bougadari Traor Inácio Mandomando Elísio Xerinda Rosauro Varo Milton Kincardett Ikechukwu U. Ogbuanu Phillip Nwajiobi-Princewill Alim Swarray‐Deen Ronita Luke Shabir A. Madhi Sana Mahtab Ziyaad Dangor Jeanie du Toit Victor Akelo Portia Mutevedzi Beth A. Tippett Barr Dianna M. Blau Cynthia G. Whitney Quique Bassat Fatima Solomon Gillian Sorour Hennie Lombaard Jeannette Wadula Karen L. Petersen Martin Hale Nelesh P. Govender Peter J. Swart Sanjay G. Lala Sithembiso Velaphi Richard Chawana Yasmin Adam Amy Wise Nellie Myburgh Sanwarul Bari Shahana Parveen Mohammed Kamal ASM Nawshad Uddin Ahmed Mahbubul Hoque Saria Tasnim Ferdousi Islam Farida Ariuman Mohammad Mosiur Rahman Ferdousi Begum Khalequ Zaman Mustafizur Rahman Dilruba Ahmed Meerjady Sabrina Flora Tahmina Shirin Mahbubur Rahman Joseph Oundo Alexander M. Ibrahim Fikremelekot Temesgen Tadesse Gure Addisu Alemu Melisachew Mulatu Yeshi Mahlet Abayneh Gizaw Stian MS Orlien Solomon Ali Kitiezo Aggrey Igunza Peter Otieno Peter Nyamthimba Onyango Janet Agaya Richard Oliech Joyce Were Dickson Gethi George Aol Thomas Misore Harun Owuor Christopher Muga Bernard Oluoch Christine Ochola Sharon M. Tennant Carol L. Greene Ashka Mehta Jennifer Johnson Brigitte Gaume Adama Mamby Keita Rima Koka Karen D. Fairchild Diakaridia Kone Diakaridia Sidibé Doh Sanogo Uma U. Onwuchekwa

Importance The emergence of acute neurological symptoms in children necessitates immediate intervention. Although low- and middle-income countries (LMICs) bear the highest burden diseases, there is a scarcity diagnostic therapeutic resources. Therefore, current understanding etiology emergencies LMICs relies mainly on clinical diagnoses verbal autopsies. Objective To characterize association premortem their management with postmortem-confirmed cause death among aged younger than 5 years to...

10.1001/jamanetworkopen.2024.31512 article EN cc-by-nc-nd JAMA Network Open 2024-09-03

Abstract Over 230,000 COVID-19 cases and over 2,200 deaths have been reported in Mozambique though May 2023. Understanding community members’ knowledge of SARS-CoV-2 transmission prevention is essential for directing public health interventions to reduce disease spread improve vaccination coverage. Here, we describe transmission, prevention, symptoms among residents Mozambique. We conducted a cross-sectional survey 33,087 households Health Demographic Surveillance System Manhiça,...

10.1101/2023.03.31.23288026 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-04-03

The Manhiça Health Research Centre (Manhiça HDSS) was established in 1996 Manhiça, a rural district at Maputo Province the southern part of Mozambique with approximately 49,000 inhabited households, total population 209.000 individuals, and an annual estimated birth cohort about 5000 babies. Since 2016, HDSS is implementing Child Mortality Prevention Surveillance (CHAMPS) program aiming to investigate causes death (CoD) stillbirths children under age 5 years using innovative post-mortem...

10.12688/gatesopenres.13931.1 preprint EN cc-by Gates Open Research 2023-01-20

Data collection was implemented through an initiative by the Child Health and Mortality Prevention Surveillance (CHAMPS) Network to assess whether lockdowns other social distancing policies during COVID-19 had implications for household economic status, maternal child health, healthcare accessibility pregnant women children. The data were collected from April 2021 until February 2022 a population living in rural community of Mozambique. This is located within Demographic System (HDSS) that...

10.1016/j.dib.2024.110654 article EN cc-by Data in Brief 2024-06-21

In resource-limited settings where vital registration and medical death certificates are unavailable or incomplete, verbal autopsy (VA) is often used to attribute causes of (CoD) prioritize resource allocation interventions. We aimed determine the CoD concordance between InterVA CHAMPS’s method. The (CoDs) children <5 were determined by two methods using data from seven low- middle-income countries (LMICs) enrolled in Child Health Mortality Prevention Surveillance (CHAMPS) network. first...

10.1371/journal.pgph.0003065 article EN public-domain PLOS Global Public Health 2024-07-29

<ns3:p>The Manhiça Health Research Centre (Manhiça HDSS) was established in 1996 Manhiça, a rural district at Maputo Province the southern part of Mozambique with approximately 49,000 inhabited households, total population 209.000 individuals, and an annual estimated birth cohort about 5000 babies. Since 2016, HDSS is implementing Child Mortality Prevention Surveillance (CHAMPS) program aiming to investigate causes death (CoD) stillbirths children under age 5 years using innovative...

10.12688/gatesopenres.13931.3 preprint EN cc-by Gates Open Research 2024-09-13

Introduction Malnutrition contributes to 45% of all childhood deaths globally, but these modelled estimates lack direct measurements in countries with high malnutrition and under-5 mortality rates. We investigated malnutrition’s role infant child the Child Health Mortality Prevention Surveillance (CHAMPS) network. Methods analysed CHAMPS data from seven sites (Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone South Africa) collected between 2016 2023. An expert panel assessed each...

10.1136/bmjgh-2024-017262 article EN cc-by-nc-nd BMJ Global Health 2024-12-01

Abstract Background In resource-limited settings where vital registration and medical death certificates are unavailable or incomplete, verbal autopsy (VA) is often used to attribute causes of (CoD), identify the distribution trends diseases, prioritize resource allocation interventions. However, VA findings can be non-specific, as this tool based on family members’ recall symptoms rather than objective diagnostic testing. We aimed compare CoD diagnoses obtained in stillbirths children below...

10.1101/2024.03.11.24304131 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-03-14

<ns3:p>The Manhiça Health Research Centre (Manhiça HDSS) was established in 1996 Manhiça, a rural district at Maputo Province the southern part of Mozambique with approximately 49,000 inhabited households, total population 209.000 individuals, and an annual estimated birth cohort about 5000 babies. Since 2016, HDSS is implementing Child Mortality Prevention Surveillance (CHAMPS) program aiming to investigate causes death (CoD) stillbirths children under age 5 years using innovative...

10.12688/gatesopenres.13931.2 preprint EN cc-by Gates Open Research 2024-09-05

ABSTRACT Background The COVID-19 pandemic has led countries into urgent implementation of stringent preventive measures at the population level. However, implementing these in low-income like Mozambique was incredibly difficult, coupled with lack scientific evidence on community understanding and compliance measures. This study assessed perceptions recommended by Mozambican authorities Manhiça Quelimane districts, taking confinement, social distancing, frequent handwashing, mask wearing,...

10.1101/2022.11.17.22282473 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2022-11-18

Background: Pneumonia etiology in resource-limited settings is challenging to determine due the paucity of direct lung tissue sampling. This study used post-mortem minimally invasive sampling (MITS) assess fatal pneumonia etiologies children aged 1-59 months across six sub-Saharan and one South Asian low- middle-income settings, participating Child Health Mortality Prevention Surveillance (CHAMPS) network.Methods: Deaths occurring between December 2016 2022 were investigated using MITS...

10.2139/ssrn.4546771 preprint EN 2023-01-01

Data collection was implemented through an initiative by the Child Health and Mortality Prevention Surveillance (CHAMPS) Network to assess whether lockdowns other social distancing policies during COVID-19 had implications for household economic status, maternal child health, healthcare accessibility pregnant women children. The data were collected from April 2021 until February 2022 a population living in rural community of Mozambique. This is located within Demographic System (HDSS) that...

10.2139/ssrn.4656601 preprint EN 2023-01-01

Abstract Background COVID-19 resulted in vast disruption to life the 21 st century. To quell disease spread, national governments implemented several containment measures like state of emergency, curfews, and lockdowns that likely created hardships for households. improve knowledge negative consequences these lockdowns, we examine extent which pandemic period was associated with at household level assess factors vulnerability hardships. Methods We conducted a cross-sectional survey between...

10.1101/2023.12.21.23300355 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2023-12-24
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