A5086977019- Bone fractures and treatments
- Neonatal Respiratory Health Research
- Biomedical and Engineering Education
- Bone health and osteoporosis research
- Global Maternal and Child Health
- Infant Development and Preterm Care
- Respiratory Support and Mechanisms
- Orthopaedic implants and arthroplasty
- Hip and Femur Fractures
- Engineering Education and Curriculum Development
- Intravenous Infusion Technology and Safety
- Design Education and Practice
- Cardiac, Anesthesia and Surgical Outcomes
- Biosensors and Analytical Detection
- Electrolyte and hormonal disorders
- Shoulder Injury and Treatment
- Body Contouring and Surgery
- Tribology and Wear Analysis
- Engineering Education and Pedagogy
- Renal function and acid-base balance
- Bone and Joint Diseases
- Conferences and Exhibitions Management
- Quality and Safety in Healthcare
- Elasticity and Material Modeling
- Antibiotics Pharmacokinetics and Efficacy
Rice University
2010-2025
The University of Texas at Austin
2003
Tulane University
1992-2002
Harvard University
1998-1999
The University of Texas Health Science Center at Houston
1999
Beth Israel Deaconess Medical Center
1998-1999
This study describes the design and evaluation of a portable bright-field fluorescence microscope that can be manufactured for $240 USD. The uses battery-operated LED-based flashlight as light source achieves resolution 0.8 microm at 1000x magnification in mode. We tested diagnostic capability this new instrument to identify infections caused by human pathogen, Mycobacterium tuberculosis. Sixty-four direct, decontaminated, serially diluted smears were prepared from sputa obtained 19 patients...
Deficiencies in the sterile processing of medical instruments contribute to poor outcomes for patients, such as surgical site infections, longer hospital stays, and deaths. In low resources settings, some rural semi-rural areas secondary tertiary cities developing countries, deficiencies are accentuated due lack access sterilization equipment, improperly maintained malfunctioning power operate protocols, inadequate quality control over inventory. Inspired by our fieldwork at a district...
Abstract Hip fracture among the elderly is a large and growing public health issue. Presently, all therapies approved for treatment prevention of osteoporosis involve pharmacological agents that act systemically. In this study, we evaluated feasibility preventing osteoporotic hip fractures with local, rather than systemic, therapy. Our hypothesis local therapy to increase bone density may be as effective systemic in reducing risk. Thus, goal investigation was use finite element analyses...
Objective: To describe the outcomes of infants and young children with respiratory distress when treated a novel, low-cost, stand-alone bubble Continuous Positive Airway Pressure (bCPAP) system in resource-limited setting. Methods: A non-randomized, convenience sample study pediatric unit Blantyre, Malawi, 2013. Patients weighing ≤10 kg were eligible. We compared for patients bronchiolitis, pneumonia Pneumocystis jiroveci (PJP) after treatment bCPAP. Results: Seventy percent bCPAP survived....
This article describes the design and evaluation of AutoSyP, a low-cost, low-power syringe pump intended to deliver intravenous (IV) infusions in low-resource hospitals. A constant-force spring within device provides mechanical energy depress plunger. As result, can run on rechargeable battery power for 66 hours, critical feature settings where grid may be unreliable. The is designed used with 5- 60-mL syringes fluids at flow rates ranging from 3 60 mL/hour. cost goods build one AutoSyP...
Millions of newborns die annually from preventable causes, with the highest rates occurring in Africa. Reducing neonatal mortality requires investment to scale hospital care, which includes providing hospitals appropriate technology care for small and sick newborns. Expensive medical devices designed high-resource settings often fail withstand conditions low-resource hospitals, including humidity, dust, frequent user turnover, complex maintenance, lack stable power, or difficulty sourcing...
Abstract Background The need for palliative care in sub-Saharan Africa is staggering: this region shoulders over 67% of the global burden HIV/AIDS and cancer. However, provisions these essential services remain limited poorly integrated with national health systems most nations. Moreover, evidence base remains scarce. This study chronicles development evaluation DataPall, an open-source electronic medical records system that can be used to track patients, manage data, generate reports...
The present work focuses on designing a pin-on-disc tribometer used to perform dry or lubricated wear tests according the ASTM G99 standard method. device was developed using engineering design process (EDP) based steps related problem understanding and solution construction stages. is composed of an aluminum structure, cylindrical test chamber, disk rotation control system, load cells for measuring normal tangential forces, position sensor temperature sensors. A 7” touch screen selected...
Abstract Background Medical devices are critical to providing high-quality, hospital-based newborn care, yet many of these unavailable in low- and middle-income countries (LMIC) not designed be suitable for settings. Target Product Profiles (TPPs) often utilised at an early stage the medical device development process enable user-defined performance characteristics a given setting. TPPs can also applied assess profile match existing context. Methods We developed initial 15 product categories...
Magnesium sulfate is an affordable and effective treatment for pre-eclampsia eclampsia. In settings where infusion pumps are not available to regulate the flow rate of intravenous delivery, healthcare providers must administer magnesium (MgSO4) via time-consuming painful, large-volume intramuscular injections. As alternative costly commercially syringe pumps, we developed AutoSyp, accurate, low-cost, low-powered pump designed meet needs constraints these low-resource settings. This paper...
The use of computational methods in the study bone mechanics is described, with emphasis on finite element method. In addition to stan dard for calcuiation dis placement, stress-and-strain environment refined models bone, a "remodeling ele ment" described simulate time course changes architecture that are induced by me chanical loading. algorithm, which involves re peated analyses over time, shown be feasible supercomputing platforms.
Hospitals in the developing world lack access to an affordable means of administering intravenous therapy at accuracy required for neonates. This paper presents design and performance a mechanical syringe pump delivering IV low-resource settings. Current available pumps are limited electronic disposable pumps. Commercially pumps, frequently used developed world, expensive, require highly trained technical personnel, rely on electricity source, so they unfeasible clinics. Disposable other...
Respiratory distress due to preterm birth is a significant cause of death in low-resource settings. The introduction continuous positive airway pressure (CPAP) systems treat respiratory significantly reduced mortality high-resource settings, but CPAP was only recently introduced settings cost and infrastructure limitations. We evaluated stability imposed work breathing (iWOB) five used low resource settings: the Fisher Paykel bubble CPAP, Diamedica baby Medijet nCPAP generator, first (2015)...
In many areas of the world, current methods for diagnosis infectious diseases such as malaria and tuberculosis involve microscopic evaluation a patient specimen. Advances in fluorescence microscopy can improve diagnostic sensitivity reduce time expertise necessary to interpret results. However, modern research-grade microscopes are neither available nor appropriate use settings developing world. To address this need, we designed, fabricated, tested portable, battery-powered, bright field...
Objective Evaluate a novel continuous temperature monitor in low-resource neonatal ward. Design We developed low-cost (NTM) for use settings. Accuracy of NTM was initially assessed the laboratory. Clinical evaluation then performed ward central hospital Malawi; eligible neonates (<1 week age) were recruited monitoring with and Philips Intellivue MP30 Patient Monitor. Interventions outcome measures The probes reference patient attached to infant’s abdomen, core continuously recorded up 3...
We designed and evaluated the accuracy usability of a device to regulate volume fluid dispensed during intravenous drip therapy. The mechanical system was developed in response pressing need articulated by clinicians pediatric wards throughout sub-Saharan Africa, who require tool prevent overhydration children receiving settings that lack burettes or electronic infusion pumps. is compatible with most bags limits preset amount can be adjusted 50 mL increments. Laboratory over range...
Young engineers entering an industry job are likely to be immediately placed into a division or team that is comprised of people from wide variety educational backgrounds. This will include other engineering disciplines and, depending on the industry, individuals with business, marketing, public relations, policy science work in progress describes our initial efforts implement and evaluate outcomes collaboratively teaching capstone design assigning interdisciplinary teams solve real-world...
Obese patients undergoing conscious-sedation surgery have increased perioperative morbidity because their excess abdominal tissue limits diaphragmatic excursion. We describe a simple device that might help attenuate this risk. created noninvasive suction for suspension. By lifting the burden of weight, should decrease respiratory effort. To test feasibility weight removal in relieving cardiac stress, we tested 22 supine, healthy, normal-weight subjects by measuring heart rates with and...