A5101862246- Pelvic floor disorders treatments
- Pelvic and Acetabular Injuries
- Anorectal Disease Treatments and Outcomes
- Multiple Myeloma Research and Treatments
- Hernia repair and management
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Click Chemistry and Applications
- Surgical Sutures and Adhesives
- Reconstructive Surgery and Microvascular Techniques
- Impact of Technology on Adolescents
- Job Satisfaction and Organizational Behavior
- Endometrial and Cervical Cancer Treatments
- Urinary Bladder and Prostate Research
- Plant Molecular Biology Research
- Cancer Treatment and Pharmacology
- Digital Games and Media
- Social and Intergroup Psychology
- Synthesis and biological activity
- Chronic Myeloid Leukemia Treatments
- Personality Traits and Psychology
- Bladder and Urothelial Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Venous Thromboembolism Diagnosis and Management
- Colorectal Cancer Surgical Treatments
Peking University
2013-2025
Peking University People's Hospital
2013-2025
Yunnan Agricultural University
2021-2025
Dalian Medical University
2006-2023
First Affiliated Hospital of Dalian Medical University
2006-2023
Capital University of Economics and Business
2022
Shanghai Second People's Hospital
2017
Institute of Psychology, Chinese Academy of Sciences
2014
Jilin University
2013
Institute of Crop Sciences
2013
Abstract Aim The aim of the study is to compare effect extraperitoneal high uterosacral ligament suspension (EHUS) and sacrospinous fixation on lower urinary tract symptoms (LUTS) anatomical reduction in patients with pelvic organ prolapse (POP). Methods This retrospective cohort concluded 91 POP who underwent EHUS or (SSLF) for apical repair. primary outcome was two operations reduction. main secondary outcomes included improvement questionnaire scores, satisfaction, subjective rate....
Tomato flower abscises at the anatomically distinct abscission zone that separates pedicel into basal and apical portions. During abscission, cell separation occurs only indicating distinctive molecular regulation in its cells. We conducted a transcriptome analysis of tomato tissues during ethylene promoted abscission. found was most active site with largest set differentially expressed genes when compared Gene Ontology analyses revealed enriched transcription hydrolase activities zone. also...
Abstract Background MicroRNAs (miRNAs) are identified in nearly all plants where they play important roles development and stress responses by target mRNA cleavage or translation repression. MiRNAs exert their functions sequence complementation with genes hence targets can be predicted using bioinformatics algorithms. In the past two decades, microarray technology has been employed to study involved biological processes such as biotic response, abiotic specific tissues developmental stages,...
Pelvic organ prolapse (POP) has a high incidence rate among Chinese women. Repeated mechanical stimulation is an important factor causing POP, but the injury mechanism not yet been elucidated. The purpose of this study to explore related mechanisms pelvic floor supporting tissue damage caused by force and application stem cell therapy. First, we obtained vaginal wall sacral ligament samples from clinical patients for examination. support tissues POP displayed expression inflammation immune...
Abstract Background Individuals with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs) are at risk of developing venous thromboembolism (VTE), a serious complication. There is no established clinical model for predicting VTE in the Chinese population. We develop new assessment (RAM) IMiD-associated MM patients. Methods retrospectively selected 1334 consecutive patients IMiDs from 16 medical centers China and classified them randomly into derivation validation cohorts. A...
ABSTRACT The aim of this study was to compare the tissue reactions silk fibroin scaffolds in abdominal wall, vagina, and pelvic vesico‐uterine rats. Silk were implanted subcutaneously abdominal, space, under vaginal mucosa 16 animals euthanized at 2, 4, 8, 12 weeks postoperatively. Hematoxylin eosin staining performed evaluate cellular infiltration, percentage macrophages granulocytes inside around scaffolds. amounts M1/M2 interface host evaluated through an immunofluorescence assay. degree...
The main thrust of the Integral Theory Paradigm (ITP) is that inadequate ligament collagen causes pelvic organ prolapses (POP) and symptoms, a concept validated by multiple publications which cured POP bladder/bowel/pain dysfunctions collagen-creating slings. Sling surgery for surgical cure these conditions was eliminated in United States, Europe other regulatory jurisdictions banning all mesh products (including tapes) about 2017. aim this work to inform progress highly promising...
A core concept of the Integral Theory System is that "ligaments are for structure; vagina function". The and uterus should be conserved. Because an organ, its collagen elastin, which so necessary function, cannot regenerate once they removed. Removing involves severing descending uterine artery, principal blood supply proximal part uterosacral ligaments (USLs), may cause atrophy, can future incontinence problems because loss after menopause. diagnostic algorithm guides five pelvic need...
Pelvic organ prolapse (POP) is a major health concern that affects women. Surgeons have increasingly used prosthetic meshes to correct POP. However, the most common synthetic mesh, and absorbable mesh less reported. This research aimed evaluate clinical effectiveness of porcine small intestinal submucosa (SIS).Consecutive forty POP patients who met inclusion criteria underwent pelvic reconstruction surgery with SIS between March 2012 December 2013. The patients' characteristics were recorded...
ABSTRACTThe effectiveness of empowering leadership has been the subject contrasting views. Numerous studies have adopted an interactive approach to reconciling these inconsistencies and emphasized role subordinates' competence capabilities. We join this stream discussions by pointing out that leader also plays a pivotal in subordinates. further postulate relational energy can mediate effects perceived on task performance. In Study 1, data analyses based sample 397 team members 112 leaders...
Abstract Objective To evaluate the feasibility and clinical value of combination carbon nanoparticles (CNPs) indocyanine green (ICG) for identifying sentinel lymph nodes (SLNs) in endometrial cancer. Materials Methods About 153 patients with cancer were recruited from July 2015 to May 2019. All underwent SLN biopsy according algorithm surgical staging ICG and/or CNPs. The detection rate, factors associated sensitivity, negative predictive (NPV) SLNs analyzed. Results rates combined method...
Pelvic organ prolapse (POP) is a common debilitating condition affecting approximately 30-40% of women. The FDA issued warning about polypropylene mesh used for pelvic floor repair due to erosion, exposure and other complications banned it in 2019. application stem cell therapy growth factors has strongly promoted the development tissue engineering.we intend address issues direct factors, side effects long-term exogenous treatment, directional differentiation cells. Methods: we evaluated...
Background: In-depth and clear mechanistic study is a prerequisite for new drugs to enter clinical research. Method: New chemical entity BY4008 was identified by our lab as novel highly potent EGFR JAK3 dualtarget inhibitor. A cell-based test exhibited strong antiproliferative activities against SW620 HCT116 colon cancer cells harboring KRAS mutation with IC50 of nanomolar potency. Furthermore, acridine orange/ethidium bromide (AO/EB), Hematoxylin-Eosin (H&E) DAPI staining assays flow...