A5006113916- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- MRI in cancer diagnosis
- Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Glioma Diagnosis and Treatment
- Dementia and Cognitive Impairment Research
- Radiation Detection and Scintillator Technologies
- Helicobacter pylori-related gastroenterology studies
- Cancer Cells and Metastasis
- Genetic factors in colorectal cancer
- Alzheimer's disease research and treatments
- Head and Neck Cancer Studies
- Gastroesophageal reflux and treatments
- Medical Imaging and Pathology Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Gastrointestinal Tumor Research and Treatment
Fukushima Medical University
2021-2025
Tokyo Metropolitan Institute of Gerontology
2015-2023
Kitasato University
2023
Nagoya University Hospital
2023
Kindai University
2023
Nippon Medical School
2023
Fujita Health University Hospital
2023
University of Electro-Communications
2023
International University of Health and Welfare
2016-2022
Tohoku University
2022
Abstract Differentiating recurrent brain tumor from radiation necrosis is often difficult. This study aims to investigate the efficacy of 11C-methionine (MET)-PET radiomics for distinguishing necrosis, as compared with conventional tumor-to-normal cortex (T/N) ratio evaluation. We enrolled 41 patients metastatic or glioma treated using therapy who underwent MET-PET. The area a standardized uptake value > 1.3 times that normal was contoured. Forty-two PET features were extracted and used...
The Bayesian penalized likelihood PET reconstruction (BPL) algorithm, Q.Clear (GE Healthcare), has recently been clinically applied to clinical image reconstruction. BPL includes a relative difference penalty (RDP) as function. β value that controls the behavior of RDP determines global strength noise suppression, whereas γ factor in degree edge preservation. present study aimed assess effects various factors on ability detect sub-centimeter lesions.All data were acquired for 10 min using...
Abstract Background Laparoscopic cholecystectomy (LC) is the standard treatment for symptomatic gallbladder disease. The identification of factors that reliably predict likely need to convert LC an open procedure would provide short-term benefits in terms patient education and postoperative expectations. Methods Between 1993 2004, 1179 elective LCs were attempted from a total 1339 cholecystectomies. change conversion rate between 1993–1999 2000–2004 was analysed. Factors predictive higher...
Three hundred patients who underwent absolute and relative curative gastrectomy lymph node dissection for gastric cancer were reviewed with respect to postoperative mortality; proportion of involvement according the extent dissection; number metastatic nodes dissected accuracy macroscopic evaluation microscopic tumour location. If more total increased; conversely within R0 R3 did not affect survival. Finally when presence was only macroscopically evaluated, classified incorrectly in 9.5 per...
The Omni Legend 32 PET/CT system features silicon photomultiplier (SiPM)–based detectors with bismuth germanium oxide crystals and a 32-cm axial field of view (FOV). present study aimed to determine the performance characteristics according National Electrical Manufacturers Association (NEMA) NU 2-2018 standards. <b>Methods:</b> PET component this comprises 22 detector modules; each module contains 24 blocks 72 volume 4.1 × 30 mm coupled 18 SiPM devices 6 area, resulting in an FOV cm....
Abstract Background The digital-BGO PET/CT system, Omni Legend 32, incorporates modified block sequential regularized expectation maximization (BSREM) image reconstruction and a deep learning-based time-of-flight (TOF)-like quality enhancement process called Precision DL (PDL). present study aimed to define the fundamental characteristics of PDL using phantom clinical images. Methods A NEMA IEC body was scanned 32 system. All images were acquired over 60 90 s per bed position, with 384 ×...
Abstract Background Two novel methods of image reconstruction, xSPECT Quant (xQ) and Bone (xB), that use an ordered subset conjugate gradient minimizer (OSCGM) for SPECT/CT reconstruction have been proposed. The present study compares the performance characteristics xQ, xB, conventional Flash3D (F3D) using images derived from phantoms patients. Methods A custom-designed body phantom bone SPECT was scanned a Symbia Intevo (Siemens Healthineers), reconstructed were evaluated. experiments...
Background: In clinical practice, equivocal findings are inevitable in visual interpretation of whether amyloid positron emission tomography (PET) is positive or negative. It therefore necessary to establish a more objective quantitative evaluation method for determining the indication disease-modifying drugs currently under development. Aims: We aimed determine cutoffs positivity analysis 18 F-flutemetamol PET patients with cognitive impairment and suspected Alzheimer's disease (AD). also...
The aim of this study was to examine whether a specific PPARgamma ligand can inhibit the growth human pancreatic cancer cells through induction terminal differentiation. expressed in five cell lines: Capan-1, AsPC-1, BxPC-3, PANC-1, and MIA PaCa-2. Treatment these with ligand, thiazolidinedione (TZD), resulted inhibition both cellular clonogenic growth, G1 cycle arrest. Finally, treatment p21WAF-1 increased expression differentiation markers. These results suggest that inhibits induces...
Abstract Purpose Bayesian penalised likelihood (BPL) reconstruction, which incorporates point-spread-function (PSF) correction, provides higher signal-to-noise ratios and more accurate quantitation than conventional ordered subset expectation maximization (OSEM) reconstruction. However, applying PSF correction to brain PET imaging is controversial due Gibbs artefacts that manifest as unpredicted cortical uptake enhancement. The present study aimed validate whether BPL without would be useful...
The Bayesian penalized likelihood (BPL) algorithm Q.Clear (GE Healthcare) allows fully convergent iterative reconstruction that results in better image quality and quantitative accuracy, while limiting noise. present study aimed to optimize BPL parameters for 18F-NaF PET/CT images determine the feasibility of acquisition over shorter durations clinical practice.A custom-designed thoracic spine phantom consisting several inserts, soft tissue, normal spine, metastatic bone tumor, was scanned...
The Bayesian penalized likelihood (BPL) reconstruction algorithm, Q.Clear, can achieve a higher signal-to-noise ratio on images and more accurate quantitation than ordered subset-expectation maximization (OSEM). parameter (β) in BPL requires optimization according to the radiopharmaceutical tracer. present study aimed define optimal β value required diagnose Alzheimer disease from brain positron emission tomography (PET) acquired using 18 F-fluoro-2-deoxy-D-glucose ([18 F]FDG) 11 C-labeled...
Peritoneal metastasis is a crucial factor for the prognosis in gastric cancer, but its diagnosis difficult before laparotomy. We report on utility of laparoscopy and indications detection peritoneal cancer.A total 39 patients with cancer underwent cytology investigation our department, between April 1992 2000. Laparoscopic (LP-P) was determined through macroscopic, pathological cytological diagnoses. All diagnostic imaging computed tomography (CT) ultrasound laparoscopy. Carcinoembryonic...