Masao Imai
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiovascular and Diving-Related Complications
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Integrated Circuits and Semiconductor Failure Analysis
- Advancements in Photolithography Techniques
- Heart Failure Treatment and Management
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Acute Kidney Injury Research
- Infectious Aortic and Vascular Conditions
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Vascular anomalies and interventions
- Electrolyte and hormonal disorders
- Cell Adhesion Molecules Research
Hyogo Prefectural Amagasaki General Medical Center
2018-2024
Kyoto University
2007-2019
University of Rochester Medical Center
2015
Kurashiki Central Hospital
2011-2012
University of Kochi
2012
Kobe City Medical Center General Hospital
2011
Teikyo University
2011
Kokura Memorial Hospital
2011
Recently, elevation of circulating muscle-specific microRNA (miRNA) levels has been reported in patients with acute myocardial infarction. However, it is still unclear from which part the myocardium or under what conditions miRNAs are released into blood. The purpose this study was to identify source elevated and their function cardiovascular diseases.Serum miRNA (miR)-1 miR-133a were increased significantly not only infarction but also unstable angina pectoris Takotsubo cardiomyopathy...
Background— We have noted abnormal angiographic findings—at the sites of drug-eluting stent implantation, suggesting contrast staining outside struts—that do not fulfill classic definition coronary artery aneurysm. propose a new term, peri-stent (PSS), for these findings and assess their incidence, risk factors, clinical sequelae. Methods Results— Peri-stent was defined as contour extending to ≥20% diameter. The study population consisted 3081 lesions (1998 patients) that were treated...
Aim: Severe gastrointestinal bleeding sometimes occurs in patients with aortic stenosis (AS), known as Heyde's syndrome. This syndrome is thought to be caused by acquired von Willebrand and characterized reduced large factor (vWF) multimers. However, the relationship between severity of AS loss vWF multimers unclear.Methods: We examined 31 consecutive severe AS. Quantitative evaluation for was performed using conventional ratio novel multimer index. index defined those controls.Results: Loss...
Background:A hyperdynamic state of the basal left ventricle sometimes results in obstruction ventricular outflow tract (LVOT). However, prevalence, clinical presentation, and prognostic effect LVOT takotsubo cardiomyopathy (TC) have not been fully evaluated.Methods Results:Among 933 consecutive patients who underwent emergency coronary angiography for suspected acute syndrome, 35 (3.8%) were diagnosed as TC. The cumulative 3-year incidence all-cause death, cardiac hospitalization congestive...
We have sometimes noted abnormal angiographic coronary dilatation, <50% of the reference vessel, at site sirolimus-eluting stent implantation, suggesting contrast staining outside struts and named this finding peri-stent (PSS). Little was known about optical coherence tomography findings lesions with PSS.Between May 2008 March 2010, we performed for 90 in-stent restenosis after implantation. found PSS in 20 by angiography. The differences findings, including incomplete apposition, multiple...
Optimal treatment strategies for restenosis of sirolimus-eluting stents (SES) have not been adequately addressed yet.During the 3-year follow-up 12 824 patients enrolled in j-Cypher registry, 1456 lesions 1298 underwent target-lesion revascularization (TLR). Excluding 362 undergoing TLR stent thrombosis or using modalities other than SES balloon angioplasty (BA), 1094 with SES-associated 990 treated either (537 lesions) BA (557 constituted study population analysis recurrent and after first...
Abstract Prognostic impact of anemia complicating severe aortic stenosis (AS) remains unclear. We assessed the on cardiovascular and bleeding outcomes in 3403 patients enrolled CURRENT AS registry. 835 (25%) had mild (hemoglobin 11.0–12.9 g/dl for men/11.0–11.9 women) 1282 (38%) moderate/severe (Hb ≤ 10.9 g/dl) at diagnosis AS. Mild were associated with significantly increased risks relative to no ≥13.0 men/≥12.0 primary outcome measure (aortic valve-related death or heart failure...
Aim: Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is essential after percutaneous coronary intervention (PCI). Clopidogrel a prodrug changed into active metabolite by cytochrome p450 enzymes (CYPs), especially CYP2C19. Proton pump inhibitors (PPIs) are used for the prevention of aspirin-induced gastrointestinal bleeding. PPIs also metabolized CYP2C19, although degree its contribution dependent on kind PPI. Omeprazole, PPI, has been reported to weaken effects clopidogrel....
Aims: We sought to investigate medium-term outcome of percutaneous coronary intervention (PCI) compared with artery bypass grafting (CA
Therapeutic strategies for atrial septal defect (ASD) with severe pulmonary arterial hypertension (PAH) are controversial. This study aimed to evaluate the efficacy of PAH-specific medications and subsequent transcatheter closure (ie, treat-and-repair strategy) on clinical outcomes.We enrolled 42 patients who were referred 13 institutions consideration ASD concomitant PAH underwent strategy. The endpoint was cardiovascular death or hospitalisation due heart failure exacerbated PAH.At...
Abstract Introduction Some previous studies have reported that a first‐step ethanol infusion into the vein of Marshall (EIVOM) with touch‐up radiofrequency (RF) ablation can facilitate mitral isthmus (MI) block and improves outcomes in persistent atrial fibrillation (PeAF) patients. However, effect an initial RF adjunctive EIVOM has not been fully investigated. Methods This study enrolled 233 PeAF patients undergoing pulmonary isolation linear including MI, roof line, cavotricuspid ablation....
Background Data are scarce on the role of aortic valve area (AVA) to identify those patients with asymptomatic severe stenosis (AS) who at high risk adverse events. We sought explore prognostic impact AVA in AS a large observational database. Methods and Results Among 3815 consecutive enrolled CURRENT (Contemporary Outcomes After Surgery Medical Treatment Patients With Severe Aortic Stenosis) registry, present study included 1309 conservatively managed left ventricular ejection fraction...
There are limited data regarding the risk stratification based on peak aortic jet velocity (Vmax) in patients with severe stenosis (AS).Among 3815 consecutive AS enrolled CURRENT (Contemporary Outcomes After Surgery and Medical Treatment Patients With Severe Aortic Stenosis) registry, study population consisted of 1075 conservatively managed Vmax ≥4.0 m/s left ventricular ejection fraction ≥50%. The were subdivided into 3 groups (group 1, 4.0 ≤ <4.5 m/s, N=550; group 2, 4.5 <5 N=279; 3, ≥5...
HomeCirculationVol. 126, No. 13Coronary Air Embolism and Cardiogenic Shock During Computed Tomography-Guided Needle Biopsy of the Lung Free AccessBrief ReportPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplemental MaterialFree ReportPDF/EPUBCoronary Tetsuma Kawaji, MD, Hiroki Shiomi, Yosuke Togashi, Daigo Gunji, Masao Imai, Takahiro Doi, MD...