Kenji Nakatsuma
A5073125327- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Antiplatelet Therapy and Cardiovascular Diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- Advanced MRI Techniques and Applications
- Cancer Treatment and Pharmacology
- Vascular Procedures and Complications
- Medical Imaging Techniques and Applications
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
Mitsubishi Kyoto Hospital
2017-2024
Kyoto University
2014-2024
Kyoto University of Education
2022
National Cerebral and Cardiovascular Center
2022
Saitama Medical University
2022
Shiga University of Medical Science
2022
Chikamori Hospital
2018
Kokura Memorial Hospital
2016
Kobe City Medical Center General Hospital
2016
Hyogo Medical University
2016
Objectives We sought to evaluate the prognostic impact of B-type natriuretic peptide (BNP) levels in patients with asymptomatic severe aortic stenosis (AS), who were not referred for valve replacement (AVR). Methods used data from a Japanese multicentre registry, Contemporary outcomes after sURgery and medical tREatmeNT Aortic Stenosis Registry, which enrolled 3815 consecutive AS. Of those, 387 AVR without left ventricular dysfunction very AS subdivided into four groups based on their BNP...
Whether patients with severe aortic stenosis (AS) die because of AS-related causes is an important issue for the management these patients. We used data from CURRENT AS registry, a Japanese multicenter to assess death in and identify factors associated non-cardiac mortality. enrolled 3815 consecutive median follow-up 1176 days; 1449 overall deaths comprised 802 (55.3%) cardiac 647 (44.7%) causes. Heart failure (HF) (25.7%) sudden (13.0%) caused most deaths, whereas infection malignancy...
Abstract Limitations of the ablation index background Ablation (AI) is a novel marker lesion quality from radiofrequency (RF) catheter ablation. However, AI reliability has not been fully validated by experimental data. The aim present study to validate for estimating size using different settings RF parameters: contact angle, power delivery, and force (CF). Methods results We evaluated in porcine hearts (N = 108) after application at three angles myocardium: perpendicular (90°), oblique...
Background: There is a paucity of data on the effect optimal intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared with standard PCI or artery bypass grafting (CABG) in patients multivessel disease.
Background:In the setting of elective percutaneous coronary intervention (PCI), intravascular ultrasound (IVUS)-guided PCI is associated with a reduction in incidence target vessel revascularization (TVR), but impact IVUS on long-term clinical outcome emergency for ST-segment elevation acute myocardial infarction (STEMI) still unclear.Methods and Results:The subjects consisted 3,028 STEMI patients who underwent primary within 24 h symptom onset CREDO-Kyoto registry. Of these, 932 (31%)...
To evaluate the influence of a history cancer on clinical outcomes in coronary artery disease (CAD) patients who underwent percutaneous intervention (PCI).In Coronary REvascularization Demonstrating Outcome Study Kyoto (CREDO-Kyoto) PCI/coronary bypass grafting (CABG) Registry Cohort-2, there were 12 180 CAD received PCI with stents. There 1109 (cancer group) and 11 071 without (non-cancer group). The cumulative 5-year incidences cardiac death heart failure (HF) hospitalization significantly...
Age and sex are important considerations in the choice between percutaneous coronary intervention (PCI) artery bypass grafting (CABG) daily clinical practice.Of 25 816 patients enrolled multicenter Coronary Revascularization Demonstrating Outcome Study Kyoto (CREDO-Kyoto; Cohort-1, n=9877; Cohort-2, n=15 939), present study population consisted of 5651 (men, n=3998; women, n=1653) with triple-vessel disease who were considered to be pertinent comparisons PCI CABG (PCI, n=3165; CABG, n=2486)....
Background:Inter-facility transfer for primary percutaneous coronary intervention (PCI) from referring facilities to PCI centers causes a significant delay in treatment of ST-segment elevation acute myocardial infarction (STEMI) patients undergoing PCI. However, little is known about the clinical outcomes STEMI inter-facility Japan.
Background The detailed causes of death in non–ST-segment–elevation myocardial infarction (NSTEMI) have not been adequately evaluated compared to those ST-segment elevation (STEMI). Methods study population was 6,228 AMI patients who underwent percutaneous coronary intervention (STEMI: 4,625 and NSTEMI: 1,603 patients). primary outcome all-cause death. Results Within 6 months after AMI, the adjusted mortality risk significantly different between NSTEMI STEMI (HR: 0.83, 95%CI: 0.67–1.03, P =...
The functional impact of downstream coronary stenoses on left main artery (LMCA) stenosis has not been fully elucidated. This study therefore aimed to use in vitro and vivo experiments assess two novel equations that predict the true fractional flow reserve (FFR) a with concomitant stenoses.Two were derived. One equation predicts an LMCA (Equation A), other FFR both anterior descending circumflex arteries B). validated models circulation. agreements between apparent (FFRapp), predicted...
Background: There is a scarcity of studies comparing the clinical outcomes after percutaneous coronary intervention (PCI) for women and men stratified by presentation acute syndromes (ACS) or stable artery disease (CAD).
Background Adjunctive thrombus aspiration ( TA ) during primary percutaneous coronary intervention PCI was reported to promote better and myocardial reperfusion. However, long‐term mortality benefit of remains controversial. The objective this study is investigate the clinical impact on outcomes in patients with ST ‐segment elevation infarction (STEMI) undergoing . Methods Results CREDO ‐Kyoto AMI Registry a large‐scale cohort acute revascularization 2005–2007 at 26 hospitals Japan. Among...
To investigate the effect of malignancy on outcomes patients with severe aortic stenosis (AS) and management strategy for AS malignancy. Using data 3815 in a retrospective multicentre registry [CURRENT (Contemporary after sURgery medical tREatmeNT Aortic Stenosis) registry], we compared 3-year clinical among three groups based status: currently under treatment including best supportive care (malignancy group), history without any current (past or (no group). Patients group (n = 124) were...
Abstract There were no data comparing the in-hospital outcomes after transcatheter aortic valve implantation (TAVI) with those surgical replacement (SAVR) in Japan. Among consecutive patients severe AS between April 2018 and December 2020 CURRENT Registry-2, we identified 1714 who underwent (TAVI group: 1134 patients, SAVR 580 patients). Patients TAVI group much older (84.4 versus 73.6 years, P < 0.001) more often had comorbidities than group. In-hospital death rate was numerically lower...
Background:In ST-segment elevation myocardial infarction (STEMI), QRS score at presentation ECG may reflect the progression of and facilitate prediction degree salvage achieved by reperfusion therapy. Methods Results:Admission electrocardiogram (ECG) was studied in 2,607 patients with STEMI undergoing primary percutaneous coronary intervention (PCI) within 24 h symptom onset.Patients were classified into 3 groups according to score: low (0-3, n=1,227), intermediate (4-7, n=810), high (≥8,...
The comparative efficacy of second-generation (G2) vs. first-generation (G1) drug-eluting stents (DES) for calcified coronary lesions is unknown.Methods and Results:We compared the 3-year clinical outcomes patients with G1- or G2-DES according to presence absence as assessed in an angiographic core laboratory using data from 2 large-scale prospective multicenter randomized trials, RESET NEXT. G1-DES were implanted 299 1,033 patients, respectively, Calc stratum (≥1 lesion moderate/severe...
There are limited data regarding the risk stratification based on peak aortic jet velocity (Vmax) in patients with severe stenosis (AS).Among 3815 consecutive AS enrolled CURRENT (Contemporary Outcomes After Surgery and Medical Treatment Patients With Severe Aortic Stenosis) registry, study population consisted of 1075 conservatively managed Vmax ≥4.0 m/s left ventricular ejection fraction ≥50%. The were subdivided into 3 groups (group 1, 4.0 ≤ <4.5 m/s, N=550; group 2, 4.5 <5 N=279; 3, ≥5...
Abstract Background Electroanatomic voltage mapping (EAVM) of the left atrium (LA) with multielectrodes is usually acquired during sinus rhythm (SR), and feasibility EAVM atrial fibrillation (AF) unclear. Methods We performed LA both SR AF in 44 patients undergoing catheter ablation for validated optimal cutoff value low‐voltage area (LVA) detecting LVA defined as bipolar voltages ≤0.5 mV SR. Results In each session, mean 829 552 points were by rhythm, respectively. Mean proportion was 4.9%...