A5100732519- Cardiovascular Health and Disease Prevention
- Viral Infections and Immunology Research
- Peripheral Artery Disease Management
- Thyroid Disorders and Treatments
- Blood Pressure and Hypertension Studies
- Respiratory viral infections research
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Pancreatic function and diabetes
- Magnolia and Illicium research
- Cardiac Arrhythmias and Treatments
- Pharmacological Effects of Natural Compounds
- Cerebrovascular and Carotid Artery Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Neurological disorders and treatments
- Mesenchymal stem cell research
- Thyroid Cancer Diagnosis and Treatment
- Ginger and Zingiberaceae research
- Plant chemical constituents analysis
- Transcranial Magnetic Stimulation Studies
- Acute Myocardial Infarction Research
- Telomeres, Telomerase, and Senescence
- Lipoproteins and Cardiovascular Health
- Mechanisms of cancer metastasis
Beijing Obstetrics and Gynecology Hospital
2024
Peking University Shougang Hospital
2012-2024
Third Affiliated Hospital of Harbin Medical University
2024
Capital Medical University
2021-2024
Harbin Medical University
2024
Hangzhou Normal University
2024
University of Macau
2024
Affiliated Hospital of Hangzhou Normal University
2024
Tianjin Medical University General Hospital
2024
Northwestern Polytechnical University
2024
Abstract Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the counteraction which represents a promising approach to safeguard visual function. Recently, mesenchymal stem cell transplantation (MSCT) has demonstrated immense potential treat ocular disorders, in extracellular vesicles (EVs), particularly exosomes, have emerged effective ophthalmological therapeutics. However, whether and how MSCT protects photoreceptors against apoptotic injuries remains...
This study aims to identify the periodontitis factor that activates excessive autophagy in pancreatic β cells, resulting organic lesions of islet tissues and diminished insulin secretion, thereby accelerating progression diabetes mellitus (DM).
Introduction: The prevalence of thyroid nodules has been increasing, and there are few research data on the risk factors in Chinese population. In this study, we aimed to determine by retrospectively investigating physical examination records a cohort “healthy” individuals Beijing, China. Methods: This was retrospective cross-sectional study. database Medical Examination Centre (MEC) searched. Physical data, blood test ultrasound etc., from 2015 2017 were accessed. Only those that recorded...
The present study aimed to determine the characteristics of patients with dermatomyositis (DM) in order identify predictors cancer these patients. Data 239 DM, treated at Yuhuangding Hospital between 1997 and 2016, was retrospectively assessed. patients' demographic, clinical, survival laboratory data were analyzed. Of patients, 43 developed malignancies. In 30 (69.77%) malignancy detected within 1 year before or after DM diagnosis. There 15 (34.88%) fatalities. Lung most common type...
Background . Despite the many studies examining thyroid cancers, effect of autoantibodies on differentiated carcinoma (DTC) remains unclear. Objective To investigate association between serologic (ATAs) and DTC, we retrospectively evaluated data nodules obtained from patients who underwent surgery. Methods Data 1,638 surgery were evaluated. Thyroid autoimmunity was assessed by presence thyroglobulin (TgAb) or peroxidase antibodies (TPOAb). Results Among our study cohort, prevalence elevated...
Enterovirus 71 (EV71) is one of the common causative agents hand, foot and mouth disease (HFMD), associated with several outbreaks neurological complications including encephalitis. This study investigated polymorphisms interferon gamma (IFN-γ)+874 T/A interleukin 10 (IL-10)−1082 G/A in 65 Chinese patients EV71 encephalitis 113 HFMD without complications. The IFN-γ+874 IL-10−1082 were determined by polymerase chain reaction (PCR)–amplification refractory mutation system (ARMS)...
Magnolol and its isomer honokiol are polyphenols with anti-oxidative anti-inflammatory activities. We evaluated the effects of magnolol supplementation alone or in combination hen diets during late laying cycle. A total 540 Jingfen pink-shell hens (50 weeks old) were randomly assigned to six treatments: a control diet supplemented 300 mg/kg (M300), (H300), phenols magnolol/honokiol ratio 2:1 (M200H100), 1:2 (M100H200), 1:1 (M150H150). Compared that control, all groups had higher rates M300,...
Changes in the intestinal microbiota indirectly impact health of mucosa distal to intestine, particularly respiratory tract. However, effects dysbiosis on regulation syncytial virus (RSV) infection are not clear. In this study, we examined altering pulmonary immune response against RSV infection. BALB/c mice were treated with streptomycin before study altered response. The ingestion led a marked alteration reduced abundance Lactobacillus and Clostridium genera, followed by greatly aggravated...
Salmonella pullorum is one of the most harmful pathogens to avian species. Magnolol and honokiol, natural compounds extracted from Magnolia officinalis, exerts anti-inflammatory, anti-oxidant antibacterial activities. This study was conducted evaluate effects dietary supplemental magnolol honokiol in broilers infected with S. pullorum. A total 360 one-day-old were selected randomly divided into four groups six replicates: negative control group (CTL), pullorum-infected (SP), supplemented 300...
Qian-Hu is a well-known traditional Chinese medicine used for the treatment of respiratory diseases and pulmonary hypertension. We compared relaxant effects pyranocoumarin compounds, including (+)-praeruptorin A (Pra-C), Pd-Ia (=(+/-)-praeruptorin A), pteryxin, peucedanocoumarin II (P-II) 8-methoxy-psoralen (8-MOP) purified from Bai-Hua (BQ) in isolated rabbit tracheas arteries. Pra-C, pteryxin produced significant tracheal preparations constricted with 40 mM KCl or 10 microM acetylcholine....
Aim As a substrate of cytochrome P450 (CYP) 3A5, tacrolimus is characterised by narrow therapeutic index and large inter-individual variability. Our objective was to determine the influence CYP3A5 genetic polymorphisms on pharmacokinetics acute rejection in Chinese renal transplant recipients. Methods Thirty-five recipients treated with our centre were genotyped for single nucleotide polymorphisms, CYP3A5*1 (6986A) CYP3A5*3 (6986G). These patients divided into following three groups:...
Hepatic steatosis is a big hurdle to treat type 2 diabetes (T2D). Fasting-mimicking diet (FMD) has been shown be an effective intervention in dyslipidemia of T2D. However, fasting may impair the normal glucose metabolism. Human umbilical cord-derived mesenchymal stem cell (UC-MSC) transplantation discovered regulate immune reactions and reduce hyperglycemia diabetes. effect UC-MSCs on improving lipid metabolism disorder not quite satisfactory. We have investigated efficacy comparison...
Abstract Magnolol is a multifunctional polyphenol rich in Magnolia officinalis . The objective of this study was to investigate the effects magnolol on growth performance, carcass traits, antioxidant capacity, and gut health broiler chickens. A total 240 1‐day‐old broilers were randomly allocated into five dietary treatments: control (Ctrl); diet supplemented with 100, 200, or 300 mg/kg (M100, M200, M300); 200 bacitracin zinc (PC). results showed that linearly decreased feed conversion ratio...
The aim of this retrospective single-center study was to analyze the immediate results, failures and complications percutaneous mechanical thrombectomy using Rotarex catheter in treatment peripheral artery occlusion.In study, we identified a total 42 patients who underwent at our institution. Procedural outcomes were evaluated.The cohort consisted (31 men 11 women), aged 32-93 years (median 68 years). number external iliac occlusion 5, with common femoral superficial 28, profound 2,...
The lambda-like ST-elevation electrocardiography (ECG) pattern is extremely rare in patients with type 2 myocardial infarction (T2MI) triggered by coronary spasm. When this ECG appears, sudden cardiac death (SCD) caused lethal ventricular arrhythmia may occur because clinicians do not pay sufficient attention to phenomenon.We describe a 41-year-old man who presented steep down-sloping ST-segment elevation, paroxysmal tachycardia, severe sinus bradycardia, and intermittent complete...
Objectives . The present study was done to investigate the relationship between carotid-femoral pulse wave velocity (CFPWV) and biomarkers such as homocysteine (Hcy), N-terminal pro-brain natriuretic peptide (NT-proBNP), urine albumin (microalbumin) (UAE) in vascular-related diseases. Methods 656 subjects were enrolled into our study. There 377 patients with hypertension, 231 coronary heart disease, 154 diabetes mellitus, 186 healthy subjects. They divided four groups according number of...