Ayelet Ollech

ORCID: 0000-0003-0967-3968
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About
Contact & Profiles
Research Areas
  • Dermatology and Skin Diseases
  • Cutaneous lymphoproliferative disorders research
  • Autoimmune and Inflammatory Disorders Research
  • Allergic Rhinitis and Sensitization
  • Immunodeficiency and Autoimmune Disorders
  • Research on Leishmaniasis Studies
  • Vascular Malformations and Hemangiomas
  • Food Allergy and Anaphylaxis Research
  • Chemotherapy-related skin toxicity
  • Colorectal Cancer Treatments and Studies
  • Psoriasis: Treatment and Pathogenesis
  • Vascular Malformations Diagnosis and Treatment
  • Mast cells and histamine
  • Fungal Infections and Studies
  • Drug-Induced Adverse Reactions
  • Vascular Tumors and Angiosarcomas
  • Genetic and rare skin diseases.
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Chronic Lymphocytic Leukemia Research
  • Trypanosoma species research and implications
  • Ear and Head Tumors
  • Poxvirus research and outbreaks
  • Inflammatory Bowel Disease
  • Acne and Rosacea Treatments and Effects
  • Bartonella species infections research

Shaare Zedek Medical Center
2024-2025

Hebrew University of Jerusalem
2024-2025

Sheba Medical Center
2021-2024

Tel Aviv University
2005-2024

Rabin Medical Center
2005-2020

Northwestern University
2018-2020

Lurie Children's Hospital
2020

Post-transplant diabetes mellitus (PTDM) is a common and potentially serious complication after solid organ transplantation. There are only few data, however, about the incidence of DM in patients undergoing lung transplantation.The medical records 119 consecutive who underwent transplantation from 1998 to September 2004 were reviewed. Patients divided three groups according their status, including pre-transplant DM, PTDM group those without DM. Patient all laboratory data reviewed clinical...

10.1016/j.ejcts.2008.01.050 article EN European Journal of Cardio-Thoracic Surgery 2008-03-13

Cutaneous manifestations of dedicator cytokinesis 8 gene (DOCK8) deficiency, a combined type T and B cell immunodeficiency, previously designated as autosomal recessive hyper IgE syndrome, includes dermatitis skin infections. There are limited treatment options for related to the syndrome.To describe cohort patients with DOCK8 deficiency focus on their cutaneous manifestations.A retrospective study all children genetic diagnosis treated at Sheba Medical Center between 1/1/2003 1/1/2021 was...

10.1111/1346-8138.15955 article EN The Journal of Dermatology 2021-05-27

This study investigates serum cell-free DNA fluctuations in patients with herpes zoster or post-herpetic neuralgia, offering insight into the tissue damage and inflammatory dynamics associated these conditions. A single-centre combined cross-sectional longitudinal was conducted 59 to assess levels neuralgia. Cell-free extracted from blood samples of neuralgia compared healthy controls. The findings demonstrated elevated zoster, which remained for 3 months longer following treat-ment. These...

10.2340/actadv.v105.42137 article EN cc-by-nc Acta Dermato Venereologica 2025-01-03

10.1016/j.jaip.2025.02.030 article EN The Journal of Allergy and Clinical Immunology In Practice 2025-03-01

Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting up to 20% of children. Methotrexate (MTX) used off-label as systemic treatment for AD patients unresponsive topical therapies, but limited data exist regarding its safety and efficacy in children, especially those < 4 years old. To further investigate MTX younger patients, we screened the medical records three referral centers between 2016 2022 identified 28 infants toddlers old with treated MTX. Mean age upon...

10.3390/jcm12165409 article EN Journal of Clinical Medicine 2023-08-20

Israel is endemic for Old-World cutaneous leishmaniasis. The most common species Leishmania major. However, the available treatment options are limited. This study’s objective was to compare authors’ experience with different antimony intralesional treatments of major A retrospective evaluation undertaken cases leishmaniasis treated by pentavalent in a university-affiliated medical centre Israel. previous sodium stibogluconate (Pentostam®) compared current meglumine antimoniate...

10.2340/actadv.v104.35089 article EN cc-by-nc Acta Dermato Venereologica 2024-04-29

Propranolol is the mainstay of treatment for infantile haemangioma. Despite its good safety profile, it not risk-free. Guidelines propranolol initiation and monitoring have been suggested, but protocols vary among practitioners.This study sought to assess prevalence adverse events clinically significant fluctuations in haemodynamic parameters children with haemangioma during a day-hospitalization setting.Children treated department tertiary paediatric medical centre 2008-2014 were identified...

10.1111/jdv.14955 article EN Journal of the European Academy of Dermatology and Venereology 2018-03-24

There is a paucity of data on the use biologic therapy in recalcitrant pediatric psoriasis. The current study presents psoriasis cases treated with agents tertiary referral center.In this retrospective case series, were collected all patients ≤18 years old severe biological from 2010 through 2016 children's hospital. We included demographic data, previous systemic treatments, reason for discontinuation or switch to other efficacy and side effects.There 10 patients, mean age 5.75 (±3.3) our...

10.1080/09546634.2018.1476655 article EN Journal of Dermatological Treatment 2018-05-14

Abstract Background In the literature, there are minimal data for treatment of grade 2 or 3 morbilliform/atypical target lesion rashes secondary to sorafenib vemurafenib given patients with advanced stage cancer. This poses a dilemma clinicians, particularly in neoplastic disease whom other optional treatments limited. Methods The cohort included on all attending dermato‐oncological clinic at tertiary medical center that presented 2011–2014 widespread rash following vemurafenib. All were...

10.1111/ijd.13153 article EN International Journal of Dermatology 2016-01-29

Patients with primary immunodeficiency disorders (PIDs) often suffer from recurrent infections because of their inappropriate immune response to both common and less pathogens. These patients may present unique severe cutaneous infectious manifestations that are not in healthy individuals be more challenging diagnose treat.To describe a cohort PIDs atypical presentations skin infections, who posed diagnostic and/or therapeutic challenge.This is retrospective study pediatric PID were treated...

10.3389/fped.2023.1103726 article EN cc-by Frontiers in Pediatrics 2023-03-06

Psoriasis and psoriatic arthritis can present simultaneously or separately in children may pose a diagnostic challenge. To compare the dermatological manifestations pediatric patients with without arthritis. A retrospective case-control study of ≤ 18 years old at Sheba Medical Center was conducted between 2011 2021. Patients versus psoriasis-only were compared according to body surface area (BSA) involvement, cutaneous distribution, severity skin disease, response treatment related side...

10.3390/jcm13010242 article EN Journal of Clinical Medicine 2023-12-31

Abstract Background Data regarding the course and treatment of pigmented purpuric dermatoses (PPD) in paediatric population are limited. Although treatments for purpura not well established, vitamin C rutoside have been reported to be an effective option widely utilized. Objective To assess clinical utility patients with PPD treated at Ann & Robert H. Lurie Children’s Hospital Chicago between 2008 2018. Methods A retrospective review all children managed our hospital 2018 was performed....

10.1111/jdv.16397 article EN Journal of the European Academy of Dermatology and Venereology 2020-04-01

The incidence of epidermal growth factor receptor inhibitor (EGFRI)-induced papulopustular rash is 60-85%.To investigate prophylactic topical treatment for EGFRI-induced rash.A single-center, randomized, double-blind, placebo-controlled trial. Adult cancer patients initiating with EGFRIs were randomized to receive facial chloramphenicol 3% + prednisolone 0.5% (CHL-PRED) ointment, (CHL) or aqua cream (AQUA). primary end points the ≥grade 3 using Common Terminology Criteria Adverse Events...

10.1159/000511869 article EN Dermatology 2020-12-30

Skin eruptions are prevalent among patients with inflammatory bowel diseases (IBD), often associated therapies and frequently leading to dermatological consults treatment interruptions. We aimed assess the impact of joint shared decision-making in a multidisciplinary (MDT) IBD-DERMA clinic.This retrospective cohort study assessed consecutive group IBD who were referred for consultation an MDT clinic at tertiary referral center Israel.Over 1 year, 118 evaluated MDT-IBD-DERMA clinic: 68...

10.1177/17562848211053112 article EN cc-by-nc Therapeutic Advances in Gastroenterology 2021-01-01

Leishmaniasis, mainly cutaneous leishmaniasis (CL), is endemic in Israel. In recent years, the diagnosis of has transitioned to a molecular diagnosis.

10.3390/microorganisms12101950 article EN cc-by Microorganisms 2024-09-26

Abstract Background/Objectives Joint manifestations are a feature of many pediatric skin disorders, among them psoriasis, autoimmune and autoinflammatory diseases, hypermobility as an adverse effect certain medications. Identifying joint disease early is important for intervention prevention chronic damage. However, musculoskeletal complaints common determining whether symptoms warrant rheumatology referral arthritis can be challenging. Methods Pediatric dermatologists were surveyed their...

10.1111/pde.14454 article EN Pediatric Dermatology 2020-12-04

Systemic immunosuppressants are used off-label to treat paediatric patients with moderate-to severe atopic dermatitis (AD) for whom topical treatment has failed. A large real-life cohort of AD treated systemic immunosuppressive treatments is described in order guide dermatologists’ prescribing practices when faced a moderate to-severe patient who failed or contraindication treatment, phototherapy, biological agents Janus kinase inhibitors.

10.1093/bjd/ljad222 article EN British Journal of Dermatology 2023-07-05
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