A5035145387- Adenosine and Purinergic Signaling
- Cellular Mechanics and Interactions
- Peptidase Inhibition and Analysis
- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Cancer, Hypoxia, and Metabolism
- Dental Health and Care Utilization
- Oral and gingival health research
- Cloud Computing and Resource Management
- Reproductive System and Pregnancy
- MicroRNA in disease regulation
- Graphene and Nanomaterials Applications
- Dental Trauma and Treatments
- Pharmacological Effects of Natural Compounds
- Organ and Tissue Transplantation Research
- Neurological Complications and Syndromes
- Natural Antidiabetic Agents Studies
- Dental Radiography and Imaging
- Cardiovascular Issues in Pregnancy
- Enterobacteriaceae and Cronobacter Research
- Distributed and Parallel Computing Systems
- Dental Education, Practice, Research
- Advanced Chemical Sensor Technologies
- Bone health and treatments
- Ethnobotanical and Medicinal Plants Studies
Glostrup Hospital
2022-2025
Copenhagen University Hospital
2020-2025
Rigshospitalet
2016-2025
Sambalpur University
2024
Rajasthan Dental College and Hospital
2024
D.Y. Patil University
2023-2024
Pacific Dental College and Hospital
2024
Manubhai Patel Dental College and Hospital
2024
Sankalchand Patel University
2024
Gautam Buddha University
2023-2024
Osteoporosis is a condition of excessive and uncoupled bone turnover, in which osteoclastic resorption exceeds osteoblastic formation, resulting an overall net loss, fragility, morbidity. Although numerous treatments have been developed to inhibit loss by blocking resorption, understanding the mechanisms behind incomplete. The purinergic signaling system emerging be pivotal regulator homeostasis, extracellular ADP has previously shown powerful osteolytic agent vitro. We report here that...
A recent genome-wide association study (GWAS) identified with variants in X-linked CLDN2 and MORC4, PRSS1-PRSS2 loci chronic pancreatitis (CP) North American patients of European ancestry. We selected 9 from the reported GWAS replicated CP Indian by genotyping 1807 unrelated Indians Indo-European ethnicity, including 519 1288 controls. The etiology was idiopathic 83.62% alcoholic 16.38% patients. Our confirmed a significant 2 gene (rs4409525—OR 1.71, P = 1.38 x 10-09; rs12008279—OR 1.56,...
Abstract Post-menopausal osteoporosis is a condition that affects millions worldwide and places huge socio-economic burden on society. Previous research has shown an association of loss function SNPs in the gene for purinergic receptor P2X7R with low bone mineral density, increased rates vertebral fractures post-menopausal women. In this study we use mouse model oestrogen deficiency-induced BALB/cJ −/− to show absence resulted loss. Osteoclast precursors were isolated from both +/+ mice then...
REVIEW article Front. Endocrinol., 19 September 2012Sec. Bone Research Volume 3 - 2012 | https://doi.org/10.3389/fendo.2012.00116
Introduction: The use of locally administered medication (LAM) agents such as minocycline, metronidazole, and tetracycline antimicrobials has drawbacks, including the development microorganism resistance, exorbitant pricing, limited accessibility. Thus, there is a need for safer more affordable alternatives. Numerous natural therapies have been found to be superior in this situation. In study, efficacy tulsi extract LAM agent was assessed it compared with curcumin, which currently used...
Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in interorgan cross talk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin β4 (TMSB4X) as most upregulated secreted protein media of contracting C2C12 myotubes. TMSB4X was also acutely increased plasma exercising humans irrespective insulin resistance condition or exercise mode. Treatment mice with did not ameliorate metabolic...
There is increasing interest to develop antimicrobial aids from alternative sources such as medicinal plants for the treatment of infectious diseases. Neem and clove are known have properties.The study aimed at detecting antibacterial antifungal activity neem extract against Streptococcus mutans Candida albicans.Strains S. C. albicans selective media growing micro-organisms were procured. Antimicrobial was assessed using two methods, by determining minimum inhibitory concentration (MIC)...
This paper introduces a new dataset RWU3D that consists of ToF depth images and the corresponding amplitude as well high-resolution Stereo respective ground truth data. The disparity are also available. is recorded for real world scenarios can be used to obtain more accurate estimation particular scene through fusion characteristics. We built system comprising state art sensor, RGB cameras, laser scanner obtaining truth. data from different sensors calibrated one coordinate system, which...
Abstract PRESTO was established in 2022 and is a concerted effort by leading European experts the field of P2XRs extracellular ATP to promote advance transition clinic P2XR-targeting therapies. Following inaugural meeting Ferrara which set foundations action generated interest from many groups institutes, second covered preclinical clinical aspects as common route different diseases, recognising multidisciplinary collaborative approach required for number medical conditions.
Multiple myeloma is a malignant expansion of plasma cells and aggressively affects bone health. We show that P2X7 receptor altered growth, which primary in vitro. Expression on six human cell lines confirmed the heterogeneity associated with receptor. Pharmacology 2′(3′)-O-(4-benzoylbenzoyl) adenosine 5′-triphosphate (BzATP) as agonist showed dose-dependent membranal pores RPMI-8226 (p = 0.0027) blockade antagonists. Ca2+ influx increasing doses BzATP 0.0040) was also inhibited Chronic...
Background Gingivitis is a common oral health condition characterized by inflammation of the gingiva, which, if left untreated, can progress to more severe forms periodontal disease. Effective hygiene practices play crucial role in managing gingivitis, but comparative efficacy different aids remains unclear. This study aimed evaluate and compare various maintaining patients with considering gender degree gingivitis as potential influencing factors. Methods A total 120 participants were...
In this work, we present a robot-dialogue framework to handle sophisticated robot-initiated interaction. We introduce robotic assistant equipped with dialogue system in household assistance context. To become truly collaborative companion, the is able engage proactive conversation for task assistance. The actions are triggered by recognition of persons or specific objects. evaluate our system, conducted user study 17 participants laboratory environment where users were interact via natural...