A5100741600- Heart Failure Treatment and Management
- Cancer-related molecular mechanisms research
- Nutrition, Genetics, and Disease
- Molecular Biology Techniques and Applications
- Genomics and Phylogenetic Studies
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Atrial Fibrillation Management and Outcomes
- Plant Stress Responses and Tolerance
- Cardiac Arrest and Resuscitation
- Potassium and Related Disorders
- Circular RNAs in diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Hormonal Regulation and Hypertension
- MicroRNA in disease regulation
- Microbial Natural Products and Biosynthesis
- Electrolyte and hormonal disorders
- Enzyme Production and Characterization
- Biological Stains and Phytochemicals
- Plant nutrient uptake and metabolism
- Urinary and Genital Oncology Studies
- Allelopathy and phytotoxic interactions
- Carbon and Quantum Dots Applications
- Virology and Viral Diseases
- Nausea and vomiting management
Qingdao Agricultural University
2025
Guizhou Normal University
2024
Shandong University
2024
The First Hospital of Kunming
2023-2024
Chinese Academy of Agricultural Sciences
2024
Institute of Plant Protection
2024
Hebei Science and Technology Department
2024
Hebei Academy of Sciences
2024
Shandong First Medical University
2024
Shandong Provincial Hospital
2024
In patients with heart failure (HF), increased arginine vasopressin concentrations are associated more severe disease, making an attractive target for therapy. However, AVP is difficult to measure due its in vitro instability and rapid clearance. Copeptin, the C-terminal segment of preprovasopressin, a stable reliable surrogate biomarker serum concentrations.The Biomarkers Acute Heart Failure (BACH) trial was 15-center, diagnostic prognostic study 1641 acute dyspnea; 557 HF were included...
Abstract This study aimed to clarify the effects of drought during flowering period on carbon and nitrogen metabolism, growth, yield Tartary buckwheat. buckwheat cultivar Jinqiao 2 was treated with well-watered (CK), slight soil-drought stress (LD), moderate (MD), severe (SD), soil water potential maintained at − 0.02 0.03, 0.04 0.05, 0.05 0.06, 0.06 0.07 MPa, respectively. With prolonged growth an increase in stress, antioxidant enzyme activities contents substances enzymes related...
Depression is a disease with significant global social burden. Single nucleotide polymorphisms (SNPs) are correlated the development of depression. This study investigates relationship between in GPHN and ATP6V1D gene promoter regions susceptibility to depression Chinese population. To provide new insights into identifying SNPs for predicting We conducted case-control involving 555 individuals 509 healthy controls. rs8020095 rs3759755, rs10144417, rs2031564, rs8016024 region were genotyped...
Lipid peroxidation and redox imbalance are hallmarks of ferroptosis, an iron-dependent form cell death. Growing evidence suggests that dysregulation in glycolipid metabolism iron homeostasis substantially contribute to the development hepatocellular carcinoma (HCC). However, there is still a lack comprehensive understanding regarding specific transcription factors capable coordinating initiate onset ferroptosis. We discovered overexpression SOX8 leads impaired mitochondria integrate,...
Synechococcus elongatus PCC 7942 ( S. 7942) is a model cyanobacteria species for circadian clock mechanism studies. It has also been widely used as bioreactor to produce biofuels and other metabolic products. Quantitative real-time PCR (qPCR) technology the most commonly method studying expression of specific genes, in which relative level target genes calibrated by stably expressed internal reference genes. In this work, we examined nine candidate time-course samples under no treatment...
Real-time quantitative PCR (RT-qPCR) has a high sensitivity and strong specificity, is widely used in the analysis of gene expression. Selecting appropriate internal reference genes key to accurately analyzing expression changes target by RT-qPCR. To find out most suitable for studying Broussonetia papyrifera under abiotic stresses (including drought, salt, ZnSO4 treatments), seven different tissues B. papyrifera, as well roots, stems, leaves were test materials, 15 candidate screened based...
Reference genes are commonly used as a reliable approach to normalize the results of quantitative polymerase chain reaction (qPCR), and reduce errors in relative quantification gene expression. Suitable reference belonging numerous functional classes have been identified for various types species tissue. However, little is currently known regarding most suitable bone, specifically sheep mandibular condyle. Sheep important study human bone diseases, particularly temporomandibular diseases....
Abstract Background Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder defined by xerostomia and keratoconjunctivitis sicca, its etiology remains unknown. N6-methyladenosine (m 6 A) the predominant posttranscriptional modification in eukaryotic mRNAs dynamically regulated m A regulators. Dysregulation of closely associated with several disorders, but role pSS This study investigated potential A-related regulators patients dry eye. Methods cross-sectional included forty-eight...
Abstract Background Depression is a common chronic debilitating disease with heavy social burden. single nucleotide polymorphisms (SNPs) can affect the function of microRNAs (miRNAs), which in turn associated neurological diseases. However, association between SNPs located promoter region miR-17-92 and risk depression remains unclear. Therefore, we investigated rs982873, rs9588884 rs1813389 incidence Chinese population. Methods used GWAS (Genome-wide study) NCBI (National Center for...
Crosstalk regulation is widespread in Streptomyces species. Elucidating the influence of a specific regulator on target biosynthetic gene clusters (BGCs) and cell metabolism crucial for strain improvement through regulatory protein engineering. PteF PteR are two regulators that control biosynthesis filipin, which competes building blocks with avermectins avermitilis. However, little known about effects avermectin biosynthesis. In this study, we investigated their impact global metabolism....
The heterogeneity of hepatocellular carcinoma (HCC) is linked to tumor malignancy and poor prognosis. Nevertheless, the precise mechanisms underlying development cholangiocellular phenotype (CCA) within HCC remain unclear. Emerging studies support that cross-talk among host cells microenvironment (TME) sustains cancer cell plasticity. This study sought identify specific types involved in formation CCA elucidate their functional roles progression HCC. Single-cell RNA sequencing was employed...
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Abstract Background Esophageal cancer is a highly aggressive malignancy with limited treatment options and poor prognosis. The identification of novel molecular subtypes therapeutic targets crucial for improving clinical outcomes. Method In this study, we investigated the role R‐spondin 2 (RSPO2) in esophageal its association mitochondrial metabolism. Using bioinformatics analysis publicly available datasets, identified panel RSPO2‐related metabolism genes their expression patterns cancer....
Purpose: To evaluate the performance of Framingham cardiovascular risk score (FRS)/pooled cohort equations (PCE)/China prediction for atherosclerotic disease (ASCVD) (China-PAR model) in a prospective Chinese older adults. Patients and Methods:We assessed 717 adults aged 75-85 years without ASCVD at baseline from Sichuan province China.The participants were followed annually 2011 to 2021.We obtained participants' information through medical records physical examination evaluated their...
Although regional anesthesia is common, the procedure results in feelings of uncertainty and anxiety some patients. Increased care needed for these patients under general anesthesia. Few studies have focused on intraoperative caring experience during This study procedures involving anesthesia.The descriptive phenomenology method Husserl was employed. Semi-structured interviews were conducted with a purposive sample five Grade III-A hospitals Zhengzhou City, Henan Province. The seven-step...