A5100608939- Healthcare and Venom Research
- Cytokine Signaling Pathways and Interactions
- Cancer Mechanisms and Therapy
- Cancer, Hypoxia, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Stress, Anesthesia, and Immune Response
- Acupuncture Treatment Research Studies
- Natural product bioactivities and synthesis
- Immunotherapy and Immune Responses
- interferon and immune responses
- Cancer Immunotherapy and Biomarkers
- Bee Products Chemical Analysis
- Phytochemical Studies and Bioactivities
- Medical Image Segmentation Techniques
- Traditional Chinese Medicine Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Retinal Imaging and Analysis
- Optical Coherence Tomography Applications
- Liver physiology and pathology
- Mesenchymal stem cell research
- SARS-CoV-2 and COVID-19 Research
- Genetically Modified Organisms Research
- RNA Interference and Gene Delivery
- Cancer-related molecular mechanisms research
- Respiratory viral infections research
Second Military Medical University
2014-2024
Peking University First Hospital
2024
Kunming Institute of Zoology
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
1997-2024
Peking University
2024
Changhai Hospital
2012-2023
Jiangxi Agricultural University
2022
Institute of High Energy Physics
2022
Chinese Academy of Sciences
2022
University of Hong Kong
2022
Traditional Chinese medicine (TCM) is an important part of the treatment primary liver cancer (PLC) in China; however, current instructions for integrative use traditional and Western PLC are mostly based on expert opinion. There no evidence-based guideline clinical practice this field. Therefore, Shanghai Association Integrative Medicine has established a multidisciplinary working group to develop guideline, which focuses most questions about TCM during treatment. This was developed...
// Hongju Yang 1,* , Qian Li 2,* Jie Niu 3,* Bai 2 Dejun Jiang 1 Zhihua Wan Qingmei Fei Ping Wei and Song The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China Human Genetics Center Yunnan 3 Institute Medicinal Biology Chinese Academy Science, * These authors have contributed equally to this work Correspondence to: Bai, email: Keywords : NAA10, miR-342-5p, miR-608, colon cancer Received June 03, 2015 Accepted October 14, Published December 04, Abstract miRNAs...
Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated favourable effects against acute insults. Nevertheless, underlying mechanisms governing this hepatoprotection remain obscure. In present study, we hypothesized that macrophages their M1/M2 activation critically involve conferred by fibrosis. Our findings demonstrated manifested a beneficial role for host survival apoptosis resistance....
Transcatheter arterial chemoembolization (TACE) is the most widely used primary treatment for unresectable hepatocellular carcinoma (HCC) because of its survival benefit, although clinical effect still far from satisfactory. In China, there has been a long history using traditional Chinese medicine in liver cancer and other malignancies. this study, authors evaluated combined therapy with TACE JDF granule preparation (a herbal formula) patients HCC on survival. Clinical data, including...
This study was designed to evaluate the analgesic effect of wrist-ankle acupuncture (WAA) for patients with primary liver cancer (PLC) after transcatheter arterial chemoembolization (TACE). Sixty PLC post-TACE visual analog pain intensity scores greater than 3 were divided equally into two groups receiving either WAA or oral morphine sulphate (MOR) pain. Pain reassessed at 1, 2, 4, and 6 h intervention. Patients also monitored adverse reactions treatment. recorded when first felt TACE showed...
Background Congenital myopathies are a clinical, histopathological and genetic heterogeneous group of inherited muscle disorders that defined on peculiar architectural abnormalities in the fibres. Although there have been at least 33 different causes disease, significant percentage congenital remain genetically unresolved. The present study aimed to report novel TUBA4A variant two unrelated Chinese patients with sporadic myopathy. Methods A comprehensive strategy combining laser capture...
Background: Currently, most therapies of postembolization syndrome following transcatheter arterial chemoembolization (TACE) aim directly at a single symptom, thus leading to limitations. Objectives: To seek for systematic approach prevent and treat the syndrome, we carried out this study observe effect ginsenosides (GS) dexamethasone (Dex) in alleviating TACE. Methods: In randomized, double-blinded controlled trial, 120 patients with primary liver cancer were divided into 4 groups, 30 each...
Melittin (MEL) has been reported to exhibit anti-cancer effects in vitro against several types of cancer. Long non-coding RNA (lncRNA) ADAMTS9-AS2 can be used as a tumor suppressor. However, there is insufficient data on the potential link between MEL and hepatocellular carcinoma (HCC).RT-qPCR, CCK-8, colony formation, scratch wound healing transwell assays were detect function or HCC cells. Furthermore, Western blot analysis was applied determine that whether an association existed with...
Since the first SARS-CoV-2 outbreak in late 2019, genome has harbored multiple mutations, especially spike protein mutations. The currently fast-spreading Omicron variant that manifests without symptoms or with upper respiratory diseases been recognized as a serious global public health problem. However, its pathological mechanism is largely unknown. In this work, rhesus macaques, hamsters, and BALB/C mice were employed animal models to explore pathogenesis of (B.1.1.529). Notably,...
Melittin is a 26-residue, amphipathic, cell-penetrating, α-helical anti-hepatoma peptide isolated from bee venom.
Liver hepatocellular carcinoma (LIHC) and cholangiocarcinoma (CHOL) are common primary liver cancers worldwide. stem cells have biopotential to differentiate into either hepatocytes cholangiocytes, the phenotypic overlap between LIHC CHOL has been acceptable as a continuous cancer spectrum. However, few studies directly investigated underlying molecular mechanisms CHOL.To identify candidate genes CHOL, three data series including GSE31370, GSE15765 GSE40367 were downloaded from Gene...
Practical statistical analysis of diffusion tensor images is considered, and we focus primarily on methods that use metrics based Euclidean distances between powers tensors. First, describe a family anisotropy measures scale invariant power-Euclidean metric, which are useful for visualisation. Some properties the derived practical considerations discussed, with some examples. Second, discuss weighted Procrustes imaging interpolation smoothing, compare different set examples as well...
Optical coherence tomography (OCT) is a three-dimensional non-invasive imaging technique that can generate images of the eye at microscopic level to help diagnosis diseases. However, OCT often suffer from inhomogeneity and are corrupted by speckle noise, posing challenges automated image segmentation analysis. In this paper, novel method proposed segment retinal layers in images. The uses coarse-to-fine approach includes: (1) A variational retinex model enhance details as well correct...
This work is aimed at investigating the effect of melittin on identified key genes in bladder cancer (BC) and further providing a theoretical basis for BC treatment. GSE35014 downloaded from Gene Expression Omnibus (GEO) database was used to screen differentially expressed (DEGs) cells control. Results showed that total 389 upregulated 169 downregulated were identified. Subsequently, GO analysis, KEGG pathway enrichment PPI network analysis employed disclose crucial signaling pathways...
Abstract Aim Thermal ablation therapy has recently emerged as a promising noninvasive treatment modality for localized solid malignancies. Except its direct tumor‐cell‐killing effect on local tumor tissues, the immunomodulatory also long been noticed which too substantial clinical outcome, but it is complicated. Though much investigated and rich evidences have achieved, fundamental state profile of immunomodulation by thermal in cancer patients, exact mechanism, especially systematic...