Styliani Mantziari
A5013958297- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Bariatric Surgery and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Lung Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Diet and metabolism studies
- Congenital Diaphragmatic Hernia Studies
- Nutrition and Health in Aging
- Hernia repair and management
- Body Contouring and Surgery
- Gastroesophageal reflux and treatments
- Multiple and Secondary Primary Cancers
- Enhanced Recovery After Surgery
- Radiomics and Machine Learning in Medical Imaging
- Appendicitis Diagnosis and Management
- Medical Imaging Techniques and Applications
- Abdominal Surgery and Complications
- Venous Thromboembolism Diagnosis and Management
- Intestinal and Peritoneal Adhesions
- Pharmacology and Obesity Treatment
- Ultrasound in Clinical Applications
University of Lausanne
2016-2025
University Hospital of Lausanne
2015-2025
University Medical Center Utrecht
2024
Hôpital Claude Huriez
2017-2023
Karolinska University Hospital
2023
Karolinska Institutet
2023
Hôpital Orthopédique de la Suisse Romande
2011-2020
University Hospital of Zurich
2017
University of Insubria
2017
Background. Surgical stress during major surgery may be related to adverse clinical outcomes and early quantification of response would useful allow prompt interventions. The aim this study was evaluate the acute phase protein albumin in context postoperative response. Methods. This prospective pilot included 70 patients undergoing frequent abdominal procedures different magnitude. Albumin (Alb) C-reactive (CRP) levels were measured once daily starting day before until (POD) 5. Maximal Alb...
To test postoperative serum albumin drop (ΔAlb) as a marker of surgical stress response and early predictor clinical outcomes.Prospective cohort study (NCT02356484). Albumin was prospectively measured in 138 patients undergoing major abdominal surgery. Blood samples were collected before surgery on days 0, 1 2 3. ΔAlb compared to the modified estimation physiologic ability (mE-PASS) score correlated performances C reactive protein (CRP), procalcitonin (PCT) lactate (LCT). Postoperative...
Roux-en-Y gastric bypass may present long-term complications that require revisional surgery or even reversal to normal anatomy. Data on the indications, surgical technique, and outcomes of RYGB remain scarce. We identified 48 cases reversals with complete 90-day follow-up within a multi-centric international retrospective database elective secondary bariatric surgery. The operations were performed between 2010 2024 in high-volume referral centers Europe USA. collected body weight,...
In Brief Objectives: To assess the impact of neoadjuvant chemoradiotherapy (NCRT) on anastomotic leakage (AL) and other postoperative outcomes after esophageal cancer (EC) resection. Background: Conflicting data have emerged from randomized studies regarding NCRT AL. Methods: Among 2944 consecutive patients operated for EC between 2000 2010 in 30 European centers, treated by surgery (n = 593) were compared with those primary 1487). Multivariable analyses propensity score matching used to...
Although 18F- FDG PET/CT is validated in baseline workup of esophageal cancer to detect distant metastases, it remains underused assessing local staging and biology the primary tumor. This study aimed evaluate association between PET/CT-derived parameters cancer, its clinico-pathological features prognosis.All patients (n = 86) with adenocarcinoma or squamous cell operated 2005 2014 were analyzed. Linear regression was used identify clinico-pathologic associated tumor's maximal Standardized...
To define "best possible" outcomes for secondary bariatric surgery (BS).Management of poor response and long-term complications after BS is complex under-investigated. Indications types reoperations vary widely postoperative complication rates are higher compared to primary BS.Out 44,884 performed in 18 high-volume centers from 4 continents between 06/2013-05/2019, 5,349 (12%) cases were identified. Twenty-one outcome benchmarks established low-risk patients, defined as the 75th percentile...
Adipose tissue plasticity is orchestrated by molecularly and functionally diverse cells within the stromal vascular fraction (SVF). Although several mouse human adipose SVF cellular subpopulations have now been identified, we still lack an understanding of functional variability stem progenitor cell (ASPC) populations across fat depots. To address this, performed single-cell bulk RNA sequencing (RNA-seq) analyses >30 SVF/Lin- samples four depots, revealing two ubiquitous ASPC (hASPC) with...
Abstract Introduction Internal hernia (IH) after Roux-Y gastric bypass (RYGB) can lead to extended small bowel ischemia if it not recognized and treated promptly. The aim of this study is show whether improvement in mesenteric defect (MD) closure reduces the incidence IH. Patients Methods Retrospective analysis prospectively collected data from our database including all patients who underwent laparoscopic RYGB between 1999 2015. usual technique was a retrocolic/retrogastric RYGB. We divided...
Abstract Background Obesity is associated with varying degrees of metabolic dysfunction. In this study, we aimed to discover markers the severity impairment in men obesity via a multiomics approach. Methods Thirty-two morbidly who were candidates for Roux-en-Y gastric bypass (RYGB) surgery prospectively followed. Nine healthy adults served as controls. Deep phenotyping, including targeted metabolomics, transcriptomics, and brain magnetic resonance imaging (MRI), was performed. Results...
Objective: To assess the outcomes of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in patients with prior fundoplication. Summary Background Data: Obesity gastroesophageal reflux disease (GERD) often coexist, posing clinical challenges. Fundoplication is standard treatment for GERD refractory to medical therapy. Managing obesity after fundoplication complex while RYGB preferred addressing both GERD, its use post-fundoplication requires further evaluation. Methods: Retrospective...
Abstract Background Conflicting results have been reported regarding the predictive value of preoperative psychological assessment and weight outcome after bariatric surgery. This might be attributed to different factors affecting early loss long-term loss. Herein, we investigated whether psychiatric profile was associated with BMI both (1 year) (5 years) Roux-en-Y gastric bypass (RYGB). Methods Prospective observational cohort study patients undergoing RYGB between 2013 2019. Symptoms...
Background: Postbariatric hypoglycemia (PBH) is a challenging condition affecting quality of life patients after bariatric surgery.However, its incidence and predictive factors remain debated.Objectives: To determine the PBH, identify predictors PBH assess association with weight trajectory surgery.Setting: University Hospital.Methods: Prospective observational cohort study including 222 nondiabetic who underwent Roux-en-Y gastric bypass between 2014 2021, had an oral glucose tolerance test...
This study assessed the accuracy of preoperative staging in patients undergoing oncological esophagectomy for adenocarcinoma and squamous cell carcinoma. All surgery resectable esophageal cancer a university hospital from 2005 to 2016 were identified our institutional database. Patients with neoadjuvant treatment excluded avoid bias down-staging effects. Routinely, all had an upper endoscopy biopsy, thoracoabdominal CT scan, 18-FEG PET-CT, endoscopic ultrasound. Preoperative was compared...
This study aimed to compare clinicopathologic, oncologic, and health-related quality of life (HRQL) outcomes following neoadjuvant chemoradiation (nCRT) chemotherapy (nCT) in the ENSURE international multicenter study.nCT nCRT are standards care for locally advanced esophageal cancer (LAEC) treated with curative intent. However, no published randomized controlled trial date has demonstrated superiority either approach.ENSURE is an consecutive patients undergoing surgery LAEC (2009-2015)...