A5100423953- Chromosomal and Genetic Variations
- RNA modifications and cancer
- Diabetes and associated disorders
- Photosynthetic Processes and Mechanisms
- RNA Research and Splicing
- Pancreatic function and diabetes
- Diet, Metabolism, and Disease
- Plant Molecular Biology Research
- Mycorrhizal Fungi and Plant Interactions
- Plant Gene Expression Analysis
- Genomics and Phylogenetic Studies
- Wheat and Barley Genetics and Pathology
- GABA and Rice Research
- Plant Stress Responses and Tolerance
- Genetics and Plant Breeding
- Gut microbiota and health
- Lipid metabolism and biosynthesis
- Genetically Modified Organisms Research
- Retinal Diseases and Treatments
- Cocoa and Sweet Potato Agronomy
- Plant Disease Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Retinal Development and Disorders
- Bamboo properties and applications
- Plant nutrient uptake and metabolism
Fudan University
2022-2025
Chinese Academy of Sciences
2015-2024
University of Chinese Academy of Sciences
2015-2024
Chongqing University
2023-2024
State Forestry and Grassland Administration
2024
International Bamboo and Rattan Organization
2024
China Academy of Chinese Medical Sciences
2024
Institute of Chinese Materia Medica
2024
China Medical University
2024
Chongqing Emergency Medical Center
2024
Abstract For most sequenced flowering plants, multiple whole-genome duplications (WGDs) are found. Duplicated genes following WGD often have different fates that can quickly disappear again, be retained for long(er) periods, or subsequently undergo small-scale duplications. However, how expression, epigenetic regulation, and functional constraints associated with these gene a still requires further investigation due to successive WGDs in angiosperms complicating the trajectories. In this...
The piRNA pathway plays an important role in maintaining genome stability the germ line by silencing transposable elements (TEs) from fly to mammals. As a highly conserved component, Piwi is widely expressed both cells and somatic Drosophila ovary required for production cell types. In addition its known cap maintain germline stem (GSCs), this study has demonstrated that novel functions of promote differentiation. knockdown escort causes reduction (EC) number accumulation undifferentiated...
Long-range communication between intestinal symbiotic bacteria and extra-intestinal organs can occur through circulating bacterial signal molecules, neural circuits, or cytokines hormones from host cells. Here we report that Nod1 ligands derived act as molecules directly modulate insulin trafficking in pancreatic beta The cytosolic peptidoglycan receptor its downstream adapter Rip2 are required for cells a cell-autonomous manner. Mechanistically, upon recognizing cognate ligands, localize to...
Transposons are mobile and ubiquitous DNA molecules that can cause vast genomic alterations. In plants, it is well documented transposon mobilization strongly repressed by methylation; however, its regulation at the posttranscriptional level remains relatively uninvestigated. Here, we suggest RNA marked m 6 A methylation be localized in stress granules (SGs). Intriguingly, SG-localized AtALKBH9B selectively demethylates a heat-activated retroelement, Onsen , thereby releases from spatial...
Plants can sense temperature changes and adjust their growth accordingly. In Arabidopsis, high ambient temperatures stimulate stem elongation by activating a key thermoresponsive regulator, PHYTOCHROME INTERACTING FACTOR 4 (PIF4). Here, we show that warmth promotes the nighttime transcription of GI, which is necessary for temperature-induced TOC1. Genetic analyses suggest GI prevents excessive inhibiting PIF4, with this regulatory mechanism being partially reliant on repressed ELF3 HY5,...
Abstract Background Rosemary extract (RE) has been reported to exert antioxidant property. However, the application of RE in late-phase laying hens on egg quality, intestinal barrier and microbiota, oviductal function not systematically studied. This study was investigated detect potential effects performance, serum parameters, heath, cecal microbiota metabolism, gene expressions hens. A total 210 65-week-old “Jing Tint 6” were randomly allocated into five treatments with six replicates...
Moso bamboo (Phyllostachys edulis) known as Mao Zhu (MZ) in Chinese exhibits various forms with distinct morphological characteristics. However, the evolutionary relationship among MZ and mechanisms of culm shape variation are still lacking. Here, main differences were identified variation, which confirmed by analysing (799 culms) (458 populations. To unravel genetic basis underlying variations, 20 subjected to whole-genome resequencing. Further analysis yielded 3 230 107 high-quality SNPs...
<title>Abstract</title> The health benefits of herbal plants are fundamentally determined by their bioactive compounds, which exhibit substantial variations across species and processing techniques. fresh tea leaves (<italic>Camellia sinensis</italic>) transform into six distinct types through specific methods, making them a potential model herb for investigating relationship between chemical classes diseases. Here, we employed ultra-performance liquid chromatography-mass spectrometry...
Abstract Aberrant differentiation, driven by activation of normally silent tissue-specific genes, results in a switch cell identity and often leads to cancer progression. The underlying genetic epigenetic events are largely unexplored. Here, we report ectopic the hepatobiliary-, intestinal- neural-specific gene one cut homeobox 2 ( ONECUT2) various subtypes lung cancer. ONECUT2 expression was associated with poor prognosis RAS-driven adenocarcinoma. overexpression promoted malignant growth...
Drought drastically affects plant growth, development and productivity. Plants respond to drought stress by enhancing sugar accumulation water transport. Homeodomain-leucine zipper (HD-Zip) transcription factors (TFs) participate in various aspects of growth response. However, the internal regulatory mechanism HD-Zips moso bamboo (Phyllostachys edulis) remains largely unknown. In this study, we identified an HD-Zip member, PeHDZ72, which was highly expressed shoots roots induced drought....
Abstract Background Light provides the energy for photosynthesis and determines plant morphogenesis development. Low light compromises photosynthetic efficiency leads to crop yield loss. It remains unknown how rice responds low stress at a proteomic level. Results In this study, quantitative analysis with isobaric tags relative absolute quantitation (iTRAQ) was used 1221 differentially expressed proteins (DEPs) were identified from wild type plants grown in control or condition (17%...
Delimiting species boundaries among closely related lineages often requires a range of independent data sets and analytical approaches. Similar to other organismal groups, robust circumscriptions in fungi are increasingly investigated within an empirical framework. Here we attempt delimit clade lichen-forming endemic Asia, the Hypogymnia hypotrypa group (Parmeliaceae). In current classification, includes two species: H. flavida, which separated based on distinctive reproductive modes, former...
Herbal medicine has been widely used in the treatment of various diseases; however, adverse reactions cannot be ignored. Most previous studies have ignored relationship between factors geographical areas/batches and toxicity. This study Polygonum multiflorum (PM) as an example to analyze toxicity speculated on hepatotoxicity-inducing components PM based high content screening, UHPLC-Q-TOF/MS Progenesis QI software analysis. The results show that was obviously different among areas, most...
Inositol hexaphosphate (IP6) is a phytochemical widely found in grains and legumes that plays an anti-cancer role. However, the mechanism underlying inhibition of colorectal cancer metastasis by IP6 through host genes, gut microbiota, their interactions remain elusive. In this study, 16S rRNA sequencing was used to study effect on microbiota orthotopic transplantation model mice. The transcriptome changes genes relationship with microbiota. results showed composition mice significantly...
Abstract Nitrogen (N) deposition is a pervasive anthropogenic change that can alter the dynamics and storage of carbon (C) in tropical soils by altering transformation plant litter C to soil organic (SOC). The response fungi may be particularly important for explaining how N affects SOC forests because they are primary decomposers litter. Fungi grouped into different ecological guilds, or functional groups, which often have contrasting responses same environmental change. However, little...