A5026635983- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Rheumatoid Arthritis Research and Therapies
- Dengue and Mosquito Control Research
- Virology and Viral Diseases
- Spondyloarthritis Studies and Treatments
- Zoonotic diseases and public health
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Influenza Virus Research Studies
- Bone and Joint Diseases
- Thin-Film Transistor Technologies
- Respiratory viral infections research
- Inflammatory mediators and NSAID effects
- Viral Infections and Immunology Research
- Silicon and Solar Cell Technologies
- Vector-Borne Animal Diseases
- Plant Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Systemic Lupus Erythematosus Research
- Osteoarthritis Treatment and Mechanisms
- Organic Electronics and Photovoltaics
- Insect symbiosis and bacterial influences
- Malaria Research and Control
- Plant Toxicity and Pharmacological Properties
Chinese PLA General Hospital
2019-2024
Air Force Medical University
2024
Guangdong Provincial Center for Disease Control and Prevention
2012-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2021
First Affiliated Hospital of Chinese PLA General Hospital
2017
Guangzhou Center for Disease Control and Prevention
2003-2016
China-Japan Friendship Hospital
2008-2014
Institute of Microbiology
2012
Dongguan People’s Hospital
2012
Peking Union Medical College Hospital
2006
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet the 2003/2004 outbreak in city Guangzhou, China, were nearly identical. Phylogenetic analysis suggested an independent viral invasion animal to this new episode. Combining all existing data but excluding singletons, we identified 202 single-nucleotide variations. Among them, 17 are polymorphic civets only. ratio nonsynonymous/synonymous nucleotide substitution collected 1 yr apart different...
A disease outbreak with dengue-like symptoms was reported in Guangdong Province, China, October 2010. Testing results confirmed that the pathogen causing chikungunya virus. Phylogenic analysis indicated this virus a member of Indian Ocean clade East/Center/South African subgroup
Objectives Frequent outbreaks of dengue are considered to be associated with an increased risk for endemicity the disease. The occurrence a large number indigenous cases in consecutive years indicates possibility changing epidemic pattern Guangdong, China. Methods To have clear understanding current epidemic, retrospective study epidemiological profile, serological response, and virological features infections from 2005–2011 was conducted. Case data were collected National Notifiable...
Mosquito viruses cause unpredictable outbreaks of disease. Recently, several unassigned isolated from mosquitoes, including the Omono River virus (OmRV), were identified as totivirus-like viruses, with features similar to those Totiviridae family. Most reported members this family infect fungi or protozoans and lack an extracellular life cycle stage. Here, we a new strain OmRV determined high-resolution structures for using single-particle cryo-electron microscopy. The feature unexpected...
Abstract Background Acute hemorrhagic conjunctivitis is a common disease in China. As notifiable disease, cases are registered by ophthalmologists on the AHC surveillance system. An outbreak caused CA24v was observed Guangdong Province 2007 National Disease Supervision Information Management System. Three years later, larger occurred during August-October period (2010). To characterize and compare genetic diversity of CA24v, which determined to be cause outbreak, epidemiology molecular...
In 2015, an unexpected multiple outbreak of dengue occurred in Guangdong, China. total, 1,699 cases were reported, which 1,627 verified to have DENV infections by nucleic acid or NS1 protein, including 44 DENV-1, 1126 DENV-2, 18 DENV-3 and 6 DENV-4, the other confirmed ELISA. Phylogenetic analyses DENV-1 isolates identified two genotypes (I V). The predominant DENV-2 Cosmopolitan genotypes, likely originated from Malaysia. assigned into genotype I III. All DENV-4 imported originally...
We report on a study conducted in Guangdong Province, China, to characterize behaviors and perceptions associated with transmission of pathogens pandemic potential highly exposed human populations at the animal-human interface. A risk factor/exposure survey was administered individuals high levels exposure wildlife. Serological testing performed evaluate prior infection several wildlife viral pathogens. Follow up serology subset cohort as well close contacts individuals. 1,312 were enrolled...
ObjectiveThe aim of this study was to investigate the infectiousness re-positive coronavirus disease 2019 (COVID-19) patients.MethodsAll nucleic acid testing (NAT) performed using throat swabs, nasopharyngeal and anal which were tested by Fluorescent quantitative realtime PCR. Re-positive cases defined as a discharged patient who re-tested positive NAT. Micro-neutralization severe acute respiratory syndrome 2 (SARS-CoV-2) based on methods for (SARS) Middle East (MERS) viruses. IgM IgG...
Objective: Sacroiliitis, a prerequisite to the diagnosis of ankylosing spondylitis, can be ascertained by CT when MRI is not available. Oblique coronal an increasingly popular approach examining sacroiliitis. The goal this study was understand how oblique compared with axial scanning in terms raters’ concordance diagnosing Methods: 52 subjects < 45 years age at onset their chronic lower back pain were sequentially scanned X-ray, and CT. acquired images graded two experienced,...
A novel orbivirus had been identified as a member of the Orbivirus genus, which was isolated from pooled Culex fatigans mosquitoes in Guangdong China, named Fengkai virus (FKOV). The cytopathic effects (CPEs) on both Aedes albopictus cells (C6/36) and mammalian cell lines (Vero BHK-21) emerged cultures inoculated above in. Experimental confirmation genus conducted by Real-time PCR based Ion Torrent Next-Generation sequencing. Identities VP1, VP2 VP3 amino acid sequences between Tibet (TIBOV)...
Objective To establish a method for the isolation of Zika virus and to gather experiences viral isolation. Methods Suckling mice at age 1-3 days were inoculated with serum samples positive through intracranial injection. All sacrificed 6 after Viral nucleic acids extracted from brain, heart, liver, spleen, lung, kidney, muscle, skin intestine tissue analyzed by real-time RT-PCR. The supernatants brain tissues used subculturing. Nested PCR was performed amplify NS5 gene isolated virus....