A5100386886- Plant Gene Expression Analysis
- Phytochemicals and Antioxidant Activities
- Plant biochemistry and biosynthesis
- Metabolomics and Mass Spectrometry Studies
- Phytoplasmas and Hemiptera pathogens
- Postharvest Quality and Shelf Life Management
- Horticultural and Viticultural Research
- Allelopathy and phytotoxic interactions
- Enzyme-mediated dye degradation
- Plant tissue culture and regeneration
- Identification and Quantification in Food
- Plant Reproductive Biology
- Microbial Metabolism and Applications
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Plant Virus Research Studies
- Weed Control and Herbicide Applications
- Forest Insect Ecology and Management
- Insect symbiosis and bacterial influences
- Plant Pathogenic Bacteria Studies
- Natural product bioactivities and synthesis
- Biochemical and biochemical processes
- Cocoa and Sweet Potato Agronomy
- Plant Pathogens and Fungal Diseases
- Heat shock proteins research
South China Agricultural University
2013-2024
Hebei University of Chinese Medicine
2024
Hanzhong People's Hospital
2024
Huazhong Agricultural University
2007-2024
Soochow University
2022
Ningbo University
2017-2022
Chinese Academy of Medical Sciences Dermatology Hospital
2022
Nanjing University of Chinese Medicine
2022
Capital Institute of Pediatrics
2022
Bengbu Medical College
2021
The hepatotoxicity of some Chinese herbs has been a cause for concern in recent years. However, herbs, such as rhubarb, have documented having both therapeutic and toxic effects on the liver, leading to complex problem distinguishing benefits from risks using this herb. To comparatively analyze dose-response relationship between rhubarb hepatic health, we administrated total extract (RE) normal carbon tetrachloride (CCl(4))-treated rats 12 weeks at 4 dosage levels (2.00, 5.40, 14.69 40.00...
In contrast to the detailed molecular knowledge available on anthocyanin synthesis, little is known about its catabolism in plants. Litchi (Litchi chinensis) fruit lose their attractive red color soon after harvest. The mechanism leading quick degradation of anthocyanins pericarp not well understood. An enzyme (ADE) was purified homogeneity by sequential column chromatography, using partially from litchi as a substrate. ADE, 116 kD urea SDS-PAGE, identified laccase (ADE/LAC). full-length...
Abstract The Influenza A virus is a great threat for human health, while various subtypes of the made it difficult to develop drugs. With development state-of-art computational chemistry, molecular docking could serve as virtual screen potential leading compound. In this study, we performed influenza H1N1 (A/PR/8/34) with small molecules such quercetin and chlorogenic acid, which were derived from traditional Chinese medicine. results showed that these have strong binding abilities...
For the first time, response surface methodology (RSM) using a Box-Behnken Design (BBD) was employed to optimize conditions for ultrasonic assisted extraction (UAE) of antioxidants from Chinese sumac (Rhus typhina L.) fruits. Initially, influencing factors such as liquid-solid ratio, duration extraction, pH range, temperature and ethanol concentration were identified single-factor experiments. Then, with respect three most significant factors, process focusing on DPPH· scavenging capacity...
A hypoxic environment is generally undesirable for most plants and stimulates anaerobic metabolism. It a beneficial treatment, however, the removal of astringency from persimmon to improve fruit quality after harvest. High soluble tannins (SCTs) content one important causes astringency. CO2 (95%) treatment effectively reduced SCTs in both "Mopan" "Gongcheng-shuishi" by causing increases acetaldehyde. Using RNA-seq realtime PCR, twelve ethylene response factor genes (DkERF11-22) were isolated...
Litchi pericarp turns brown rapidly after fruit harvest, while the mechanism remains obscure. The contents of (-)-epicatechin (EC) and procyanidins (PCs) A2/B1/B2/C1 decreased during browning, a previously identified laccase (ADE/LAC) showed activity to these compounds, with products observed in reactions. By UPLC-DAD-QTOF-MS/MS, isomers dimeric, trimeric, tetrameric PCs were detected EC-ADE/LAC reaction. In presence cyanidin-3-O-rutiside rutin, anthocyanin-EC rutin-EC adducts were,...
Litchi (Litchi chinensis Sonn.) fruit is known for its rich source of phenolics. pericarp contains high levels epicatechin that may form oligomers various lengths. Except several A or B type dimers, other soluble have rarely been identified in the pericarp. Here, bioassay-guided column fractionation was applied to isolate bioactive phenolics from aqueous extract. fraction (S3) obtained by two rounds Sephadex LH-20 chromatography, and showed higher antioxidant activity inhibition on...
Organisms can regulate mitochondrial metabolic adaptation, further ameliorate the energy homeostasis to control ATP production for expenditure during growth process under different physiological and nutritional conditions. Based on this understanding, objective of present study was investigate how dietary n-3 PUFA (polyunsaturated fatty acid) lipid sources modify affect swimming crab ( Portunus trituberculatus ). A total 120 juveniles with an average initial weight 10.17 ± 0.12 g were fed...
Acute myeloid leukemia (AML) represents an aggressive hematopoietic malignancy with a prognosis inferior to that of other leukemias. Recent targeted therapies offer new opportunities achieve better treatment outcomes. However, due the complex heterogeneity AML, its remains dismal. In this study, we first identified correlation between high expression BRD4 and overall survival patients AML. Targeted degradation BRD2, BRD3, proteins by dBET1, proteolysis-targeting chimera (PROTAC) against...
A thiazole-containing cyclic depsipeptide with 11 amino acid residues, named pagoamide (1), was isolated from laboratory cultures of a marine Chlorophyte, Derbesia sp. This green algal sample collected America Samoa, and using guidance by MS/MS-based molecular networking. Cultures were grown in light- temperature-controlled environment harvested after several months growth. The planar structure (1) characterized detailed 1D 2D NMR experiments along MS UV analysis. absolute configurations its...
Angiosperm stigma supports compatible pollen germination and tube growth, resulting in fertilization seed production. Stigmas are mainly divided into two types, dry wet, according to the absence or presence of exudates on their surfaces. Here, we used 2DE MS identify proteins specifically preferentially expressed stigmas maize (Zea Mays, stigma) tobacco (Nicotiana tabacum, wet stigma), as well rinsed from surface stigma. We found that share similar distributions functional categories....
Abstract: A new cyclopentenone, 5-hydroxycyclopeni cillone (1), was isolated together with three known compounds, ar-turmerone (2), citreoisocoumarin (3), and 6-O-methyl-citreoisocoumarin (4), from a culture of the sponge-derived fungus Trichoderma sp. HPQJ-34. The structures 1–4 were characterized using comprehensive spectroscopic analyses. absolute configuration 1 determined by comparison electronic circular dichroism (ECD) spectra literature values used for reported analogue,...
The fruit of Litchi chinensis contains high levels proanthocyanidins (PAs) in the pericarp. These substances can serve as substrates laccase-mediated rapid pericarp browning after is harvested. In this study, we found that major PAs litchi were (-)-epicatechin (EC) and several procyanidins (PCs), primarily PC A2, B2, B1, EC content decreased with development fruit. RNA-seq analysis showed 43 early late structure genes related to flavonoid/PA biosynthesis expressed pericarp, including five...
ABSTRACT “ Candidatus Liberibacter asiaticus” (CLas), the causal agent of citrus Huanglongbing (HLB), is able to multiply a high abundance in fruit pith. However, little known about biological processes and phytochemical substances that are vital for CLas colonization growth In this study, CLas-infected pith three cultivars (“Shatangju” mandarin, “Guanxi” pomelo, “Shatian” pomelo) exhibiting different tolerance were collected used dual RNA-Seq untargeted metabolome analysis. Comparative...
Ionizing radiation can induce DNA damage and cell death by generating reactive oxygen species (ROS). The objective of this study was to investigate the radio-protective effect catalpol (a main bioactive component in traditional Chinese Rehmannia) on irradiated cells mice. We found that treating with (25-100 μg/ml) before irradiation could significantly inhibit ionizing (IR)-induced human lymphocyte AHH-1 apoptosis increase viability vitro. At same time our also showed mg/kg) reduced...
Summary γ‐aminobutyric acid (GABA) has been found accumulating significantly in soybean seeds during germination. However, the mechanism of process is not clear. Therefore, gene expression, enzyme activity and metabolites associated with GABA shunt ZH 13 germination were analysed this paper. content 5‐day germinated was 0.26 ± 0.016 mg g −1 DW , which equivalent to six times concentration original soybean. The GAD a positive effect on accumulation as well ‐T play significant role degradation...