A5014094111- Sociology and Education Studies
- German Social Sciences and History
- Transportation and Mobility Innovations
- Innovation, Technology, and Society
- Pancreatic and Hepatic Oncology Research
- Medieval European History and Architecture
- Public Administration and Political Analysis
- Cancer Genomics and Diagnostics
- Youth Education and Societal Dynamics
- Psychoanalysis and Social Critique
- Digital Innovation in Industries
- Esophageal Cancer Research and Treatment
- Sharing Economy and Platforms
- Urban Transport and Accessibility
- German Literature and Culture Studies
- Persona Design and Applications
- Esophageal and GI Pathology
- Medical and Health Sciences Research
- Metastasis and carcinoma case studies
- Adipose Tissue and Metabolism
- Gastric Cancer Management and Outcomes
- Weber, Simmel, Sociological Theory
- Social and Cultural Dynamics
- Economic and Social Issues
- Children's Rights and Participation
University of Duisburg-Essen
2011-2025
Observatoire de la Côte d’Azur
2020-2024
University Medical Center Hamburg-Eppendorf
2010-2022
Universität Hamburg
2010-2022
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2019-2022
Klinikum Wilhelmshaven
2020-2021
Toronto Rehabilitation Institute
2018
University of Waterloo
2018
University of Toronto
2018
University of Wuppertal
2008-2016
Intestinal inflammation can impair mucosal healing, thereby establishing a vicious cycle leading to chronic inflammatory bowel disease (IBD). However, the signaling networks driving remain unclear. Here we report that CD4+ T cells isolated from patients with IBD produce high levels of interleukin-22 binding protein (IL-22BP), endogenous inhibitor tissue-protective cytokine IL-22. Using mouse models, demonstrate development requires cell-derived IL-22BP. Lastly, intestinal responsive...
In Brief Objectives: Development of a simple preoperative risk score to predict morbidity related pancreatic surgery. Background: Pancreatic surgery is standardized with little technical diversity among institutions and unchanging mortality rates in recent years. Preoperative identification high-risk patients potentially one the rare avenues for improving clinical course undergoing Methods: Using prospectively collected multicenter database (n = 703), surgical complications were classified...
Autonomous mobility on demand systems (AMODS) are predicted to face a bright future for providing convenient individual mobility. Yet, increasing the occupancy rate of AMODS by ridesharing is an essential prerequisite sustainable The online study (N = 150) assessed travelers' willingness share rides with unknown fellow travelers in shared (SAMODS) depending factors travel distance and detour factor that affected scheme. findings reveal great acceptability SAMODS underline importance time...
Colorectal cancer (CRC) is one of the leading causes death worldwide. There an urgent need to identify prognostic markers for patients undergoing curative resection CRC. The detection circulating tumor cells in peripheral blood a promising approach high-risk with disseminated disease colorectal cancer. This study aims evaluate relevance preoperative CTCs using Cellsearch® system (CS) patients, who underwent intent different stages (UICC I-IV) Out 91 Patients resection, 68 were included this...
In most cases, metastatic colorectal cancer is not curable, thus new approaches are necessary to identify novel targets for therapy. Actin‐binding‐proteins (ABPs) directly regulate motility of metastasising tumor cells, and cortactin an association with colon metastasis has been already shown. However, as its depletion only incompletely inhibits metastasis, additional, more suitable cellular have be identified. Here we analyzed expression the ABPs, DIAPH1, VASP, N‐WASP, fascin in comparison...
Shared on-demand mobility services emerge at a fast pace, changing the landscape of public transport. However, shared are largely designed without considering access needs people with disabilities, putting these passengers risk exclusion. Recognising that accessibility is best addressed design stage and through direct participation persons objective this study was to explore disabled users' views on following emerging services: (a) ride pooling, (b) microtransit, (c) motorbike taxis, (d)...
ABSTRACT Neisseria meningitidis , the causative agent of meningitis and septicemia, is able to attach invade a variety cell types. In previous study we showed that entry N. into human brain microvascular endothelial cells (HBMEC) mediated by fibronectin bound outer membrane protein Opc, which forms molecular bridge α5β1-integrins. This interaction results in cytoskeletal remodeling uptake bacteria. this identified characterized intracellular signals involved integrin-initiated . We...
Abstract BACKGROUND Genomic information can help to identify colorectal tumors with high and low metastatic potential, thereby improving prediction of benefit local and/or systemic treatment. Here we investigated chromosomal aberrations in relation the different stages cascade: dissemination tumor cells into mesenteric vein, outgrowth liver, intravasation peripheral blood circulation, development further distant metastasis. METHODS Peripheral from cancer patients (n = 72) were for...
The biographies of individuals in today’s societies are characterized by the need to exert effort and make decisions planning one’s life course. A ‘self-project’ has be worked out both retrospectively prospectively; childhood becomes important as a resource laboratory for self-project. This empirical study analyses how occupational choices young people connected with their aspirations child. Children’s prove class-sensitive. Studying importance self-project thus makes it possible consider...
This article outlines the ways in which clothing is one important medium for presentation of self, on basis interviews and group discussions with young people a qualitative study. In process leaving their childhood behind, have to present themselves as individuals; self has be indicated an individualized (and unequal) society. Their vestimentary practices are both bound by social order also contribute its constitution. The develops critical discussion generational order, simultaneously class...