Marie Irlès-Depé
A5085390583- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Inflammatory Bowel Disease
- Diet, Metabolism, and Disease
- Cannabis and Cannabinoid Research
- Autoimmune and Inflammatory Disorders
- Gastrointestinal Tumor Research and Treatment
- Diverticular Disease and Complications
- Advanced MRI Techniques and Applications
- Eosinophilic Esophagitis
- Microscopic Colitis
- Alcohol Consumption and Health Effects
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Viral gastroenteritis research and epidemiology
- Radiomics and Machine Learning in Medical Imaging
- Ultrasound Imaging and Elastography
- Pancreatitis Pathology and Treatment
- Medical Imaging Techniques and Applications
- Gastrointestinal disorders and treatments
Hôpital Cardiologique du Haut-Lévêque
2018-2023
Centre Hospitalier Universitaire de Bordeaux
2018-2022
Inserm
2021-2022
Université de Bordeaux
2021-2022
SomaLogic (United States)
2022
Institut Universitaire de Recherche Clinique
2022
Bordeaux Population Health
2021
Hôpital Pellegrin
2020
KU Leuven
2018
Background and Aims: The European Association for the Study of Liver (EASL) has recently proposed an algorithm diagnosis advanced liver fibrosis. We aimed to evaluate diagnostic accuracy this in nonalcoholic fatty disease (NAFLD). Approach Results: One thousand fifty‐one patients with NAFLD, biopsy, four noninvasive tests (NITs; Fibrosis‐4 [FIB4], vibration controlled transient elastography [VCTE], FibroMeter, Fibrotest) were included. enhanced fibrosis (ELF) score was available 396...
The combination of laboratory and elastography tests allows the accurate diagnosis advanced liver fibrosis in patients with NAFLD. In this study, we compared diagnostic performances a two-step strategy (laboratory vibration-controlled transient [VCTE] or two-dimensional shear-wave SuperSonic Imagine [2D-SWE-SSI]) added value three-step two methods).From prospective registry, retrospectively selected 577 consecutive suspicion NAFLD who underwent to calculate Fibrosis-4 (FIB-4) score,...
The boundary between non-alcoholic (NAFLD) and alcohol-related liver disease (ALD) is based on alcohol consumption. However, metabolic syndrome use frequently co-exist. aim of this study was to determine prognostic factors long-term morbidity mortality in patients with NAFLD or ALD.From 2003 2016, all consecutive ALD were prospectively included cohort study. We evaluated overall survival, specific cause occurrence any complication. primary endpoint analysed by the Kaplan Meier method,...
Unlike for advanced liver fibrosis, the practical rules early non-invasive diagnosis of cirrhosis in NAFLD remain not well defined. Here, we report derivation and validation a stepwise diagnostic algorithm 1568 patients with biopsy coming from four independent cohorts. The study algorithm, using first elastography-based tests Agile3+ Agile4 then specialized blood FibroMeterV3G CirrhoMeterV3G, provides stratification groups, last which is enriched (71% prevalence set). A risk prediction chart...
Non-invasive assessment of fibrosis is predictive the prognosis non-alcoholic and alcoholic fatty liver disease but this has not been demonstrated in metabolic (dysfunction)-associated (MAFLD).We assessed non-invasive methods patients with MAFLD.All consecutive MAFLD, stiffness measurements, FIB-4 (Fibrosis-4), LIVERFASt were included cohort study. The primary endpoint was analysed by Kaplan-Meier method secondary endpoints estimated Gray test or logistic regression. Factors independently...
Approximately 80% of patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), and its effect on the outcomes liver transplantation (LT) for PSC is unclear. We retrospectively collected data from adults who underwent LT 1989 to January 2018 in 4 French centers. compared rates patient graft survivals complications after LT. Among 87 patients, 52 (60%) had preexisting IBD. Excluding those died within first 3 months, 10‐year survival were 92.6% (95%...
Background: Chronic hepatitis B virus (HBV) infection may evolve into cirrhosis and hepatocellular carcinoma, this progression be accelerated by specific risk factors, including overweight obesity. Although evidence for a protective effect of cannabis use on elevated body weight has been found other populations, no data are available HBV-infected patients. Aims: We aimed to identify factors (including use) obesity in patients with HBV chronic infection. Methods: Using baseline from the...
The Rutgeerts’ score (RS) is used to guide management of patients with Crohn’s disease (CD) after ileal resection ileo-colonic anastomosis. modified RS differentiates lesions at the anastomosis ±<5 isolated neo-terminal erosions (i2a) from presence ≥5 ± anastomotic (i2b). We investigated if clinical relapse (CR) and need for new endoscopic/surgical intervention (NI) differ between i2a i2b endoscopic recurrence (ER). Our secondary objective was evaluate effect therapy modification based on...
Patients with chronic hepatitis C virus (HCV) infection are at greater risk of developing metabolic disorders. Obesity is a major factor for these disorders, and therefore, managing body weight crucial. Cannabis use, which common in patients, has been associated lower corpulence various populations. However, this relationship not yet studied persons HCV infection.Using baseline data from the French ANRS CO22 Hepather cohort, we used binary logistic multinomial regression models to test an...
Background: Screening T2DM for NASH fibrosis using specific markers is mandatory, as liver enzymes are often normal despite advanced fibrosis. LIVERFASt (LF), a serum marker with CPT code assessing (LF-Fib), activity and steatosis had high performance identifying severe in T2DM.Aim: To demonstrate that LF-Fib an alternative to biopsy (LB) the estimation of transition rate [F1 stage or more (TRF1)], NAFLD better performances than transient elastography (TE) FIB4.Methods: TRF1 was evaluated...