Linda T. Betz
A5037207804- Schizophrenia research and treatment
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Bipolar Disorder and Treatment
- Neuroscience and Music Perception
- Neural and Behavioral Psychology Studies
- Attention Deficit Hyperactivity Disorder
- Child Abuse and Trauma
- Cannabis and Cannabinoid Research
- Personality Disorders and Psychopathology
- Advanced Neuroimaging Techniques and Applications
- Digital Mental Health Interventions
- Olfactory and Sensory Function Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Psychotherapy Techniques and Applications
- Bullying, Victimization, and Aggression
- Innovation in Digital Healthcare Systems
- Personality Traits and Psychology
- Cognitive Abilities and Testing
- Technology and Data Analysis
- Telemedicine and Telehealth Implementation
GAIA (Germany)
2024-2025
University of Bari Aldo Moro
2020-2024
University Hospital Cologne
2019-2023
University of Cologne
2020-2023
Ludwig-Maximilians-Universität München
2018-2020
University of Regensburg
2017
Abstract Recent life events have been implicated in the onset and progression of psychosis. However, psychological processes that account for association are yet to be fully understood. Using a network approach, we aimed identify pathways linking recent symptoms observed Based on previous literature, hypothesized general would mediate between psychotic symptoms. We analyzed baseline data patients at clinical high risk psychosis with recent-onset ( n = 547) from Personalised Prognostic Tools...
Abstract Background Hypertension is a major public health problem. Despite existing treatment options, overall blood pressure control still insufficient. Digital interventions have the potential to improve success. We developed liebria , an internet-based digital intervention accessible via smartphones and computers, designed support self-management of hypertension. Methods tested effectiveness in reducing systolic improving other relevant endpoints adults with hypertension using parallel...
Abstract Background Experiences of childhood trauma (CT) are associated with increased psychological vulnerability. Past research suggests that CT might alter stress processing a subsequent negative impact on mental health. However, it is currently unclear how different domains exert effects specific subjective experiences during adulthood. Methods In the present study, we used network analysis to explore complex interplay between distinct and perceived in large, general-population sample...
Abstract In schizophrenia, neurocognitive subtypes can be distinguished based on cognitive performance and they are associated with neuroanatomical alterations. We investigated the existence of in shortly medicated recent onset psychosis patients, their underlying gray matter volume patterns clinical characteristics. used a K-means algorithm to cluster 108 patients from multi-site EU PRONIA (Prognostic tools for early management) study validated solution independently ( N = 53). Cognitive...
Abstract Tinnitus is primarily an auditory symptom. Yet not only patients and clinicians, but also current pathophysiological models relate the onset maintenance of tinnitus to stress. Here physiological psychological stress reactivity was investigated in 19 with subjective chronic comparable healthy controls. All participants underwent five consecutive measurements one session including three resting conditions two tasks between (mental arithmetic concentration on tinnitus/ear noise)....
Abstract Increased mental health literacy (MHL) has not reduced stigmatization of people with disorder. Thus, we examined the role stereotypes in interplay MHL (correct labelling, causal explanations) and wish for social distance (WSD) from depressive psychotic symptoms a community sample 1526 German-speaking participants Swiss ‘Bern Epidemiological At-Risk’ study (age 16–40 years; response rate: 60.1%). Following presentation an unlabelled case vignette depression or psychosis, MHL, WSD...
Abstract Cognitive behavioral therapy improves psychosocial outcomes in rheumatoid arthritis (RA), but access is limited. We conducted a randomized controlled trial to evaluate the efficacy of cognitive-behavioral digital therapeutic, reclarit , on adult RA patients with impaired health-related quality life. Participants were plus treatment as usual (TAU) or TAU educational and informational material (active control). The primary outcome was SF-36 mental (MCS) physical (PCS) component...
Abstract Cannabis use during adolescence is associated with an increased risk of developing psychosis. According to a current hypothesis, this results from detrimental effects early cannabis on brain maturation vulnerable period. However, studies investigating the interaction between and structural alterations hitherto reported inconclusive findings. We investigated age initiation psychosis using data multicentric Personalized Prognostic Tools for Early Psychosis Management (PRONIA) Induced...
Abstract Cognitively impaired and spared patient subgroups were identified in psychosis depression, clinical high-risk for (CHR). Studies suggest differences underlying brain structural functional characteristics. It is unclear whether cognitive are transdiagnostic phenomena early stages of psychotic affective disorder which can be validated on the neural level. Patients with recent-onset (ROP; N = 140; female 54), depression (ROD; 130; 73), CHR ( 128; 61) healthy controls (HC; 270; 165)...
Abstract Schizotypy constitutes a susceptibility to beneficial and deleterious schizotypal traits, ranging from coping mechanisms personality disorder on psychosis continuum. Growing evidence indicates relationship between childhood adversity trauma schizotypy. However, the exact influence of schizotypy its relation sex is not sufficiently understood. Therefore, we investigated sex-adjusted connections subdomains (emotional/physical/sexual abuse, emotional/physical neglect) positive (magical...
Abstract Background Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease with diverse symptomatology, significantly impacting patients’ quality of life (QoL). While pharmacological therapies focus primarily on reducing inflammation and relapse rates, non-pharmacological interventions, including digital health applications, have shown promise in improving QoL among persons MS (PwMS). Pilot studies had the feasibility acceptability levidex , application based cognitive...
Abstract Cognitive gains following cognitive training interventions are associated with improved functioning in people schizophrenia (SCZ). However, considerable inter-individual variability is observed. Here, we evaluate the sensitivity of brain structural features to predict functional response auditory-based (ABCT) at a single-subject level. We employed whole-brain multivariate pattern analysis support vector machine (SVM) modeling identify gray matter (GM) patterns that predicted higher...
Abstract Cannabis use characteristics, such as earlier initiation and frequent use, have been associated with an increased risk for developing psychotic experiences disorders. However, little is known how these characteristics relate to specific aspects of sub-clinical psychopathology in the general population. Here, we explore relationships between cannabis a large population sample ( N = 2,544, mean age 29.2 years, 47% women) by employing network approach. This allows identification unique...
Prevention in psychiatry provides a promising way to address the burden of mental illness. However, established approaches focus on specific diagnoses and do not heterogeneity manifold potential outcomes help-seeking populations that present at early recognition services. Conceptualizing psychopathology manifested from network perspective interacting symptoms allows transdiagnostic investigations beyond binary disease categories. Furthermore, modern technologies such as smartphones...
Psychosis and depression patients exhibit widespread neurobiological abnormalities. The analysis of dynamic functional connectivity (dFC), allows for the detection changes in complex brain activity patterns, providing insights into common unique processes underlying these disorders. In present study, we report dFC a large patient sample including 127 clinical high-risk (CHR), 142 recent-onset psychosis (ROP) patients, 134 (ROD) 256 healthy controls (HC). A sliding window-based technique was...