Carolina Bonivento
A5043835253- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Autism Spectrum Disorder Research
- Advanced Neuroimaging Techniques and Applications
- Action Observation and Synchronization
- Psychosomatic Disorders and Their Treatments
- Attention Deficit Hyperactivity Disorder
- Treatment of Major Depression
- Genetics and Neurodevelopmental Disorders
- Personality Disorders and Psychopathology
- Maternal Mental Health During Pregnancy and Postpartum
- Neurobiology of Language and Bilingualism
- Neuroscience and Music Perception
- Child Abuse and Trauma
- Motor Control and Adaptation
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Birth, Development, and Health
- Mental Health and Psychiatry
- Advanced MRI Techniques and Applications
IRCCS Eugenio Medea
2012-2024
University Hospital Cologne
2024
Authorised Association Consortium
2022-2024
University of Cologne
2024
University of Milan
2022-2023
Politecnico di Milano
2023
Ludwig-Maximilians-Universität München
2023
University of Udine
2016-2022
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2022
University of Birmingham
2012-2014
Although the study of neuroanatomical correlates generalized anxiety disorder (GAD) is gaining increasing interest, up to now cortical anatomy GAD patients has been poorly investigated and still no data on gyrification are available. The aim present quantitatively examine morphology in with compared healthy controls (HC) using magnetic resonance imaging (MRI). To best our knowledge, this first analyzing patterns GAD.A total 31 HC underwent 3 T structural MRI. For each subject, surface area...
Studies investigating cognitive impairments in psychosis and depression have typically compared the average performance of clinical group against healthy controls (HC), do not report on actual prevalence or strengths within these groups. This information is essential so that services can provide adequate resources to supporting functioning. Thus, we investigated this individuals early course depression.A comprehensive test battery comprising 12 tests was completed by 1286 aged 15-41 (mean...
Abstract Diagnostic heterogeneity within and across psychotic affective disorders challenges accurate treatment selection, particularly in the early stages. Delineation of shared distinct illness features at phenotypic brain levels may inform development more precise differential diagnostic tools. We aimed to identify prototypes depression psychosis investigate their heterogeneity, with common, comorbid transdiagnostic symptoms. Analyzing clinical/neurocognitive grey matter volume (GMV) data...
Approaches are needed to stratify individuals in early psychosis stages beyond positive symptom severity investigate specificity related affective and normative variation validate solutions with premorbid, longitudinal, genetic risk measures.
Abstract In schizophrenia, neurocognitive subtypes can be distinguished based on cognitive performance and they are associated with neuroanatomical alterations. We investigated the existence of in shortly medicated recent onset psychosis patients, their underlying gray matter volume patterns clinical characteristics. used a K-means algorithm to cluster 108 patients from multi-site EU PRONIA (Prognostic tools for early management) study validated solution independently ( N = 53). Cognitive...
Autism spectrum disorder (ASD) is a neurodevelopmental condition with heterogeneous phenotype. The role of biomarkers in ASD diagnosis has been highlighted; cortical thickness proved to be involved the etiopathogenesis core symptoms. We apply support vector machine, supervised machine learning method, order identify specific alterations subjects.
Researchers' interest have recently moved toward the identification of recurrent psychopathological profiles characterized by concurrent elevations on different behavioural and emotional traits. This new strategy turned to be useful in terms diagnosis outcome prediction. We used a person-centred statistical approach examine whether groups could identified referred sample general-population children adolescents, we investigated their relation DSM-IV diagnoses. A latent class analysis (LCA)...
Impulsivity has been proposed as an endophenotype for bipolar disorder (BD); moreover, impulsivity levels have shown to carry prognostic significance and be quality-of-life predictors. To date, reports about the genetic determinants of in mood disorders are limited, with no studies on BD individuals. Individuals healthy controls (HC) were recruited context observational, multisite study (GECOBIP). Subjects genotyped three candidate single-nucleotide polymorphisms (SNPs) (5-HTTLPR, COMT...
Abstract Cognitively impaired and spared patient subgroups were identified in psychosis depression, clinical high-risk for (CHR). Studies suggest differences underlying brain structural functional characteristics. It is unclear whether cognitive are transdiagnostic phenomena early stages of psychotic affective disorder which can be validated on the neural level. Patients with recent-onset (ROP; N = 140; female 54), depression (ROD; 130; 73), CHR ( 128; 61) healthy controls (HC; 270; 165)...
The ability to reproduce visually presented actions has been studied through neuropsychological observations of patients with ideomotor apraxia. These studies include attempts understand the neural basis action reproduction based on lesion–symptom mapping in different patient groups. While there is a convergence evidence that areas parietal and frontal lobes within left hemisphere are involved imitation variety actions, questions remain about whether results generalize beyond tool use...
Abstract Mental imagery is part of people's own internal processing and plays an important role in everyday life, cognition pathology. The neural network supporting mental bottom‐up modulated by the content. Here, we examined complex associations gender age with mechanisms underlying emotion imagery. We assessed brain circuits involved (vs. action imagery), controlled a letter detection task on same stimuli, chosen to ensure attention stimuli discourage imagery, 91 men women aged 14–65 years...
<b><i>Background:</i></b> Bipolar disorder (BD) has been associated with temperamental and personality traits, although the relationship is still to be fully elucidated. Several studies investigated genetic basis of temperament character, identifying catechol-O-methyltransferase (COMT), brain derived neurotrophic factor (BDNF), serotonin transporter (5-HTT) gene variants as strong candidates. <b><i>Methods:</i></b> In GECO-BIP study, 125 BD...
Language production has often been described as impaired in psychiatric diseases such psychosis. Nevertheless, little is known about the characteristics of linguistic difficulties and their relation with other cognitive domains patients a first episode psychosis (FEP), either affective or non-affective. To deepen our comprehension profile FEP, 133 FEP (95 non-affective, FEP-NA; 38 affective, FEP-A) healthy controls (HC) were assessed narrative discourse task. Speech samples systematically...
Neurocognitive deficits are a core feature of psychosis and depression. Despite commonalities in cognitive alterations, it remains unclear if how the patients at clinical high risk for (CHR) those with recent-onset (ROP) distinct from seen depression (ROD).This study was carried out within European project 'Personalized Prognostic Tools Early Psychosis Management', aimed to characterise profiles or depression.We examined ROP (n = 105), ROD 123), CHR 116) healthy controls 372) across seven...