A5100667286- Psoriasis: Treatment and Pathogenesis
- Rabies epidemiology and control
- Intracerebral and Subarachnoid Hemorrhage Research
- Pediatric health and respiratory diseases
- Medical Device Sterilization and Disinfection
- NF-κB Signaling Pathways
- T-cell and B-cell Immunology
- Streptococcal Infections and Treatments
- Acute Myocardial Infarction Research
- Autoimmune Bullous Skin Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Viral Infections and Outbreaks Research
- Vector-borne infectious diseases
- Neurological Disease Mechanisms and Treatments
- Viral Infections and Vectors
- Immune Response and Inflammation
- Venomous Animal Envenomation and Studies
- Cutaneous lymphoproliferative disorders research
- Acute Ischemic Stroke Management
- Vector-Borne Animal Diseases
- Immunodeficiency and Autoimmune Disorders
- Advanced Technologies in Various Fields
- Autoimmune and Inflammatory Disorders Research
- Dermatology and Skin Diseases
- Immune Cell Function and Interaction
Second Affiliated Hospital of Xi'an Jiaotong University
2022-2025
Hetao College
2023
Creative Commons
2022
Nanjing Medical University
2019
Jiangsu Province Hospital
2019
Yuncheng Central Hospital
2018
Shanxi Medical University
2018
Yuncheng University
2018
Anhui Medical University
2015-2017
Fujian Medical University
2006
Abstract Background: Generalized pustular psoriasis (GPP), a rare and recurrent autoinflammatory disease, imposes substantial burden on patients society. Awareness of GPP in China remains limited. Methods: This cross-sectional survey, conducted between September 2021 May 2023 across 14 hospitals China, included all ages disease phases. Data collected encompassed demographics, clinical characteristics, economic impact, severity, quality life, treatment-related complications. Risk factors for...
ObjectivesTo evaluate the immunogenicity and safety of an anti-rabies monoclonal antibody (mAb), ormutivimab, compared with human rabies immunoglobulin (HRIG).MethodsThis phase III trial was designed as a randomized, double-blind, non-inferiority clinical in patients aged ≥18 years suspected World Health Organization category Ⅲ exposure. The participants were randomized 1:1 to ormutivimab HRIG groups. After thorough wound washing injection ormutivimab/HRIG on day 0, vaccination administered...
Chronic obstructive pulmonary disease (COPD) and tuberculosis (PTB) share a number of common risk factors, including innate immunity-related genetic factors. In the present study, we compared role variations TLR4 gene in susceptibility to COPD PTB illuminated underlying molecular mechanism functional single-nucleotide polymorphisms (SNPs).A population-based case control study was performed Chinese Han population included 152 cases, 1601 cases 1727 controls. Five SNPs (rs10759932, rs2737190,...
Tick-borne infectious diseases pose a serious health threat in certain regions of the world. Emerging caused by novel tick-borne pathogens have been reported that are causing particular concern. Several often coexist same foci, and single vector tick can transmit two or more at time, which greatly increases probability co-infection host animals humans lead to an epidemic disease. The lack epidemiological data information on specific clinical symptoms related with means it is not currently...
Passive immune agents play an important role in the prevention of rabies following exposure. This trial investigated safety, tolerability, and pharmacokinetics recombinant human monoclonal antibodies against virus (rhRIG). clinical was conducted on healthy Chinese adults. The subjects were enrolled into three dosage groups. safety drug assessed, blood concentration antibody (NM57) neutralizing levels measured. rhRIG presented favorable tolerability.The low(10 IU/kg), medium(20 high(40 IU/kg)...
Objective: This study was performed to investigate the clinical characteristics of patients with generalized pustular psoriasis (GPP) in Northwest China. Methods: The data GPP were retrospectively collected Second Affiliated Hospital Xi’an Jiaotong University from January 1, 2017, December 31, 2021 and analyzed using chi-square test Mann-Whitney U test. Results: In total, 179 hospitalized included. male:female ratio 1.16:1.00, mean age at onset 35.05 ± 19.11 years. Psoriasis vulgaris also...
Objective To study the value of expanded-National Institutes Health Stroke Scale (e-NIHSS) in evaluating neurological signs medullary infarction. Methods One hundred and thirteen patients with primary infarction proved by magnetic resonance imaging were enrolled divided into medial (MMI) group (n=41) lateral (LMI) (n=72). Risk factors stroke evaluated NIHSS e-NIHSS recorded compared between two groups. Results The age prevalence diabetes MMI significantly older/higher than those...
Objective To study the relationship between decline of ST segment electrocardiogram and prognosis in acute myocardial infarction(AMI) patients after percutaneous coronary intervention(PCI) treatment. Methods Two hundred with infarction treated our hospital from June 2016 to 2017 were selected as subjects. The divided into two groups according their status treatment, 100 cases each group. total elevation group A decreased by more than 50% that B less treatment. occurrence rate adverse...