A5100767242- Renal cell carcinoma treatment
- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bladder and Urothelial Cancer Treatments
- Cellular Mechanics and Interactions
- Pediatric Urology and Nephrology Studies
- Erythrocyte Function and Pathophysiology
- Kidney Stones and Urolithiasis Treatments
- Nanoplatforms for cancer theranostics
- Mast cells and histamine
- Cancer Research and Treatments
- Immunotherapy and Immune Responses
- Urinary Tract Infections Management
- Advanced Battery Technologies Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer, Lipids, and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Eicosanoids and Hypertension Pharmacology
- Extracellular vesicles in disease
- Advanced Algorithms and Applications
- Virus-based gene therapy research
- Blood Pressure and Hypertension Studies
- Urinary and Genital Oncology Studies
- Asthma and respiratory diseases
- Tracheal and airway disorders
Huazhong University of Science and Technology
2008-2024
Tongji Hospital
2008-2024
Meizhou City People's Hospital
2024
Qingdao University
2023-2024
Affiliated Hospital of Qingdao University
2024
Shanghai Center for Brain Science and Brain-Inspired Technology
2024
China-Japan Friendship Hospital
2024
Cuproptosis is a newly recognized copper-dependent nonapoptotic form of cell death, which stimulate studies exploring copper-based nanomaterials to treat cancer through distinct mechanistic action. However, it remains challenge completely eradicate tumors via monotherapy. Herein, copper-doped BiSex (CBS) nanozyme was developed boost αPD-L1-mediated immune checkpoint blocking (ICB) synergetic apoptosis/cuproptosis-induced immunogenic death (ICD). The defect-engineered CBS exhibits strong...
Abstract Objective Dyslipidemia is a co-existing problem in patients with diabetes mellitus (DM) and coronary artery disease (CAD), apolipoprotein E (APOE) plays an important role lipid metabolism. However, the relationship between APOE gene polymorphisms risk of developing CAD type 2 DM (T2DM) remains controversial. The aim this study was to assess provide reference for further assessment T2DM patients. Methods included 378 complicated (T2DM + CAD) 431 alone case group, 351 individuals...
The purpose of this study was to assess risk factors urosepsis after minimally invasive percutaneous nephrolithotomy (MPCNL) for the treatment upper urinary tract stones in patients with preoperative infection (UTI) and explore preventive measures. Between 2008 2016, UTI who underwent MPCNL were retrospectively collected. Patients divided into nonurosepsis groups. Perioperative outcomes all evaluated compared between two Risk post-MPCNL investigated using univariate multivariate regression...
Repeat partial nephrectomy (PN) is an effective treatment in improving the prognosis for patients with recurrent renal cancer after initial PN. However, salvage PN (sPN) inevitably associated a higher rate of complications, largely because intraperitoneal adhesions and fibrosis. Here we describe three cases which tumors were treated novel minimally invasive approach, namely Ultrasound-guided Renal Artery Balloon catheter Occluded Hybrid Partial Nephrectomy (UBo-HPN).With laparoscopic...
Accurately estimating the state of charge (SOC) is crucial for energy storage battery management systems as it ensures performance and extends lifespan. However, existing deep learning-based methods often overlook dynamic process information during charging discharging, which compromises accuracy SOC estimation. To address this limitation, paper proposes a novel estimation method. First, we employ differential processing on collected voltage, current, temperature data to capture feature...
One key focus of partial nephrectomy is preserving renal function. Segmental artery occlusion with microdissection at the hilum confines ischemia, effectively reducing warm ischemic injury. Ultrasound-Guided Renal Artery Balloon Catheter Occluded Hybrid Partial Nephrectomy (UBo-HPN) can achieve branch without need for dissecting hilum.
The dorsal root ganglion (DRG) is characterized by the dense clustering of primary sensory neuron bodies, with their axons extending to target tissues for perception. close physical proximity DRG neurons facilitates integration and amplification somatosensation, ensuring normal physiological functioning. However, mechanism underlying aggregation was unclear. In our study, we culture from newborn rats on substrates varying stiffness observe that influenced mechanical signals arising substrate...
Objective: Cytochrome P450 2C19 (CYP2C19) is a major enzyme involved in the biotransformation and metabolism of various substances. Loss-of-function CYP2C19 gene represents downregulation indication limited or no enzymatic function, which may be, turn, associated with some disease susceptibility. The relationship between polymorphisms susceptibility to premature coronary artery (PCAD) not fully understood. This study aimed assess this relationship. Methods: included 635 PCAD patients, 548...
Abstract To explore the of Qufeng Tongqiao Prescription in treatment cerebral ischemia–reperfusion (CIR) and associated molecular network mechanism. Venny diagram, gene ontology (GO) kyoto encyclopedia genes genomes (KEGG) analysis, protein–protein interaction (PPI), hub mining, docking, combined with animal experiments Nissl stain were performed to determine mechanism for CIR treatment. Fifty three intersecting between ischemia reperfusion acquired from analysis. GO analysis showed that...
Objectives Medical research continues to be extensively devoted investigating the pathogenesis and treatment approaches of hereditary renal cancer. By aspect including researchers, institutions, countries, journals, keywords, we conduct a bibliometric analysis literature pertaining cancer over last 23 years. Methods From Web Science Core Collection, conducted search for publications published between January 1, 2000 November 28, 2023. Reviews original articles were included. Results A...
Despite medical interventions, the regenerative capacity of peripheral nervous system is limited. Dorsal root ganglion (DRG) neurons possess to detect mechanical signals from their microenvironment, but impact and mechanism by which these regulate axon regrowth even regeneration in DRG remain unclear. In this study, newborn rats are cultured on substrates with varying degrees stiffness vitro investigate role regrowth. The findings reveal that substrate plays a crucial regulating regrowth, an...
Objective: This study aimed to investigate the inhibitory effect of calcium channel blocker verapamil on human airway sarcomeric fibroblasts through network pharmacology molecular docking combined with experimental validation, so as provide a theoretical and basis for clinical use blockers against benign stenosis. Methods: The relevant targets verapamil, injury, sarcoidosis fibroblast were collected intersected by public database, respectively. protein-protein interaction was constructed...