A5011623917- Inflammasome and immune disorders
- Soybean genetics and cultivation
- Spectroscopy and Chemometric Analyses
- Legume Nitrogen Fixing Symbiosis
- Invertebrate Immune Response Mechanisms
- NF-κB Signaling Pathways
- Identification and Quantification in Food
- Plant biochemistry and biosynthesis
- Polysaccharides and Plant Cell Walls
- Urban Transport and Accessibility
- Membrane-based Ion Separation Techniques
- Aquaculture disease management and microbiota
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Plant pathogens and resistance mechanisms
- Natural product bioactivities and synthesis
- Seaweed-derived Bioactive Compounds
- Essential Oils and Antimicrobial Activity
- Plant Micronutrient Interactions and Effects
- Liver physiology and pathology
- Advanced Chemical Sensor Technologies
- Fuel Cells and Related Materials
- Extraction and Separation Processes
- Plant Stress Responses and Tolerance
- Laser-induced spectroscopy and plasma
Wenzhou Medical University
2011-2024
Fujian Medical University
2024
Shenyang Agricultural University
2024
University of Science and Technology of China
2024
Anhui Agricultural University
2024
Wenzhou Vocational College of Science and Technology
2024
Wenzhou University
2017-2023
Jinan University
2022
Jiangxi Agricultural University
2022
Zhejiang University of Technology
2021
Abstract Background Long non-coding RNAs (lncRNAs) are important epigenetic regulators, which play critical roles in diverse physiological and pathological processes. However, the regulatory mechanism of lncRNAs lung carcinogenesis remains elusive. Here, we characterized a novel oncogenic lncRNA, designated as Lung Cancer Associated Transcript 3 (LCAT3). Methods We predicted validated LCAT3 by analyzing RNA-sequencing (RNA-seq) data cancer tissues from TCGA. Methylated RNA...
Pericarpium citri reticulatae (PCR) is the dried mature fruit peel of
Effects of H2S on seed germination under chromium (Cr) stress were investigated in wheat (Triticum aestivum L.). Under Cr stress, the percentage seeds decreased, but this decrease could be alleviated by pretreatment with NaHS, an donor, a dose-dependent manner. Furthermore, NaHS significantly enhanced activities amylase, esterase, superoxide dismutase, catalase, ascorbate peroxidase, and guaiacol peroxidase Cr-stressed germinating seeds, whereas reduced Cr-induced increase lipoxygenase...
Plant cold acclimation (CA) is a genetically complex phenomenon involving gene regulation and expression. Little known about the cascading pattern of regulatroy network link between genes metabolites during CA. Dendrobium officinale (DOKM) an important medicinal ornamental plant hypersensitive to low temperature. Here, we used large scale metabolomic transcriptomic technologies reveal response CA in DOKM seedlings based on physiological profile analyses. Lowering temperature from 4 -2°C...
Abstract Plant JASMONATE ZIM‐DOMAIN (JAZ) genes play crucial roles in regulating the biosynthesis of specialized metabolites and stressful responses. However, understanding JAZs controlling these biological processes lags due to numerous JAZ copies. Here, we found that two leaf‐specific CwJAZ4/9 from Curcuma wenyujin are strongly induced by methyl‐jasmonate (MeJA) negatively correlated with terpenoid biosynthesis. Yeast two‐hybrid, luciferase complementation imaging vitro pull‐down assays...
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized imbalance, intestinal epithelial mucosal damage, and dysbiosis of the gut microbiota. Polygonatum cyrtonema polysaccharides (PCPs) can regulate microbiota inflammation. Here, different doses PCPs were administered to dextran sodium sulfate-induced UC mice, effects whole compared with those fractionated fractions PCP-1 (19.9 kDa) PCP-2 (71.6 4.2 kDa). Additionally, an antibiotic cocktail was mice deplete microbiota,...
Endoplasmic reticulum (ER) stress-induced cancer cell apoptosis has become a novel signaling target for development of therapeutic drugs. Curcumin exhibits growth-suppressive activity against variety cells. We previously synthesized series monocarbonyl analogues curcumin with strong cytotoxicity tumor In this study, we found that only compound 19 [(1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one] can induce C/EBP-homologous protein (CHOP) expression in human lung H460 Treatment...
We recently reported that H 2S could significantly promote the germination of wheat grains subjected to aluminum (Al(3+)) stress.1 In these experiments seeds were pretreated with donor NaHS for 12 h prior Al(3+) stress. During this pre-incubation period we observed H2S increased activity grain amylase in absence Al(3+). Using embryoless half now show preferentially affects endosperm β-amylase and α-amylase synthesis is unaffected by treatment.
Abstract Hepatic stellate cells (HSCs) were activated and secreted excessive amounts of extracellular matrix (ECM) proteins during pathogenetic progress liver fibrosis. Germacrone (GMO) miR-29b can play an important role in inhibiting growth HSCs production type I collagen. GMO co-encapsulated into nanoparticles (NPs) based on poly(ethylene glycol)-block-poly(lactide-co-glycolide) (PEG-PLGA). Then, NPs modified with cyclic RGD peptides (cRGDfK). cRGDfK is effective ligand to bind integrin α...
Liver fibrosis is a primary threat to public health, owing limited therapeutic options. Germacrone (GM) has been shown exert various curative effects against human diseases, including liver injury. The aim of this study was investigate the pharmacological GM in pathophysiology hepatic and determine its potential mechanisms action. A rat model established via carbon tetrachloride (CCl4 ) treatment, LX-2 cells were stimulated with TGF-β1. on relationship phosphatidylinositol 3-kinase...
Abstract Two polysaccharides were obtained from dandelion roots (DPR) and leaves (DPL) via water extraction ethanol precipitation. Both DPR DPL an acid heteropolysaccharide, with a molecular weight of 5.89 × 10 4 28.2 Da, respectively. Monosaccharide composition results showed that both contained Man, Glc, Rha, GalA, Gal, Ara molar ratios 2.98:1.00:3.67:6.41:2.98:16.70:2.48 1.23:1.00:1.06:5.74:2.88:8.59:1.84, Methylation NMR analysis DPL, triple-helix conformations, mainly composed 4-ɑ-Gal p...
Abstract As NF ‐κB signaling pathway is constitutively activated in lung cancer, targeting has a potential for the treatment. EF 24 been proved to be inhibitor with good antitumor activity, while whose toxicity possibly became one of obstacles enter into clinical application. In order find high efficiency and low inhibitors, was modified 13d screened out. It that possessed an effective combination inhibiting showing lower cytotoxicity on normal cells as well less acute experiment compared...
In order to achieve better results of human complex activity recognition, the optimal feature representation activities from sensor data are studied. Features multiple sets that obtained by learned networks, manual extraction, and location information fused generate mixed features recognition. A method extracting multi-layer hybrid CNN BLSTM network is proposed. The output vector second layer combined features. Meanwhile, a new selection based on SFS weight analysis select series extracted...