- Chromosomal and Genetic Variations
- Plant Molecular Biology Research
- Plant tissue culture and regeneration
- Plant nutrient uptake and metabolism
- Plant Genetic and Mutation Studies
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- RNA Research and Splicing
- Plant Disease Resistance and Genetics
- Plant Stress Responses and Tolerance
- Genomics and Chromatin Dynamics
- Plant responses to water stress
- Cancer-related molecular mechanisms research
- Plant Reproductive Biology
- Wheat and Barley Genetics and Pathology
- Epigenetics and DNA Methylation
- Genetic Mapping and Diversity in Plants and Animals
- Photosynthetic Processes and Mechanisms
Cold Spring Harbor Laboratory
2011-2024
Howard Hughes Medical Institute
2012-2024
Inari Agriculture (United States)
2023-2024
Bayer (Belgium)
2018
Vrije Universiteit Brussel
2009-2013
Gordon and Betty Moore Foundation
2012
Institute of Plant Genetics, Polish Academy of Sciences
2007
The coordinated expression of highly related homoeologous genes in polyploid species underlies the phenotypes many world's major crops. Here we combine extensive gene datasets to produce a comprehensive, genome-wide analysis homoeolog patterns hexaploid bread wheat. Bias varies between tissues, with ~30% wheat homoeologs showing nonbalanced expression. We found asymmetries along chromosomes, largest inter-tissue, inter-cultivar, and coding sequence variation, most often located...
Genome editing technologies have significantly improved our ability to precisely modify genomes and genes, opening new possibilities engineer endogenous pathways traits. In crops like maize, achieving small indels, base changes structural variation has been demonstrated (Nuccio et al., 2021). However, while these edits typically lead gene knock-out (KO) or knock-down, improvement of many agronomic traits requires higher expression, as evidenced by beneficial natural alleles transgenes. Thus,...
ABSTRACT Drought is one of the most devastating causes yield losses in crops like maize, and anticipated increases severity duration drought spells due to climate change pose an imminent threat agricultural productivity. To understand response, phenotypic molecular studies are typically performed at a given time point after onset, representing steady‐state adaptation response. Because growth dynamic process, we monitored response with high temporal resolution examined cellular transcriptomic...
Epigenetic modifications that arise during plant and animal development, such as DNA histone modification, are mostly reset gamete formation, but some inherited from the germline including those marking imprinted genes
Chromosome dosage plays a significant role in reproductive isolation and speciation both plants animals, but underlying mechanisms are largely obscure 1 . Transposable elements can promote hybridity through maternal small RNA 2 , have been postulated to regulate response via neighboring imprinted genes 3,4 Here, we show that highly conserved microRNA plants, miR845, targets the tRNA Met primer-binding site (PBS) of LTR-retrotransposons Arabidopsis pollen, triggers accumulation 21...