Frédéric Van Ex

ORCID: 0000-0003-2481-0115
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About
Contact & Profiles
Research Areas
  • Chromosomal and Genetic Variations
  • Plant Molecular Biology Research
  • Plant tissue culture and regeneration
  • Plant nutrient uptake and metabolism
  • Plant Genetic and Mutation Studies
  • CRISPR and Genetic Engineering
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Plant Disease Resistance and Genetics
  • Plant Stress Responses and Tolerance
  • Genomics and Chromatin Dynamics
  • Plant responses to water stress
  • Cancer-related molecular mechanisms research
  • Plant Reproductive Biology
  • Wheat and Barley Genetics and Pathology
  • Epigenetics and DNA Methylation
  • Genetic Mapping and Diversity in Plants and Animals
  • Photosynthetic Processes and Mechanisms

Cold Spring Harbor Laboratory
2011-2024

Howard Hughes Medical Institute
2012-2024

Inari Agriculture (United States)
2023-2024

Bayer (Belgium)
2018

Vrije Universiteit Brussel
2009-2013

Gordon and Betty Moore Foundation
2012

Institute of Plant Genetics, Polish Academy of Sciences
2007

R. H. Ramírez-González Philippa Borrill Daniel Lang Sophie A. Harrington Jemima Brinton and 95 more Luca Venturini Mark W. Davey John Jacobs Frédéric Van Ex Asher Pasha Yogendra Khedikar Stephen J. Robinson Aron T. Cory Tobin Florio Lorenzo Concia Caroline Juéry Henk‐jan Schoonbeek Burkhard Steuernagel Daoquan Xiang Christopher J. Ridout Boulos Chalhoub Klaus Mayer Moussa Benhamed David Latrasse Abdelhafid Bendahmane Brande B. H. Wulff R. Appels Vijay Tiwari Raju Datla Frédéric Choulet Curtis Pozniak Nicholas J. Provart Andrew Sharpe Etienne Paux M. Spannagl Andrea Bräutigam Cristóbal Uauy Abraham B. Korol Andrew Sharpe Angéla Juhász Antje Rohde Arnaud Bellec Assaf Distelfeld Bala Anı Akpınar Beat Keller Benoît Darrier Bikram Gill Boulos Chalhoub Burkhard Steuernagel Catherine Feuillet Chanderkant Chaudhary Cristóbal Uauy Curtis Pozniak Danara Ormanbekova Daoquan Xiang David Latrasse David Swarbreck Delfina Barabaschi Dina Raats E. M. Sergeeva Е. А. Салина Etienne Paux Federica Cattonaro Frédéric Choulet Fuminori Kobayashi Gabriel Keeble‐Gagnère Gaganpreet Kaur Gary J. Muehlbauer George Kettleborough Guotai Yu Hana Šimková Heidrun Gundlach Hélène Bergès Hélène Rimbert Hikmet Budak Hirokazu Handa Ian Small Jan Bartoš Jane Rogers Jaroslav Doležel Jens Keilwagen Jesse Poland Joanna Melonek John Jacobs Jon Wright Jonathan D. G. Jones Juan J. Gutiérrez-González Kellye Eversole Kirby T. Nilsen Klaus Mayer K. Kanyuka Kuldeep Singh Liangliang Gao Lorenzo Concia Luca Venturini Luigi Cattivelli M. Spannagl Martin Mascher Matthew Hayden Michaël Abrouk

The coordinated expression of highly related homoeologous genes in polyploid species underlies the phenotypes many world's major crops. Here we combine extensive gene datasets to produce a comprehensive, genome-wide analysis homoeolog patterns hexaploid bread wheat. Bias varies between tissues, with ~30% wheat homoeologs showing nonbalanced expression. We found asymmetries along chromosomes, largest inter-tissue, inter-cultivar, and coding sequence variation, most often located...

10.1126/science.aar6089 article EN Science 2018-08-17

Genome editing technologies have significantly improved our ability to precisely modify genomes and genes, opening new possibilities engineer endogenous pathways traits. In crops like maize, achieving small indels, base changes structural variation has been demonstrated (Nuccio et al., 2021). However, while these edits typically lead gene knock-out (KO) or knock-down, improvement of many agronomic traits requires higher expression, as evidenced by beneficial natural alleles transgenes. Thus,...

10.1111/pbi.14191 article EN cc-by-nc-nd Plant Biotechnology Journal 2023-10-20

ABSTRACT Drought is one of the most devastating causes yield losses in crops like maize, and anticipated increases severity duration drought spells due to climate change pose an imminent threat agricultural productivity. To understand response, phenotypic molecular studies are typically performed at a given time point after onset, representing steady‐state adaptation response. Because growth dynamic process, we monitored response with high temporal resolution examined cellular transcriptomic...

10.1111/pce.15227 article EN Plant Cell & Environment 2024-10-23

Epigenetic modifications that arise during plant and animal development, such as DNA histone modification, are mostly reset gamete formation, but some inherited from the germline including those marking imprinted genes

10.1101/2023.05.27.542553 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-05-30

Chromosome dosage plays a significant role in reproductive isolation and speciation both plants animals, but underlying mechanisms are largely obscure 1 . Transposable elements can promote hybridity through maternal small RNA 2 , have been postulated to regulate response via neighboring imprinted genes 3,4 Here, we show that highly conserved microRNA plants, miR845, targets the tRNA Met primer-binding site (PBS) of LTR-retrotransposons Arabidopsis pollen, triggers accumulation 21...

10.1101/203612 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2017-10-15
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