- Geometric and Algebraic Topology
- Homotopy and Cohomology in Algebraic Topology
- Advanced Combinatorial Mathematics
- Mathematical Dynamics and Fractals
- Computational Geometry and Mesh Generation
- Cytomegalovirus and herpesvirus research
- Hematopoietic Stem Cell Transplantation
- Polyomavirus and related diseases
- Chronic Myeloid Leukemia Treatments
- Lymphoma Diagnosis and Treatment
- semigroups and automata theory
- Geometric Analysis and Curvature Flows
- Chronic Lymphocytic Leukemia Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced Operator Algebra Research
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Advanced Materials and Mechanics
- Connective tissue disorders research
- Finite Group Theory Research
- Potassium and Related Disorders
- Eosinophilic Disorders and Syndromes
- Mathematics and Applications
- Herpesvirus Infections and Treatments
- Advanced Numerical Analysis Techniques
Keio University
2016-2025
Hiroshima University
2015-2024
United Nations University Institute for Sustainability and Peace
2023
Hiroshima University of Economics
2023
Keio University Hospital
2015-2017
Tohoku University
2011-2014
University of Pisa
2014
Hanyang University
2013
Tokyo Institute of Technology
2008
Otsuma Women's University
1996
Phlegmonous gastritis (PG) is a rare, life-threatening bacterial infection characterized by thickening of the gastric wall. We report case PG in 17-year-old male following allogeneic hematopoietic stem cell transplantation for severe aplastic anemia. Seven months after transplantation, patient presented with abdominal pain, fever, and significant wall on CT. Initial antibiotic therapy was initiated immediately. The developed multiple organ failure; however, his condition rapidly improved...
Quantum enhancement polynomials are invariants for oriented links, defined in association with an algebraic structure called a tribracket. In this paper, we focus on the particular case of canonical two-element We prove that, that case, quantum can be recovered by five specific polynomials, which refer to as universal polynomials. After presenting several notable properties these show they strictly stronger than Jones polynomial. Furthermore, provide computational results links up 10 crossings.
Late-onset noninfectious pulmonary complications (LONIPCs), which occur more than 3 months after allogeneic hematopoietic stem cell transplantation (HSCT), are major causes of morbidity and mortality transplantation. Among LONIPCs, we occasionally treat patients with late-onset severe restrictive lung defect HSCT; however, its clinical features have not been fully elucidated.A retrospective chart review a single center on cases HSCT was performed. 453 who survived longer 100 days evaluable...
To evaluate the feasibility of adoptive cell therapy (ACT) using ex vivo-expanded tumor-infiltrating lymphocytes (TILs) in Japanese patients with melanoma who failed immune-checkpoint inhibitor therapy, an open-label, single-arm, pilot study was conducted. We investigated immunological and genetic factors pretreatment tumor expanded TILs that may be associated clinical response. The treatment protocol comprised preparation TIL culture, lympho-depleting non-myeloablative preconditioning...
Cytokine release syndrome (CRS) is the most common adverse event of chimeric antigen receptor T (CAR-T) cell therapy and usually characterized by systemic symptoms such as fever, hypotension, hypoxia. However, there have been several recent reports local CRS cervical swelling. This localized can cause life-threatening laryngeal edema requires early diagnostic treatment. Here we report 3 cases where bilateral salivary gland swelling emerged following anti-CD19 CAR-T for relapsed or refractory...
We provide a classification of the essential surfaces non-negative Euler characteristic in exteriors genus two handlebodies embedded 3-sphere.
BK polyomavirus (BKPyV) is recognized as a pathogen that causes diseases such hemorrhagic cystitis and nephritis after allogeneic hematopoietic stem cell transplantation (HSCT) or renal transplantation. BKPyV-associated disease thought to occur through reactivation under immunosuppression. However, the possibility of its nosocomial transmission clinical significance have not been elucidated. During 6-month period, nine adult patients (median age: 47 years) who had hematological disorders...
Journal Article Connected Primitive Disk Complexes and Genus Two Goeritz Groups of Lens Spaces Get access Sangbum Cho, Cho 1Department Mathematics Education, Hanyang University, Seoul 133-791, Korea Search for other works by this author on: Oxford Academic Google Scholar Yuya Koda 2Department Mathematics, Hiroshima 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan *Correspondence to be sent to: e-mail: ykoda@hiroshima-u.ac.jp International Research Notices, Volume 2016, Issue 23, December...
The genus-g Goeritz group is the of isotopy classes orientationpreserving homeomorphisms a closed orientable 3-manifold that preserve given Heegaard splitting manifold.In this work, we show genus-2 S 2 × 1 finitely presented, and give its explicit presentation.
Abstract We consider the group of isotopy classes automorphisms 3-sphere that preserve a spatial graph or handlebody-knot embedded in it. prove is finitely presented for an arbitrary reducible genus two. also groups “most” irreducible two handlebody-knots are finite.
Given a genus two Heegaard splitting for nonprime 3-manifold, we define special subcomplex of the disk complex one handlebodies splitting, and then show that it is contractible. As applications, first Haken spheres contractible, which refines results Lei Lei-Zhang. Secondly, classify all splittings 3-manifolds, generalization result Montesinos–Safont. Finally, mapping class group called Goeritz group, finitely presented by giving its explicit presentation.
Letermovir has been approved as a novel cytomegalovirus (CMV) prophylactic agent after allogeneic hematopoietic stem cell transplantation (HSCT). However, there are still insufficient data to properly evaluate the real-world role of letermovir, and risk factors for CMV reactivation under letermovir prophylaxis have not clarified.We performed single-institution retrospective analysis patients with or without who underwent HSCT between March 2012 December 2019. In August 2018, was added...
A $3$-manifold which admits a genus-$2$ reducible Heegaard splitting is one of the $3$-sphere, $\mathbb {S}^2 \times \mathbb {S}^1$, lens spaces and their connected sums. For each those manifolds except most spaces, mapping class group was shown to be finitely presented. In this work, we study remaining generic show that presented for any space by giving its explicit presentation. As an application, fundamental groups splittings are all
The first-named author is supported in part by Basic Science Research Program through the National Foundation of Korea funded Ministry Education, and Technology (2012R1A1A1006520). second-named Grant-in-Aid for Young Scientists (B) (no. 20525167), Japan Society Promotion Science.The authors wish to express their gratitude Erica Flapan posing question Darryl McCullough providing his very helpful idea on topic. Part this work was carried out while visiting Mathematisches Forschungsinstitut...