A5100712503- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Cardiac Ischemia and Reperfusion
- Nausea and vomiting management
- Mesenchymal stem cell research
- Opioid Use Disorder Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Tuberculosis Research and Epidemiology
- Anesthesia and Neurotoxicity Research
- Dental Anxiety and Anesthesia Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Infection Control and Ventilation
- Respiratory Support and Mechanisms
- Electrospun Nanofibers in Biomedical Applications
- Discourse Analysis in Language Studies
- Lipoproteins and Cardiovascular Health
- Sports injuries and prevention
- Diabetic Foot Ulcer Assessment and Management
- Spine and Intervertebral Disc Pathology
- Electroconvulsive Therapy Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Nitric Oxide and Endothelin Effects
Massachusetts General Hospital
2015-2025
Harvard University
2015-2025
Shanxi Cardiovascular Hospital
2011-2025
Sichuan Cancer Hospital
2023-2024
Beijing Normal University
2024
Anhui University of Traditional Chinese Medicine
2021-2024
Sun Yat-sen University
2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Zhongshan Hospital
2024
Fudan University
2024
The pathophysiology of pain involves complex nervous system interactions after initial noxious stimuli. When stimuli persist, biochemical and structural changes occur in the nociceptive pathways central peripheral systems, leading to sensitization. Peripheral sensitization are key transition from acute chronic pain. This development is particularly common following various surgical procedures, with many postsurgical patients experiencing persistent for significant periods. Chronic a severe...
Because of cerebrospinal fluid (CSF) leak, orthostatic headaches sometimes follow neuraxial blockade or diagnostic lumbar puncture. Etiology and treatment are straightforward in those settings, since a site dural disruption is known.1,2 With patient consent, we present case which intracranial hypotension resulted from puncture by vertebral osteophytic spur. This scenario illustrates the dilemma spontaneous (SIH), role imaging studies, value empiric epidural blood patch (LEBP).A 36-yr-old...
Sleep is crucial for sustaining normal physiological functions, and sleep deprivation has been associated with increased pain sensitivity. The histone deacetylases (HDACs) are known to significantly regulate in regulating neuropathic pain, but their involvement nociceptive hypersensitivity during still not fully understood. Utilizing a modified multi-platform water environment technique establish model. We measured the expression levels of HDAC1/2 medial prefrontal cortex (mPFC) through...
Esketamine, the S-enantiomer of ketamine, has gained prominence as an adjunct in pain management during general anesthesia due to its higher potency and ability achieve therapeutic effects at lower doses than ketamine. While benefits for relief mental health are well-established, specific esketamine on cardiac function remain under investigation. Anesthesia itself induces physiological changes cardiovascular system, can exacerbate these by increasing sympathetic activity, heart rate, blood...
Sleep is essential for the body's repair and recovery, including supplementation with antioxidants to maintain balance of redox state. Changes in sleep patterns have been reported alter this function, leading changes disease susceptibility or behavior. Here, we recruited healthy male physicians measured extent effect overnight deprivation (SD) recovery (RS) on nociceptive thresholds systemic (plasma-derived) metabolism, namely, major glutathione (GSH), catalase (CAT), malondialdehyde (MDA),...
1. Hyperbaric (HBO(2)) and topical oxygen represent two accepted options to oxygenate tissues. The aim of the present study was investigate effect HBO(2) on energy metabolism anti-oxidant enzymes in a rat model ischaemia-reperfusion (IR) skeletal muscle injury. 2. In first study, 16 rats were randomized HBO(2)-treated group (Group 1; n = 8) an untreated 2; 8). Under general anaesthesia, right hind limb ischaemia produced by application rubber-band tourniquet for 3 h. After 2 h ischaemia,...
Correct species identification is essential before initiation of TB treatment, due to substantial drug susceptibility profile differences among mycobacterial species. Given that nontuberculous mycobacteria (NTM) are frequently resistant first-line anti-tuberculosis drugs, cases with mixed infections Mycobacterium tuberculosis (MTB) and NTM tend be diagnosed as multidrug-resistant (MDR-TB) cases. Here we report results a retrospective multicentre study was conducted determine the prevalence...
Abstract Introduction Upper airway obstruction (UAO) is a major problem in unconscious subjects, making full face mask ventilation difficult. The mechanism of UAO subjects shares many similarities with that obstructive sleep apnea (OSA), especially the hypotonic upper seen during rapid eye movement sleep. Continuous positive pressure (CPAP) via nasal more effective at maintaining patency than patients OSA. We hypothesized CPAP and (nCPAP) would be (FmCPAP) for we tested our hypothesis...
Dyslipidemia International Study II (DYSIS II)-China was conducted to determine the low-density lipoprotein cholesterol (LDL-C) goal (<1.8 mmol/L) attainment rate in patients with post-acute coronary syndrome (ACS).Compliance treatment guideline recommendations improves LDL-C post-ACS patients.This multicenter prospective observational study at 28 tertiary hospitals determined rates admission and 6-month follow-up on lipid-lowering (LLT) for ≥3 months those not LLT (LLT-naive or off months)...