- Phytochemical Studies and Bioactivities
- Natural product bioactivities and synthesis
- Phytochemistry and Bioactive Compounds
- Phytochemistry and Biological Activities
- RNA Interference and Gene Delivery
- Plant-derived Lignans Synthesis and Bioactivity
- Advanced Polymer Synthesis and Characterization
- Heavy metals in environment
- Cholinesterase and Neurodegenerative Diseases
- Phytochemical compounds biological activities
- Tryptophan and brain disorders
- Chemical Synthesis and Analysis
- Heavy Metals in Plants
- Functional Brain Connectivity Studies
- Protein Degradation and Inhibitors
- Drug-Induced Hepatotoxicity and Protection
- Antimicrobial Peptides and Activities
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Photopolymerization techniques and applications
- Biochemical Analysis and Sensing Techniques
- Polydiacetylene-based materials and applications
- Plant Stress Responses and Tolerance
- Medicinal Plant Extracts Effects
- Electrodeposition and Electroless Coatings
- Electron Spin Resonance Studies
Hubei University
2025
Shaanxi University of Chinese Medicine
2018-2024
National Chung Hsing University
2024
Affiliated Hospital of Youjiang Medical University for Nationalities
2021
Central South University
2000-2021
University of Edinburgh
2021
Guangdong Pharmaceutical University
2016-2018
Northwest A&F University
2018
Chengdu University of Traditional Chinese Medicine
2012-2017
Fujian Medical University
2017
Coptis chinensis Franch. is one of the most important medicinal plants globally. However, this species contains relatively high concentrations chromium (Cr) which potentially detrimental to human health. It understand Cr localization and speciation in order evaluate its accumulation transportation mechanisms minimize transfer humans. As little previous work area has been carried out, we utilized synchrotron radiation microscopic X-ray fluorescence (SR-μXRF) laser ablation inductively coupled...
Polygonati rhizoma (PR), a traditional medicinal and edible product with various bioactive components (Polygonatum polysaccharides, saponins, phenols, flavonoids), is widely consumed in China. However, other species morphological characteristics similar to those of the actual are being used replace or adulterate PR, causing issues quality control safety. The similarity PR its substitutes makes classic identification challenging. To address this issue, DNA barcoding-based using ITS2 psbA-trnH...
The mortality rate of ovarian cancer is the highest among gynaecological cancers, primarily due to metastatic symptoms. Recent studies have shown that HOX genes are crucial in tumour progression, but underlying mechanisms remain unclear. Here, HOXC10 expression was examined tissues. function metastasis investigated vitroand via intraperitoneal injection vivo. A total 158 patients with adequate records were enrolled for analysis. associated and poor prognosis cancer. In vitro, overexpression...
B-cell acute lymphocytic leukemia (B-ALL), a common blood cancer in children, leads to high mortality. Cyclin-dependent kinase 9 inhibitor (CDK9i) effectively attenuates myeloid and chronic lymphoblastic by inducing apoptosis inhibiting cell proliferation. However, the effect of CDK9i on B-ALL cells underlying mechanisms remain unclear. In this study, we showed that induced vitro activating apoptotic pathways. addition, restrained glycolytic metabolism cells, CDK9i-induced was enhanced...
Nanofiber scaffolds formed by self-assembling peptide RADA16-I have been used for the study of cell proliferation to mimic an extracellular matrix. In this study, we investigated effect on growth human leukemia cells in vitro and nude mice. Self-assembly assessment showed that molecules excellent ability form stable nanofibers. MTT assay displayed has no cytotoxicity umbilical vein endothelial (HUVECs) vitro. However, inhibited K562 tumors Furthermore, found vascular tube-formation HUVECs...
BACKGROUND:Acute lymphocytic leukemia (ALL) is a common blood cancer which induces high mortality in children. Bromodomains and extra-terminal (BET) protein inhibitors, such as JQ1 ARV-825, are promising therapeutic agents that can be used by targeting c-Myc. A recent work reported effectively attenuates ALL vitro suppressing cell proliferation accelerating apoptosis. The purpose of this research was to probe into the potential mechanism how inhibits vitro. MATERIAL AND METHODS:Cell...
This work introduces a pioneering method using polystyrene spheres to fabricate textured PEDOT:PSS layer, which can notably reduce reflective losses in Sn–Pb PSCs and thus improve the power conversion efficiency.
The use of various binitroxides, with both radical sites similar reactivity, as mediator in the controlled polymerization styrene was examined and rate constants reactions involved were determined at 130 °C. Typical features a observed early stage polymerization, leading to formation two-arm macromolecules containing binitroxide core. At higher conversion, however, continuous decomposition reaction resulted break into dead chain having an unsaturation end group living capped by modified...
Chinese goldthread (Coptis chinensis Franch.) is an important medicinal plant worldwide. However, its clinical safety negatively impacted by high cadmium (Cd) and chromium (Cr) levels. Understanding the accumulation pattern detoxification mechanism of heavy metals, such as Cd Cr, for regulating their transportation reducing in plants. Free amino acids (FAAs), metallothioneins, chemical forms metals are closely associated with metal mechanisms. In present study, we evaluated uptake Cr...
Electroless Ni–P coating was deposited on W–Cu alloy via potential activation at −0·8 V. The characterised for its morphology, structure, microhardness and the corrosion resistance. Scanning electron microscopy observation showed presence of smooth compact crystals in coating. X-ray diffraction analysis that amorphous structure. adhesion between qualified. Heat treatment can improve Both porosity test immersion 10 vol.-% H 2 SO 4 solution revealed exhibited good resistance properties...