A5101756133- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Neonatal Respiratory Health Research
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Thermal Regulation in Medicine
- Muscle and Compartmental Disorders
- Renal and related cancers
- Patient Satisfaction in Healthcare
- Cytokine Signaling Pathways and Interactions
- Nosocomial Infections in ICU
- EEG and Brain-Computer Interfaces
- Simulation-Based Education in Healthcare
- Advanced Sensor and Energy Harvesting Materials
- Morinda citrifolia extract uses
- Paraquat toxicity studies and treatments
- Cardiac Imaging and Diagnostics
- Clinical Reasoning and Diagnostic Skills
- COVID-19 diagnosis using AI
- Dialysis and Renal Disease Management
First Affiliated Hospital of Harbin Medical University
2010-2025
Harbin Medical University
2010-2025
Education Department of Heilongjiang Province
2025
National Health and Family Planning Commission
2022
Second Affiliated Hospital of Harbin Medical University
2020
Fourth Affiliated Hospital of Harbin Medical University
2020
Rhabdomyolysis (RM) frequently gives rise to diverse complications, ultimately leading an unfavorable prognosis for patients. Consequently, there is a pressing need early prediction of survival rates among RM patients, yet reliable and effective predictive models are currently scarce. All data utilized in this study were sourced from the MIMIC-IV database. A multivariable Cox regression analysis was conducted on data, performance new model evaluated based Harrell's concordance index...
Background: This study investigates the clinical features and pulmonary functions of coronavirus disease 2019 (COVID-19) pneumonia survivors at 3 or 6 months after diagnosis in Heilongjiang Province, China. Methods: Forty-six patients with COVID-19 diagnosed starting from February 2020 were enrolled this for follow-up August 2020. These categorized into three groups: Group A ( n = 24) B 11), who moderate severe followed up diagnosis, C diagnosis. Pulmonary functions, arterial blood gas...
Objective: Acute Kidney Injury (AKI) is a renal disease marked by diminished urine output and elevated serum creatinine levels. AKI has global incidence rate of about 20%, with an average mortality 23%. Cardiovascular emerges as one the primary causes death associated AKI. We developed nomogram to estimate probability patients developing congestive heart failure. conducted retrospective study AKI, using MIMIC-III database. The were randomly divided into training validation cohorts. Variables...
Background: Cold exposure has an impact on various respiratory diseases. However, its relationship with idiopathic pulmonary fibrosis (IPF) remains to be elucidated. In this study, bioinformatics methods were utilized explore the potential link between cold and IPF. Methods: exposure-related genes (CERGs) identified using RNA-Seq data from mice exposed versus room temperature conditions, along cross-species orthologous gene conversion. Consensus clustering analysis was performed based CERGs....
Abstract Background Hospital and ICU structural factors are key affecting the quality of care as well patient outcomes. However, data from China scarce. This study was designed to investigate how differences in outcomes associated with hospital structure variables throughout 2019. Methods a multicenter observational study. Data total 2820 hospitals were collected using National Clinical Improvement System that reports information China. collection consisted a) on factors, including type,...
Sepsis is a systemic inflammatory response that can elicit organ dysfunction as well circulatory diseases in serious cases. When responses are especially dysregulated, severe complications arise, including sepsis-induced liver injury. Various microRNAs along with circular (circ) RNAs involved responses; nevertheless, their functions regulating injury remain unknown. The cecal ligation and puncture (CLP) procedure induce polymicrobial sepsis.In this study, CLP was used to sepsis. Then,...
Sepsis is a global public health burden. The sequential organ failure assessment (SOFA) the most commonly used scoring system for diagnosing sepsis and assessing severity. Due to widespread use of endotracheal intubation sedative medications in sepsis, accuracy Glasgow Coma Score (GCS) lowest SOFA. We designed this multicenter, cross-sectional study investigate predictive efficiency SOFA with or without GCS on ICU mortality patients sepsis.
Abstract Objectives: This study investigates the clinical features and pulmonary functions of COVID-19 pneumonia survivors at 3 or 6 months after diagnosis in Heilongjiang Province, China. Methods: Forty-six patients with diagnosed since February 2020 were enrolled this for follow-up July 2020. These categorized into three groups: Group A (n=24) B (n=11) who moderate severe followed up diagnosis; C six diagnosis. Data on function, arterial blood gas analysis, chest CT, test, antibody...
The translocation of intestinal flora has been linked to the colonization diverse and heavy lower respiratory in patients with septic ARDS, is considered a critical prognostic factor for patients.
<title>Abstract</title> <bold>Objective</bold> To evaluate the role of clinical scenario simulation teaching, anchored in a robust case knowledge base, augmenting training critical care medicine specialists. <bold>Methods</bold> A total 60 resident physicians from Department Critical Care Medicine participated this randomized controlled trial July 2021 to December 2022. Participants were randomly assigned either traditional teaching group, which received lectures and standard practice, or...
As a highly contagious disease, coronavirus disease 2019 (COVID-19) is wreaking havoc around the world due to continuous spread among close contacts mainly via droplets, aerosols, contaminated hands or surfaces. Therefore, centralized isolation of and suspected patients an important measure prevent transmission COVID-19. At present, quarantine duration in most countries 14 d fact that incubation period severe acute respiratory syndrome type 2 (SARS-CoV-2) usually identified as 1-14 with...
Liver injury is one of the most common critical clinical illnesses and manifestations multiple organ dysfunction induced by sepsis. The liver plays a central role in development removing bacteria regulating immune inflammation crucial, target sepsis-related injuries. However, mechanism sepsis still not clear. This review discusses pathophysiology, manifestations, treatment injury. injury, pathophysiological mechanism, sepsis,
Objective To explore the effect of lateral and semi-recumbent positions on prognosis stroke patients with pneumonia respiratory failure. Methods A total 68 failure requiring invasive mechanical ventilation were selected from January 2015 to July 2017 in Department Intensive Care Unit First Affiliated Hospital Harbin Medical University, who divided into position group (37 cases) (31 cases). The age, sex ratio, acute physiology chronic health evaluation (APACHE) Ⅱ score, type other...
To investigate the different outcomes of two types acute kidney injury (AKI) according to standard Kidney Disease: Improving Global Outcomes-AKI (KDIGO-AKI), and analyze risk factors that affect prognosis intensive care unit (ICU) patients in China.A secondary analysis was performed on database a previous study conducted by China Critical Care Clinical Trial Group (CCCCTG), which multicenter prospective involving 3 063 22 tertiary ICUs 19 provinces autonomous regions China. The demographic...
Backgound: To investigate the right heart function in COVID-19 (coronavirus disease 2019) patients with acute respiratory distress syndrome (ARDS). Methods: A retrospective analysis of 49 ARDS was performed. Patients were divided into severe and critically group according to severity illness. Age-matched healthy volunteers recruited serving as a control group. The cardiac cavity diameters, tricuspid annular plane systolic excursion (TAPSE), valve regurgitation pressure gradient biggest...
Background: The effects of CD44, via the anti-inflammatory functions autophagy, on lung injuries following pulmonary contusion (PC) and cell apoptosis were investigated. Methods: Acute injury (ALI) mouse models established by inducing PC. This was verified using hematoxylin eosin (H&E) staining, which bronchoalveolar lavage fluid (BALF) collected from these mice for analysis further experimentation. LC3 I/II ratio, Beclin-1, p62 expression levels in A549 cells determined...