A5103231498- Tryptophan and brain disorders
- Bipolar Disorder and Treatment
- Gut microbiota and health
- Animal Genetics and Reproduction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Aquaculture disease management and microbiota
- Diet and metabolism studies
- Chromosomal and Genetic Variations
- Genetic diversity and population structure
- Reproductive biology and impacts on aquatic species
- Functional Brain Connectivity Studies
- Genomics and Phylogenetic Studies
- Video Surveillance and Tracking Methods
- Epigenetics and DNA Methylation
- Inflammasome and immune disorders
- Heart Rate Variability and Autonomic Control
- Identification and Quantification in Food
- Genetic Associations and Epidemiology
- Adolescent and Pediatric Healthcare
- Neuroinflammation and Neurodegeneration Mechanisms
- Mental Health Research Topics
- Digital Media Forensic Detection
- Shape Memory Alloy Transformations
- Heat shock proteins research
- Gastrointestinal motility and disorders
Jiangnan University
2024-2025
Old Dominion University
2018-2024
Zhejiang Chinese Medical University
2023-2024
First Affiliated Hospital of GuangXi Medical University
2024
Guangxi Medical University
2024
Nantong University
2024
First Affiliated Hospital Zhejiang University
2020-2023
Nanjing Normal University
2022
Zhejiang Sci-Tech University
2022
Zero to Three
2021
Gut microbiome disturbances have been implicated in major depressive disorder (MDD). However, little is known about how the gut virome, microbiome, and fecal metabolome change, they interact MDD. Here, using whole-genome shotgun metagenomic untargeted metabolomic methods, we identified 3 bacteriophages, 47 bacterial species, 50 metabolites showing notable differences abundance between MDD patients healthy controls (HCs). Patients with were mainly characterized by increased of genus...
Most of the previous studies have demonstrated potential antidepressive and anxiolytic role prebiotic supplement in male subjects, yet few females enrolled. Herein, we explored whether prebiotics administration during chronic stress prevented depression-like anxiety-like behavior a sex-specific manner mechanism behavioral differences caused by sex.
The mechanism of bipolar disorder is unclear. Growing evidence indicates that gut microbiota plays a pivotal role in mental disorders. This study aimed to find out changes the depression (BD) subjects following treatment with quetiapine, and evaluate their correlations brain immune function. Totally 36 BD 27 healthy controls (HCs) were recruited. severity was evaluated Montgomery–Asberg Depression Rating Scale (MADRS). At baseline, fecal samples collected analyzed by quantitative polymerase...
Preclinical studies have shown that the gut microbiota can play a role in schizophrenia (SCH) pathogenesis via gut-brain axis. However, its antipsychotic treatment response is unclear. Here, we present 24-week follow-up study to identify microbial biomarkers for SCH diagnosis and response, using sample of 107 first-episode, drug-naïve patients, healthy controls (HCs). We collected biological samples at baseline (all participants) time points after risperidone (SCH patients). Treatment was...
Abstract Background Preliminary studies have indicated metabolic dysfunction and gut dysbiosis in patients with bipolar disorder (BD). In this study, we aimed to clarify the impact of microbial composition function on BD an acute depressive episode. Methods Fresh fecal samples were provided from 58 depression, including 29 normal weight (NW) overweight/obesity (OW), 31 healthy controls (HCs). The hypervariable region 16 S rRNA gene (V3‐V4) sequencing was performed using IonS5TMXL platform...
Virtual reality based physical stress (VRPS) paradigms could eliminate the influence of social factors on participants, and it may be a desirable tool to explore impact personality traits levels. In this study, we attempt effects VRPS response among individuals with different traits. Forty male participants an average age 22.79 ± 0.41 years were divided into two groups Harm Avoidance (HA) scores Tridimensional Personality Questionnaire (TPQ), referred as Low-HA group High-HA group. The...
Abstract Trillions of microorganisms inhabiting in the human gut play an essential role maintaining physical and mental health. The connections between microbiome neuropsychiatric diseases have been recently identified. pathogenesis bipolar disorder, a spectrum manifesting with mood energy fluctuations, also seems to be involved bidirectional modulation microbiome‐gut‐brain (MGB) axis. In this review, we briefly introduce concept MGB axis, then focus on previous findings studies associated...
Innate immunity is the first and essential line for resisting pathogens, immune intensity duration need to be strictly regulated balance excessive or insufficient response. MicroRNAs (miRNAs) are crucial regulators of response in Drosophila, yet how immune-related miRNAs remains poorly understood. Herein, we elucidated that involvement miR-317 NF-κB transcription factor Relish mediated Drosophila Imd pathway Gram-negative (G-) bacteria stimulation. Remarkably, dynamic expression profiling...
Tetratricopeptide repeat and ankyrin containing 1 (TRANK1) is a robust risk gene of bipolar disorder (BD). However, little known on the role TRANK1 in pathogenesis BD whether gut microbiota capable regulating expression. In this study, we first investigated serum mRNA level medication-free patients with depressive episode BD, then mice model was constructed by fecal transplantation (FMT) to explore effects brain expression neuroinflammation, which further verified vitro Lipopolysaccharide...
Background: Looking pattern differences are shown to separate individuals with Autism Spectrum Disorder (ASD) and Typically Developing (TD) controls. Recent studies have that, in children ASD, these patterns change intellectual social impairments, suggesting that of attention provide indices clinically meaningful variation ASD. Method: We conducted a naturalistic study ASD (n = 55) typical development (TD, n 32). A battery eye-tracking video stimuli was used the study, including Activity...