A5054449087- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Lanthanide and Transition Metal Complexes
- Transcranial Magnetic Stimulation Studies
- Atomic and Subatomic Physics Research
- Cardiac Imaging and Diagnostics
- Ultrasound and Hyperthermia Applications
- Electron Spin Resonance Studies
- Photoacoustic and Ultrasonic Imaging
- EEG and Brain-Computer Interfaces
- Medical Imaging Techniques and Applications
- Neural and Behavioral Psychology Studies
- Cerebrovascular and Carotid Artery Diseases
- Sparse and Compressive Sensing Techniques
- Ultrasound Imaging and Elastography
- Cardiovascular Health and Disease Prevention
- Neurological disorders and treatments
- Tensor decomposition and applications
- Mental Health Research Topics
- Muscle activation and electromyography studies
- Pain Mechanisms and Treatments
- Olfactory and Sensory Function Studies
- Cardiovascular Function and Risk Factors
University of Michigan–Ann Arbor
2015-2024
Michigan United
2021
University of Iceland
2014
Magnetic Resonance Innovations (United States)
2007
Abstract Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic processes involved in various neurological disorders and guiding clinical decision‐making. This guidelines article provides a comprehensive overview quantitative imaging brain using multi‐timepoint arterial spin labeling (ASL), along with recommendations its acquisition quantification. A major benefit acquiring ASL data multiple label durations and/or post‐labeling delays (PLDs) being able to...
Some individuals have very specific and differentiated emotional experiences, such as anger, shame, excitement, happiness, whereas others more general affective experiences of pleasure or discomfort that are not highly differentiated. Considering with major depressive disorder (MDD) cognitive deficits for negative information, we predicted people MDD would less than healthy people. To test this hypothesis, assessed participants’ using a 7-day experience-sampling protocol. Depression was...
This review provides a summary statement of recommended implementations arterial spin labeling (ASL) for clinical applications. It is consensus the ISMRM Perfusion Study Group and European ASL in Dementia consortium, both whom met to reach this October 2012 Amsterdam. Although continues undergo rapid technical development, we believe that current methods are robust ready provide useful information, on will help community adopt standardized approach. In review, describe major considerations...
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows for quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting acquisition parameters complicates quantification, analysis, and sharing ASL data, particularly studies across multiple sites, platforms, methods. There strong need standardization data storage, including metadata. Recently, ASL-BIDS, the BIDS extension ASL, was developed released in 1.5.0. This manuscript provides an overview...
Pseudo‐continuous arterial spin labeling (pCASL) is a very powerful technique to measure cerebral perfusion, which circumvents the problems affecting other continuous schemes, such as magnetization transfer and duty cycle. However, some variability in tagging efficiency of pCASL has been reported. This article investigates effect B 0 field inhomogeneity on pulse sequence possible cause this variability. Both theory simulated data predict that pseudo‐continuous pulses can be degraded presence...
Transcranial magnetic stimulation (TMS) is a tool for noninvasive of neuronal tissue used research in cognitive neuroscience and to treat neurological disorders. Many TMS applications call large electric fields be sharply focused on regions that often lie deep inside the brain. Unfortunately, generated by present-day coils diffuse decay rapidly as they penetrate into head. As result, tend stimulate relatively near brain surface. Earlier studies suggested excitation can attained using...
Functional MRI using blood-oxygen-level-dependent (BOLD) imaging has provided unprecedented insights into the maturation of human brain. Task-based fMRI studies have shown BOLD signal increases with age during development (ages 5-18) for many cognitive domains such as language and executive function, while functional connectivity (resting-state) investigating regionally synchronous fluctuations revealed a developing organization brain from local more distributed architecture. However,...
A computational framework for uncertainty quantification in transcranial magnetic stimulation (TMS) is presented. The leverages high-dimensional model representations (HDMRs), which approximate observables (i.e., quantities of interest such as electric (E) fields induced inside targeted cortical regions) via series iteratively constructed component functions involving only the most significant random variables parameters that characterize a TMS setup position and orientation coils, well...
Purpose To compare a double-excitation combined arterial-spin labeling/blood-oxygenation level dependent (ASL/BOLD) functional imaging method to double-echo method. ASL provides useful complement standard BOLD imaging, map effects of cerebral hemodynamics. Whole-brain is necessary properly characterize large networks. A challenge whole-brain ASL/BOLD that images for contrast must be acquired before significant longitudinal relaxation the inverted spins occurs; however, longer echo time (TE)...
The present study tested the hypothesis that network segregation, a graph theoretic measure of functional organization brain, is correlated with treatment response in patients major depressive disorder (MDD) undergoing repetitive transcranial magnetic stimulation (rTMS). Network calculated from resting state resonance imaging scans, was measured 32 MDD who entered sham-controlled, double-blinded, randomized trial rTMS to left dorsolateral prefrontal cortex, and cohort 20 healthy controls...
Abstract Arterial spin labeling (ASL) provides quantitative and reproducible measurements of regional cerebral blood flow, is therefore an attractive method for functional MRI. However, most existing ASL MRI protocols are based on either two‐dimensional (2D) multislice or 3D spin‐echo suffer from very low image signal‐to‐noise ratio through‐plane blurring. with multishot (segmented) readouts can improve the efficiency relative to 2D does not T 2 ‐blurring. segmented require lower imaging...
Noxious cutaneous contact heat stimuli (48 °C) are perceived as increasingly painful when the stimulus duration is extended from 5 to 10 s, reflecting temporal summation of central neuronal activity mediating pain. However, sensation increasing pain disappears, reaching a plateau increases 20 s. We used functional magnetic resonance imaging (fMRI) in healthy subjects determine if active mechanisms could contribute this psychophysical plateau. During durations ranging activation intensities...
Purpose To develop MRI feedback for cavitation‐based, focused ultrasound, tissue erosion surgery (histotripsy), we investigate image contrast generated by transient cavitation events. Methods Changes in GRE intensity are observed while balanced pairs of field gradients varied the presence an acoustically driven event. The amplitude acoustic pulse and timing between a event start these gradient waveforms also varied. magnitudes phases site compared with those control images. An echo‐planar...