A5055818158- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Optical Imaging and Spectroscopy Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Lanthanide and Transition Metal Complexes
- Cerebrovascular and Carotid Artery Diseases
- Ethics in Clinical Research
- Traumatic Brain Injury Research
- Atomic and Subatomic Physics Research
- Health, Environment, Cognitive Aging
- Patient Dignity and Privacy
- Cerebrospinal fluid and hydrocephalus
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Brain Tumor Detection and Classification
- Biological Research and Disease Studies
- Advanced Electron Microscopy Techniques and Applications
- Brain Metastases and Treatment
- Cancer-related cognitive impairment studies
- Management and Organizational Studies
Ghent University
2018-2024
Ghent University Hospital
2017-2024
Brighton and Sussex Medical School
2020
Arterial spin labeling (ASL) has undergone significant development since its inception, with a focus on improving standardization and reproducibility of acquisition quantification. In community-wide effort towards robust reproducible clinical ASL image processing, we developed the software package ExploreASL, allowing standardized analyses across centers scanners. The procedures used in ExploreASL capitalize published processing advancements address challenges multi-center datasets...
Arterial spin labeling (ASL) is a non-invasive MRI technique that allows for quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting acquisition parameters complicates quantification, analysis, and sharing ASL data, particularly studies across multiple sites, platforms, methods. There strong need standardization data storage, including metadata. Recently, ASL-BIDS, the BIDS extension ASL, was developed released in 1.5.0. This manuscript provides an overview...
Introduction Loss of blood-brain barrier (BBB) integrity is hypothesised to be one the earliest microvascular signs Alzheimer’s disease (AD). Existing BBB imaging methods involve contrast agents or ionising radiation, and pose limitations in terms cost logistics. Arterial spin labelling (ASL) perfusion MRI has been recently adapted map permeability non-invasively. The DEveloping BBB-ASL as a non-Invasive Early biomarker (DEBBIE) consortium aims develop this modified ASL-MRI technique for...
Abstract The 2015 consensus statement published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group and European Cooperation Science Technology ( COST) Action ASL Dementia aimed to encourage implementation of robust arterial spin labeling (ASL) perfusion MRI clinical applications promote consistency across scanner types, sites, studies. Subsequently, recommended 3D pseudo‐continuous sequence has been implemented most major manufacturers. However,...
Having the means to share research data openly is essential modern science. For human research, a key aspect in this endeavour obtaining consent from participants, not just take part study, which basic ethical principle, but also their with scientific community. To ensure that participants’ privacy respected, national and/or supranational regulations and laws are place. It is, however, always clear researchers what implications of those are, nor how comply them. The Open Brain Consent...
Purpose To determine whether sacrificing part of the scan time pseudo‐continuous arterial spin labeling (PCASL) for measurement efficiency and blood is beneficial in terms CBF quantification reliability. Methods In a simulation framework, 5‐minute protocols with different divisions between PCASL data acquisition supporting measurements were evaluated estimation variability across both noise ground truth parameter realizations taken from general population distribution. The entire experiment...
Multi‐post‐labeling‐delay pseudo‐continuous arterial spin labeling (multi‐PLD PCASL) allows for absolute quantification of the cerebral blood flow (CBF) as well transit time (ATT). Estimating these perfusion parameters from multi‐PLD PCASL data is a non‐linear inverse problem, which commonly tackled by fitting single‐compartment model (SCM) PCASL, with CBF and ATT free parameters. The longitudinal relaxation tissue T 1 t an important parameter in this model, it governs decay signal entirely...
Arterial spin labeling (ASL) is a non-invasive MRI technique, allowing quantitative measurement of cerebral perfusion. Incomplete or inaccurate reporting acquisition parameters complicates quantification, analysis, and sharing ASL data, particularly for studies across multiple sites, platforms, methods. Therefore, there strong need standardization data storage, including metadata. Recently ASL-BIDS, the BIDS extension ASL, was developed released in 1.5.0. This manuscript provides an overview...
Abstract Arterial spin labeling (ASL) has undergone significant development since its inception, with a focus on improving standardization and reproducibility of acquisition quantification. In community-wide effort towards robust reproducible clinical ASL image processing, we developed the software package ExploreASL, allowing standardized analyses across centers scanners. The procedures used in ExploreASL capitalize published processing advancements address challenges multi-center datasets...
Event Abstract Back to Review of confounding effects on perfusion measurements Patricia Clement1*, Henk-Jan Mutsaerts2, Eidrees Ghariq2, Marion Smits3, Marjan Acou1, Egill Rostrup4, Francesca Benedetta Pizzini5, Jorge Jovicich6, Mervi Könönen7, Ritva Vanninen7, António Bastos-Leite8, Roland Wiest9, Elna-Marie Larsson10 and Eric Achten1 1 Ghent University, Belgium 2 Leiden University Medical Center, Netherlands 3 Erasmus MC, 4 Copenhagen, Denmark 5 Hospital Verona, Italy 6 Trento, 7 Kuopio...
Abstract This guide summarizes the state-of-the-art processing software solutions and repositories/communities for following advanced MRI methods: DSC; DCE; ASL; diffusion MRI; relaxometry; MRF; MRS; CEST; SWI; QSM; MRE; task-based resting-state fMRI. For each of those, after a short introduction about method output parameters, required recommended image steps quality control measures are described, we point to further literature more details. In addition, an overview openly available tools...
BackgroundTo date, multiple advanced magnetic resonance imaging (MRI) methods beyond conventional qualitative structural for the diagnosis, prognosis, and treatment follow-up of glioma have demonstrated their utility clinical studies. However, these often rely on complex off-scanner processing to yield most information extract quantitative biomarkers, limiting practical use studies, as well translation.While community-driven software solutions exist MRI methods, many aspiring researchers...
To overcome long acquisition times of Chemical Shift Imaging (CSI), a new Magnetic Resonance Spectroscopic (MRSI) technique called Reduction Acquisition time by Partition the sIgnal Decay in (RAPID-SI) using blipped phase encoding gradients inserted during signal was developed. validate results RAPID-SI and to demonstrate its usefulness terms data quantification; simulations, phantom vivo studies were conducted, compared standard CSI. The method based upon partition magnetic resonance...