A5064039593- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Lanthanide and Transition Metal Complexes
- Bone and Joint Diseases
- Intracranial Aneurysms: Treatment and Complications
- Functional Brain Connectivity Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Development and Preterm Care
- Child and Adolescent Psychosocial and Emotional Development
- Fetal and Pediatric Neurological Disorders
- Thermal Regulation in Medicine
- Vascular Malformations Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Cervical and Thoracic Myelopathy
- Cerebrospinal fluid and hydrocephalus
- Radiomics and Machine Learning in Medical Imaging
- Sepsis Diagnosis and Treatment
- Phytochemistry and Biological Activities
- Virology and Viral Diseases
- Moyamoya disease diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Pulmonary Hypertension Research and Treatments
Wellcome Centre for Integrative Neuroimaging
2019-2025
University of Oxford
2018-2025
University of Tsukuba
2023
Hokkaido University
2006-2023
Senshu University
2023
University of Toyama
2023
Leiden University Medical Center
2017-2021
Hamamatsu University School of Medicine
2021
Hamamatsu University
2019
Institute of Biomedical Science
2019
Amide proton transfer (APT) imaging is a novel molecular MRI technique to detect endogenous mobile proteins and peptides through chemical exchange saturation transfer. We prospectively assessed the usefulness of APT in predicting histological grade adult diffuse gliomas.Thirty-six consecutive patients with histopathologically proven glioma (48.1 ± 14.7 y old, 16 males 20 females) were included study. was conducted on 3T clinical scanner obtained 2 s at 25 frequency offsets ω = -6 +6 ppm...
Abstract Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic processes involved in various neurological disorders and guiding clinical decision‐making. This guidelines article provides a comprehensive overview quantitative imaging brain using multi‐timepoint arterial spin labeling (ASL), along with recommendations its acquisition quantification. A major benefit acquiring ASL data multiple label durations and/or post‐labeling delays (PLDs) being able to...
To investigate the use of root mean square displacement (RMSD) and diffusional kurtosis (DK) metrics q-space imaging data to estimate spinal cord compression in patients with early cervical spondylosis.We studied 50 consecutive at our institution (22 male, 28 female; age 58 years; range 20-86 years) who had clinical signs symptoms suggestive stage myelopathy. After conventional magnetic resonance (MR) imaging, diffusion tensor image were acquired using 3-T MR imaging. Fractional anisotropy...
Abstract The Human Connectome Project Lifespan studies cover the development (5–21) and ageing (36–100+) phases of life. Arterial spin labelling (ASL) was included in imaging protocol, resulting one largest datasets collected to date high spatial resolution multiple delay ASL covering 3,000 subjects. human connectome project (HCP)-ASL minimal processing pipeline developed specifically for this dataset pre-process image data produce perfusion estimates both volumetric surface template space,...
We investigated microstructural changes in the spinal cord, separately for white matter and gray matter, patients with cervical spondylosis by using diffusional kurtosis imaging (DKI). studied 13 consecutive myelopathy (15 affected sides 11 unaffected sides). After conventional magnetic resonance (MR) imaging, DKI data were acquired a 3 T MR scanner. Values fractional anisotropy (FA), apparent diffusion coefficient (ADC), mean (MK) calculated compared between cords, matter. Tract-specific...
Purpose To evaluate the reproducibility of amide proton transfer (APT) imaging brain tumors using a parallel transmission‐based technique. Materials and Methods Thirteen patients with (four low‐grade gliomas, three glioblastoma multiforme, five meningiomas, one malignant lymphoma) were included in study. APT was conducted at 3T 2‐channel transmission scheme saturation time 2 seconds B 1 amplitude μT. A 2D fast spin‐echo sequence driven‐equilibrium refocusing used for imaging. Z‐spectra...
Abstract The 2015 consensus statement published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group and European Cooperation Science Technology ( COST) Action ASL Dementia aimed to encourage implementation of robust arterial spin labeling (ASL) perfusion MRI clinical applications promote consistency across scanner types, sites, studies. Subsequently, recommended 3D pseudo‐continuous sequence has been implemented most major manufacturers. However,...
Objective: To determine whether positron emission tomography (PET) with tracer 18-fluorodeoxyglucose (FDG-PET) yields additional information in the diagnosis of malignancy compared magnetic resonance imaging (MRI) findings selected women after screening for ovarian masses by ultrasonography (US). Methods: After 49 patients were screened US and physical examination (including a pelvic examination) 2 experienced gynecologic oncologists, 38 suspected having cancer enrolled study. All underwent...
<h3>BACKGROUND AND PURPOSE:</h3> Intra-arterial DSA has been traditionally used for confirmation of cure following gamma knife radiosurgery AVMs. Our aim was to evaluate whether 4D arterial spin-labeling MRA and contrast-enhanced time-resolved in combination can be an alternative AVM obliteration radiosurgery. <h3>MATERIALS METHODS:</h3> In this prospective study, 30 patients undergoing AVMs (criterion standard) also underwent MRA, including MRA. One dataset technically unsatisfactory, the...
A 38-year-old multiparous woman was referred at 19 weeks' gestation because of hydrops fetalis. Ultrasonic examination revealed severe pleural effusion, ascites and skin edema. Detailed the amniotic fluid, fetal blood intrathoracic fluid led to a diagnosis congenital chylothorax. Repeated thoracocenteses were not effective in improving We introduced treatment for effusion by an intrapleural injection OK-432 23, 24 25 gestation. The reduced adhesion space resulted delivery neonate who healthy...
We investigated changes in the optic tract and radiation patients with multiple sclerosis (MS) by comparing unilateral bilateral nerve damage assessed based on visual evoked potentials (VEPs) using advanced diffusion MR metrics. In 21 MS patients, MRI was performed. Maps of fractional anisotropy, apparent coefficient (ADC), mean kurtosis (MK) were computed. On basis P100 latency VEPs, divided into three groups: (n = 7), no abnormality 7). Their tracts radiations analyzed MRI-based fiber...
We evaluated the brain lesions of patients with chronic alcoholism (n = 34) in comparison age- and sex-matched controls 40) by MR imaging. T1-weighted sagittal axial images T2-weighted were obtained a 0.5 T superconducting unit. Various measurements then performed, presence regions abnormal signal intensity was also compared between two groups. The revealed significant cerebral atrophy (characterized lateral 3rd ventricular dilatation, widening interhemispheric fissure) as well cerebellar...