A5104273556- Automotive and Human Injury Biomechanics
- Traumatic Brain Injury Research
- Injury Epidemiology and Prevention
- Medical Imaging and Analysis
- Sports injuries and prevention
- Spine and Intervertebral Disc Pathology
- Traffic and Road Safety
- Advanced Neuroimaging Techniques and Applications
- Occupational Health and Performance
- Pelvic and Acetabular Injuries
- Trauma Management and Diagnosis
- Prosthetics and Rehabilitation Robotics
- Elasticity and Material Modeling
- Muscle activation and electromyography studies
- Colorectal Cancer Screening and Detection
- Advanced MRI Techniques and Applications
- Colorectal Cancer Surgical Treatments
- Musculoskeletal pain and rehabilitation
- Colorectal and Anal Carcinomas
- Agriculture and Farm Safety
- Functional Brain Connectivity Studies
- Neuroscience and Neural Engineering
- Spinal Fractures and Fixation Techniques
- Trauma and Emergency Care Studies
- Spaceflight effects on biology
Winston-Salem/Forsyth County Schools
2021-2024
Hospital Alemão Oswaldo Cruz
2024
Beneficência Portuguesa de São Paulo
2024
Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences
2015-2022
University Hospital of Wales
2022
John Wiley & Sons (United States)
2022
Erasmus MC Cancer Institute
2021
Leiden University
2021
Centre for Biomedical Engineering and Physics
2021
Wake Forest University
2015-2020
Physical differences between youth and adults, which include incomplete myelination, limited neck muscle development, a higher head-body ratio in the population, likely contribute towards increased susceptibility of to concussion. Previous research efforts have considered biomechanics concussion for adult populations, but these known age-related highlight necessity quantifying risk population. This study adapted previously developed Generalized Acceleration Model Brian Injury Threshold...
PURPOSE Organ preservation has become an attractive alternative to surgery (total mesorectal excision [TME]) among patients with rectal cancer after neoadjuvant therapy who achieve a clinical complete response (cCR). Nearly 30% of these will develop local regrowth (LR). Although salvage resection is frequently feasible, there may be increased risk for development subsequent distant metastases (DM). The aim this study compare the DM between LR Watch and Wait (WW) near-complete pathologic...
Approximately 5,000,000 athletes play organized football in the United States, and youth constitute largest proportion with ∼3,500,000 participants. Investigations of head impact exposure (HIE) have been limited size duration. The objective this study was to evaluate HIE participating three age- weight-based levels within a single organization over four seasons. Head data were collected using Impact Telemetry (HIT) System. Mixed effects linear models fitted, Wald tests used assess...
The aging population is a growing concern as the increased fragility and frailty of elderly results in an elevated incidence injury well risk mortality morbidity. To assess risk, age-specific computational models can be developed to directly calculate biomechanical metrics for injury. first objective was develop older occupant Global Human Body Models Consortium (GHBMC) average male model (M50) representative 65 year old (YO) perform regional validation tests investigate predicted fractures...
Young-onset rectal cancer, in patients less than 50 years, is expected to increase the coming years. A watch-and-wait strategy nowadays increasingly practised with a clinical complete response (cCR) after neoadjuvant treatment. Nevertheless, there may be reluctance offer organ preservation treatment young owing potentially higher oncological risk. This study compared aged years those or more identify possible differences outcomes of watch and wait.The analysed data from cCR therapy whom...
Incisional hernias cause morbidity and may require further surgery. HART (Hughes Abdominal Repair Trial) assessed the effect of an alternative suture method on incidence incisional hernia following colorectal cancer
The objective of this study was to reconstruct 4 real-world motor vehicle crashes (MVCs), 2 with lumbar vertebral fractures and without in order elucidate the MVC and/or restraint variables that increase injury risk.A finite element (FE) simplified model (SVM) used conjunction a previously developed semi-automated tuning method arrive at SVMs were tuned mimic frontal crash responses 2006 Chevrolet Cobalt, 2012 Ford Escape, 2007 Hummer H3, 2002 Cavalier. Real-world first vehicles resulted...
Cartilaginous tumours of the larynx are rare. Chondrosarcomas represent most common sarcoma involving this site. A series seven patients with diagnosis chondrosarcoma from cancer registry at University Michigan Medical Center 1975 to 1997 and one recent case Ann Arbor Department Veterans Affairs Hospital were identified. One patient a laryngeal chondroma was also included in series. Pertinent clinical, pathologic, therapeutic data reviewed. In three nine patients, involved thyroid cartilage;...
This study aimed to compare head impact exposures between practices and games in football players ages 9 14 years, who account for approximately 70% of all the United States. Over a period 2 seasons, 136 were enrolled from 3 youth programs, 49,847 impacts recorded 345 137 games. During study, individual sustained median 211 per season, with maximum 1226 impacts. Players 50th (95th) percentile peak linear acceleration 18.3 (46.9) g, rotational 1305.4 (3316.6) rad·s
Abstract Objectives: Head impact exposure (HIE) in youth football is a public health concern. The objective of this study was to determine if one season HIE related cognitive changes. Method: Over 200 participants (ages 9–13) wore instrumented helmets for practices and games measure the amount sustained over season. Pre- post-season neuropsychological tests were completed. Test score changes calculated adjusting practice effects regression mean used as dependent variables. Regression models...
Prosthetic electrical stimulation of the auditory system is presently accomplished either via scala tympani electrode arrays or cochlear nucleus surface arrays. Many early implant studies, however, used placed within nerve itself--either modiolus trunk nerve. For many reasons, such intraneural were abandoned in favor intrascalar There remain, several theoretical and practical reasons why might be advantageous, recent developments technology solve problems posed by attempts at stimulation. In...
Objective: A recent emphasis on nontraditional seating and omnidirectional impact directions has motivated the need for deformable representation of thoracic spine (T-spine) in human body models. The goal this study was to develop validate a T-spine Global Human Body Models Consortium (GHBMC) M50-O (average male occupant) model demonstrate improved biofidelity.Methods: Eleven functional spinal units (FSUs) were developed with vertebrae (cortical trabecular), costovertebral ligaments,...
ABSTRACT Purpose Head impact exposure (HIE) (i.e., magnitude and frequency of impacts) can vary considerably among individuals within a single football team. To better understand individual-specific factors that may explain variation in head biomechanics, this study aimed to evaluate the relationship between physical performance measures HIE metrics youth players. Methods data were collected from players using Impact Telemetry System. was quantified terms frequency, linear rotational...
To reduce head impact exposure (HIE) in youth football, further understanding of the context which impacts occur and associated biomechanics is needed. The objective this study was to evaluate effect contact characteristics on HIE during player versus scenarios football. Head data time-synchronized video were collected from 4 football games over 2 seasons opposing teams instrumented with Impact Telemetry (HIT) System. Coded included player's role contact, speed body position, height, type,...
Objective: Lower extremity injuries are the most frequent Abbreviated Injury Scale (AIS) 2 injury for drivers in frontal crashes. The objective was to reconstruct 11 real-world motor vehicle crashes (2 with AIS 2+ distal lower and 9 without injury) analyze parameters driver attributes that affect risk.Methods: Eleven were reconstructed a finite element simplified model (SVM) using semi-automated optimization method. SVM tuned each corresponding Total HUman Model Safety (THUMS) Ver 4.01...