- Tracheal and airway disorders
- Cancer Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Spinal Fractures and Fixation Techniques
- MRI in cancer diagnosis
- Esophageal and GI Pathology
- Angiogenesis and VEGF in Cancer
- Medical Imaging Techniques and Applications
- Airway Management and Intubation Techniques
- Multiple and Secondary Primary Cancers
- Neurofibromatosis and Schwannoma Cases
- Pulmonary Hypertension Research and Treatments
- Pelvic and Acetabular Injuries
- Teratomas and Epidermoid Cysts
- Management of metastatic bone disease
- Phytochemistry and biological activity of medicinal plants
- Breast Lesions and Carcinomas
- Caveolin-1 and cellular processes
- Pregnancy-related medical research
- Cutaneous lymphoproliferative disorders research
- Cancer and Skin Lesions
- Foreign Body Medical Cases
Kanazawa University
2025
Japanese Red Cross Narita Hospital
2024
Asahi General Hospital
1993-2019
Daiichi Sankyo (Germany)
2017
Daiichi-Sankyo (Japan)
2017
Génétique Médicale & Génomique Fonctionelle
2016
Keio University
2014
Kawasaki Municipal Hospital
2014
Kyoto University Hospital
2004
Nagano Prefectural Suzaka Hospital
2004
Chemotherapy resistance remains a major obstacle for eradicating metastatic cancer cells in distant organs. We identified that endothelial (ECs) the lungs, where breast often metastasize, form chemoresistant perivascular niche disseminated cells. By investigating lung EC secretome activated by metastasis, we found serine protease inhibitor family E member 1 (SERPINE1), encoded Serpine1, is upregulated metastasis-associated ECs. This upregulation shields from paclitaxel-induced apoptosis and...
Sacral insufficiency fractures (SIFs) are common in the elderly. In patients with SIF, objective neurological abnormalities such as sphincter dysfunction or leg paresthesia uncommon. We present a case of SIF accompanied by spinopelvic dissociation late compromise treated fixation. A 61-year-old woman presented to our hospital low back pain without obvious trauma history. She had past history eosinophilic granulomatosis polyangiitis and treatment steroids. Her became worse, she started have...
An occipital condyle fracture (OCF) is a relatively rare trauma that now increasingly diagnosed because of the wide availability computed tomography. For nondisplaced OCFs, conservative treatment generally recommended, and there no previous report OCF requiring surgery. We patient who had with craniocervical misalignment (a condyle-C1 interval > 2.0 mm) C1-C2 translation treated halo vest occipitocervical fusion 87-year-old Asian woman fell from 4-meter height hit her head. She was...
BACKGROUND: Malignant pediatric brain tumors constitute a heterogeneic group of central nervous system tumors, and general markers diagnosis prognosis are not available. Recently, panel CD (CD15, CD24, CD29) was used to define increasing neural differentiation embryonic stem cells. Although these have been associated with worse due presence tumor propagating cells, alterations in adhesion migration various cancer types, no studies multiple performed. METHODS: We collected including...
6072 Background: Since 1980s, 18FDG-PET imaging has been used as a modality to improve cancer patient management. Although scan is potentially useful in early detection of disease recurrence after primary treatment patients, its effectiveness screening still unclear. Nevertheless, Japan, very recently, asymptomatic individuals consult PET clinics for screening. The total annual number them exceeded 5000 at the Nishidai clinic, Tokyo, Japan. Methods: From Aug 1, 2002 Jul 31, 2003, 5816...
副乳癌の1例を経験したので若干の文献的考察を加えて報告する.【症例】88歳,女性.平成14年3月,右腋窩の腫瘤性病変を自覚し当科受診.右腋窩に直径2cm大の腫瘤を認め, 3/25局所麻酔下に生検施行.術後の病理学的検索にて副乳癌の診断を得た. 4/19全身麻酔下に遺残腫瘤切除・腋窩リンパ節郭清(level I)を施行.切除標本に明らかな癌の遺残,腋窩リンパ節転移を認めなかった.現在外来にてAnastrozole内服下に経過観察中である.【考察】副乳癌は稀な疾患で, 2003年までに100例の報告がある.腋窩腫瘤の診断では副乳癌を念頭に置いて検索するべきであると考えられた.また,手術においては乳房切除の必要性を検討するため,術前に腫瘤全体の組織学的検索をするべきであると考えられた.
6072 Background: Since 1980s, 18FDG-PET imaging has been used as a modality to improve cancer patient management. Although scan is potentially useful in early detection of disease recurrence after primary treatment patients, its effectiveness screening still unclear. Nevertheless, Japan, very recently, asymptomatic individuals consult PET clinics for screening. The total annual number them exceeded 5000 at the Nishidai clinic, Tokyo, Japan. Methods: From Aug 1, 2002 Jul 31, 2003, 5816...
35歳男性.原因不明の心停止蘇生後の経口気管挿管中に,リユースタイプバイトブロックの金属内筒が脱落し気管支内に迷入した.リユースタイプバイトブロックは,金属内筒をゴムで被覆した構造が多いが,度重なる咬合や滅菌によりゴムの劣化が進み,ゴム部分が破損した場合に内部の金属内筒が脱落する可能性を有している.本症例における金属内筒の脱落した経緯を報告するとともに,その発生原因と対応策について考察した.この症例を契機に,当院ではディスポーザブルタイプバイトブロックの使用に変更した.