A5062043543- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Brain Metastases and Treatment
- Radiation Therapy and Dosimetry
- Childhood Cancer Survivors' Quality of Life
- Testicular diseases and treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Ocular Oncology and Treatments
- Sarcoma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Anesthesia and Neurotoxicity Research
- Fetal and Pediatric Neurological Disorders
- Oral health in cancer treatment
- Cerebrovascular and genetic disorders
- Cerebral Venous Sinus Thrombosis
- Organ Transplantation Techniques and Outcomes
- ATP Synthase and ATPases Research
- S100 Proteins and Annexins
- Renal and related cancers
- Family Support in Illness
- Extracellular vesicles in disease
- Advanced Glycation End Products research
- Caveolin-1 and cellular processes
Children's Memorial Health Institute
2010-2024
Instytut Matki i Dziecka
2010
The aim of this study was to assess the long-term results liver transplantation (LT) in pediatric patients with unresectable hepatoblastoma (HB) or hepatocellular carcinoma (HCC) special reference risk tumor recurrence. We retrospectively analyzed data from 46 HB and 26 HCC who underwent LT between 1990 2022. In patients, we compared outcomes depending on donor type. evaluated impact a number factors recurrence-free survival after LT. Estimated patient 5, 10, 15 years 82%, 73%, 73% group...
The aim of this study was to evaluate the health status children cured from hepatoblastoma. Forty-five patients with hepatoblastoma treated between 1996-2014 were assessed. recorded data included sex, age at diagnosis, disease stage, treatment methods, time since and evaluation domains which performance status, growth development, hearing, cardiovascular, skeletal, gastrointestinal, genitourinary, neurological, hematological function. There 30 boys 15 girls. diagnosis ranged one month 14...
Abstract BACKGROUND Pediatric ependymomas are aggressive central nervous system malignancies arising from the ependymal linings of ventricles and spinal canal. Despite better understanding tumor biology remain therapeutic challenge in pediatric neurooncology. The role chemotherapy remains controversial. Herein, we describe outcomes patients treated at largest center Poland who underwent surgery, pre-irradiation irradiation regardless extent surgical resection. METHODS This retrospective...
Abstract INTRODUCTION Infants constitute approximately 5% of all pediatric LGG. This group is identified as having aggressive course and worse prognosis compared to older children. No specific therapeutic guidelines are yet available for this age group. AIM: Retrospective analysis infants diagnosed treated METHODOLOGY: 25 patients between 2001-2023 were analyzed for: sex, age, tumor location, pathology, treatment outcome. NF1 excluded. RESULTS There 13 boys 12 girls, aged 3 months-11 months,...
Rhabdomyosarcoma (RMS) of the biliary tract is a rare tumor in children, constituting 0.5–0.8% all pediatric RMS. Still, it most common malignancy this location children. Due to its rarity and location, may cause diagnostic treatment difficulties. Above all, there are no therapeutic guidelines specific for location. The aim study was present an analysis our experience with children rhabdomyosarcoma discuss clinical recommendations published literature. A retrospective medical records eight...
BACKGROUND: Malignant pediatric brain tumors constitute a heterogeneic group of central nervous system tumors, and general markers diagnosis prognosis are not available. Recently, panel CD (CD15, CD24, CD29) was used to define increasing neural differentiation embryonic stem cells. Although these have been associated with worse due presence tumor propagating cells, alterations in adhesion migration various cancer types, no studies multiple performed. METHODS: We collected including...
LG-49. LOW GRADE GLIOMA (LGG) OF THE SPINAL CORD. SPECIFIC LOCATION NEEDS TREATMENT Marta Perek-Polnik, Iwona Filipek, Monika Drogosiewicz, Ewa Swieszkowska, Wieslawa Grajkowska, Elzbieta Jurkiewicz, Marcin Roszkowski, and Bozenna Dembowska-Baginska; The Children’s Memorial Health Institute, Warsaw, Poland INTRODUCTION: Spinal cord LGG constitute approximately 3,5% of all locations. No specific therapeutic guidelines are available for this site. AIM: Analysis childhood spinal LGG....
Craniospinal irradiation (CSI) has been a major component of the standard care treatment backbone for childhood medulloblastoma. However, chemotherapy regimens have varied based on protocol, patient age, and molecular subtyping. In one largest studies to date, we analyzed outcomes in children with newly-diagnosed medulloblastoma treated pre-irradiation followed by risk-adapted radiotherapy maintenance chemotherapy. A total 153 patients from Polish Pediatric Neuro-Oncology Group were included...
Abstract Craniospinal irradiation (CSI) has been a major component of the standard care treatment backbone childhood medulloblastoma. However, chemotherapy regimens have varied based on protocol, patient age, and molecular subtyping. In one largest studies to date, we analyze outcomes in children with newly-diagnosed medulloblastoma treated pre-irradiation followed by risk-adapted radiotherapy maintenance chemotherapy. A total 153 patients from Polish Pediatric Neuro-oncology Group were...
Pineoblastoma is a rare, highly aggressive supratentorial tumour, more frequently diagnosed in young children. The prognosis remains poor. AIM: To present own experience with children pineoblastoma. PATIENTS AND 14 pts: 8 girls and 6 boys treated between 1998 2017 were analyzed. 5 pts (36%) under 3 years of age. 7 underwent complete tumour resection, 2-partial resection 5- biopsy. At the onset treatment six patients had disseminated disease. 9 according to protocol for MB HR group (with...
Astroblastoma is a rare CNS tumor of glial origin distinguished from other gliomas in the recent International Classification Tumors Central Nervous System proposed by World Health Organization. We present our experience with 3 astroblastoma patients. Between 2003–2017 among 978 patients tumors treated at Institution (0,3 %) were diagnosed astroblastoma. There 2 girls and 1 boy aged 2.5, 3, 5.5 years. Two had supratentorial tumors, one was located infratentorially. All underwent subtotal...
The aim of the study was to asses QoL in Medulloblastoma (MB) survivors according risk groups. MATERIAL AND Between 2005-2015 132 patients (40 girls, 92 boys aged 2 9/12 – 17 6/12) were treated MB. 44 standard and 88 high risk. Patients SR group received radiotherapy CNS 25Gy whereas HR - 36Gy. Age at analysis 6 1/12 29. Analysis included 5 year EFS/OS assessment of: weight/height percentiles groups age diagnosis, hearing loss, aids, hair loss occurrence posterior fossa syndrome(PFS)....
Abstract BACKGROUND: The last two decades have witnessed several efforts to minimize the adverse sequelae of craniospinal irradiation (CSI), a standard care treatment modality in medulloblastoma. This has been accomplished by adding chemotherapy backbone. use pre-irradiation also previously reported. In one largest studies date, we analyze outcomes children with and high-risk medulloblastoma treated followed reduced-dose radiotherapy SR maintenance chemotherapy. METHODS: Data from Polish...