A5014934065- Luminescence and Fluorescent Materials
- Chromatography in Natural Products
- Biological Activity of Diterpenoids and Biflavonoids
- Natural Compound Pharmacology Studies
- Chemical Synthesis and Analysis
- Cell death mechanisms and regulation
- Ginseng Biological Effects and Applications
- Phytochemistry and Biological Activities
- Synthetic Organic Chemistry Methods
- Advanced biosensing and bioanalysis techniques
- Natural product bioactivities and synthesis
- Click Chemistry and Applications
- Probiotics and Fermented Foods
- Ubiquitin and proteasome pathways
- Thin-Film Transistor Technologies
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Electromagnetic Compatibility and Measurements
- Microbial Metabolites in Food Biotechnology
- Traditional Chinese Medicine Analysis
- Organoboron and organosilicon chemistry
- Nanoplatforms for cancer theranostics
- Synthesis and Catalytic Reactions
- Molecular Sensors and Ion Detection
- Chemical synthesis and alkaloids
Xi'an Jiaotong University
2015-2025
Purdue University West Lafayette
2015-2024
Qingdao Institute of Bioenergy and Bioprocess Technology
2023
Chinese Academy of Sciences
2007-2023
Chengde Medical University
2022
Center for Cancer Research
2015-2019
Tsinghua University
2016-2018
Beijing University of Chinese Medicine
2017
Institute of Science and Technology
2015
China XD Group (China)
2015
Molecules of siloles are almost non-fluorescent but their nanoaggregates highly emissive, exhibiting aggregation-induced emission (AIE). The AIE-active aggregates cytocompatible with living cells, stain cytoplasms HeLa cells indelibly without contaminating another type cell line in a co-culture system, and remain visible for long period time. Detailed facts importance to specialist readers published as "Supporting Information". Such documents peer-reviewed, not copy-edited or typeset. They...
Human serum albumin (HSA) is a major protein component of blood plasma, and its assay obvious value to biological research. We, herein, present readily accessible fluorescent bioprobe for HSA detection quantitation. A nonemissive tetraphenylethene derivative named sodium 1,2-bis[4-(3-sulfonatopropoxyl)phenyl]-1,2-diphenylethene (BSPOTPE) induced emit by HSA, showing novel phenomenon aggregation-induced emission (AIE). The AIE enjoys broad working range (0−100 nM), low limit (down 1 superior...
More than 10% of the people in world still suffer from inadequate access to clean water. Traditional water disinfection methods (e.g., chlorination and ultraviolet radiation) include concerns about formation carcinogenic byproducts (DBPs), pathogen reactivation, and/or excessive energy consumption. Recently, a nanowire-assisted electroporation-disinfection method was introduced as an alternative. Here, we develop new copper oxide nanowire (CuONW)-modified three-dimensional foam electrode...
This letter describes a new design of dual-polarized broadband horn antennas. The bandwidth the designed antenna is from 2 to 26.5 GHz. A novel coaxial line quadruple-ridged waveguide transition introduced improve return loss performance antenna. Measured results for VSWR, isolation, gain, and radiation pattern are presented.
Low-voltage (2 V) electroporation disinfection enabled by CNT sponge achieved highly efficient and reliable cell inactivation.
Abstract Asperamides A ( 1 ) and B 2 ), a sphingolipid their corresponding glycosphingolipid possessing hitherto unreported 9‐methyl‐C 20 ‐sphingosine moiety, were characterized from the culture extract of Aspergillus niger EN‐13, an endophytic fungus isolated marine brown alga Colpomenia sinuosa . The structures elucidated by spectroscopic chemical methods as (2 S ,2′ R ,3 ,3′ E ,4 ,8 )‐ N ‐(2′‐hydroxy‐3′‐hexadecenoyl)‐9‐methyl‐4,8‐icosadien‐1,3‐diol 1‐ O ‐β‐ d ‐glucopyranosyl‐( 2S , 2′R 3R...
Bioassay and ultraperformance liquid chromatography/photodiode array/mass spectrometry (UPLC/PDA/MS) guided isolation of the apoptosis-inducing active metabolites on HeLa-C3 cells from pericarp Garcinia yunnanensis (Guttiferae) yielded five compounds, including new garciyunnanins A (1) B (2). The structures compounds were elucidated by comprehensive nuclear magnetic resonance mass analysis. Garciyunnanin (2), featured with a natural tetracyclic xanthone skeleton derived polyisoprenylated...
Bioassay-guided fractionation of the acetone extract bark Garcinia oblongifolia has resulted in isolation three new xanthones, oblongixanthones A−C (1−3), polyprenylated benzoylphloroglucinols, oblongifolins E−G (4−6), and 12 known compounds. Oblongifolins I (5) J (6) are first natural products that have similar structural features to those two oxidation garcinol. The structures compounds 1−6 were characterized by spectroscopic data interpretation. All isolates assayed for their...
Oblongifolin C (OC) was identified as a potent apoptosis inducer from an herbal plant, Garcinia yunnanensis, during our previous bioassay-guided drug screening. In this study, we investigated the signaling pathways through which OC activated in HeLa cells. We also compared IC(50) values of with that etoposide, paclitaxel and vinblastine multiple cancer cell lines including HER2 P-glycoprotein overexpressing addition, vivo antitumor effect studied nude mice model. Our results showed induced...
The deubiquitinase (DUB) ubiquitin C-terminal hydrolase L1 (UCHL1) is expressed primarily in the central nervous system under normal physiological conditions. However, UCHL1 overexpressed various aggressive forms of cancer with strong evidence supporting as an oncogene lung, glioma, and blood cancers. In particular, level expression these cancers correlates increased invasiveness metastatic behavior, well poor patient prognosis. Although considered potential a therapeutic target, there...
In this study, functional lactic acid bacteria (LAB) specific for vegetable fermentation were screened from Chinese sauerkraut brine by designing purpose media. The selected LAB strains showed excellent tolerance to high concentrations of bile salt and acids. They can also survive passage through the simulated gastric fluid may be able reach intestine. Through performance measurements fermentation, one these strains, NCU116 was found have best ability, further subjected a series analyses...
The inactivation of pathogens in liquids has broad applications, ranging from water disinfection to food pasteurization. However, common cell methods (e.g., chlorination, ultraviolet radiation and thermal treatment) have significant drawbacks such as carcinogenic byproduct formation, energy intensiveness and/or nutrient structure destruction. Here, we fabricated a new approach address these challenges by applying low-voltage electroporation (EDC) investigate the critical mechanisms transport...
Mutarotation of O-glycans and O-glycosides has long been well-established exploited in the stereocontrolled chemical synthesis O-glycosides, while few examples C-glycoside anomerization are known to date. During development a simple iridium catalyst-promoted α-stereoselective C-glycosylation 2-indoly-pyridine with glycal donors, we serendipitously discovered occurrence 2-deoxy-C-glycoside anomerization, enabling α-to-β configuration conversion. Control experiments density functional theory...
A new aggregation-induced emission (AIE) compound 1,2-bis[4-(isothiocyanatomethyl)phenyl]-1,2-diphenylethene (2) was synthesized for use in SDS-PAGE. The molecule is practically nonemissive solution but becomes highly emissive after reacting with the amine groups of proteins by either prestaining or poststaining method. sensitivity 2 achieved method same as that Coomassie brilliant blue (CBB), while observed higher than CBB. Excellent linear responses amount protein were obtained both cases....