A5100415206- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Kidney Stones and Urolithiasis Treatments
- Renal cell carcinoma treatment
- SARS-CoV-2 and COVID-19 Research
- Gastric Cancer Management and Outcomes
- Autophagy in Disease and Therapy
- PI3K/AKT/mTOR signaling in cancer
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Autoimmune Bullous Skin Diseases
- Extracellular vesicles in disease
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Photodynamic Therapy Research Studies
- Chronic Lymphocytic Leukemia Research
- Renal Diseases and Glomerulopathies
- Head and Neck Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Medicinal Plants and Neuroprotection
- Esophageal Cancer Research and Treatment
- Chronic Kidney Disease and Diabetes
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
Central South University
2024-2025
Ministry of Education of the People's Republic of China
2025
Zhejiang University
2021-2025
Second Affiliated Hospital of Zhejiang University
2025
The First Affiliated Hospital, Sun Yat-sen University
2022-2024
Sun Yat-sen University
2022-2024
First People's Hospital of Foshan
2023
First Affiliated Hospital Zhejiang University
2019-2021
Zhongshan People's Hospital
2008-2011
Jiujiang First People's Hospital
2008
Abstract Silica nanoparticles (SiNPs) have been reported to induce pulmonary fibrosis (PF) with an unknown mechanism. Recently, the activation of autophagy, a lysosome-dependent cell degradation pathway, by SiNPs has identified in alveolar epithelial cells (AECs). However, underlying mechanism and relevance SiNPs-induced autophagy development PF remain elusive. Here, we report that dysfunction subsequent apoptosis AECs are involved PF. engulfed enhance autophagosome accumulation both vivo...
To investigate the ability of body shape index (ABSI), roundness (BRI), waist circumference (WC), mass (BMI), waist-to-hip ratio (WHR), waist-to-height (WHtR), and adiposity (BAI) for predicting non-adipose cardio-metabolic risk.A total 17,360 Chinese subjects aged 18-95 years old who escaped cardiovascular disease (CVD) or diabetes were recruited in cross-sectional study. Anthropometric biochemical parameters assessed. Receiver operating characteristic curve (ROC) multinomial logistic...
<title>Abstract</title> Background Despite surgery is the recommended treatment for oral cancer patients, little known about intraoperative blood loss in this population. This study sought to identify risk factors haemorrhage resection and free flap reconstruction surgery, develop a machine learning-based predictive model. Methods retrospective cohort included patients with who underwent fibular at tertiary hospital. Demographic clinical parameters were selected using Recursive Feature...
Abstract Background Recently studies had showed that the amygdala may take part in cognitive impairment schizophrenia (SC). However, mechanism is still unclear, so we explored relationship between resting state magnetic resonance imaging (rsMRI) signal and function, to provide a reference for follow-up study. Methods We collected 59 drug-naïve SCs 46 healthy controls (HCs) from Third People’s Hospital of Foshan. The rsMRI technique automatic segmentation tool were used extract volume...
Abstract Background The severity of COVID-19 associates with the clinical decision making and prognosis patients, therefore, early identification patients who are likely to develop severe or critical is in practice. aim this study was screen severity-associated markers construct an assessment model for predicting COVID-19. Methods 172 confirmed were enrolled from two designated hospitals Hangzhou, China. Ordinal logistic regression used markers. Least Absolute Shrinkage Selection Operator...
Autosomal dominant tubulointerstitial kidney disease due to UMOD mutations (ADTKD-UMOD) results in chronic interstitial nephritis, which gradually develops into end-stage renal disease. It is believed that the accumulation of mutant uromodulin causes endoplasmic reticulum (ER) stress, then leads damage. But underlying mechanism remains unclear. To find ADTKD-UMOD patients, gene screening was performed 26 patients with unexplained during past 10 years our department, and among them three...
This study aimed to investigate the prognostic value of lymph node ratio (LNR) in patients with locally advanced gastric cancer who received neoadjuvant chemotherapy.We retrospectively enrolled treated chemotherapy and curative surgery at First Affiliated Hospital Zhejiang University from 2004 2015 as cohort. Patients same inclusion criteria 2016-2017 were validation Kaplan-Meier curves assessed using log-rank test analyze differences overall survival (OS). Multivariate analysis was...
<title>Abstract</title> <bold>Objective: </bold>Effects of sevoflurane and propofol anesthesia on cardioprotective postoperative recovery were compared in patients with off-pump coronary bypass surgery. <bold>Methods: </bold>Preoperative myocardial enzymes, other blood biochemical indexes clinical outcome retrospectively analyzed. <bold>Results: </bold>Compared the group, serum concentration troponin I (1.19 ± 2.68 ng/mL vs 0.24 0.52 ng/mL, p=0.018) brain natriuretic peptide (713.19 849.31...
Objectives This study aimed to evaluate the clinical and prognostic characteristics of primary gastric gastrointestinal stromal tumors (GIST).
Abstract Background: The severity of COVID-19 associates with the clinical decision making and prognosis patients, therefore, early identification patients who are likely to develop severe or critical is in practice. aim this study was screen severity-associated markers construct an assessment model for predicting COVID-19. Methods: 172 confirmed were enrolled from two designated hospitals Hangzhou, China. Ordinal logistic regression used markers. Least Absolute Shrinkage Selection Operator...
Objective To evaluate the effect and safety d sorafenib in treatment of patients with metastatic renal cell carcinoma.Methods 40 carcinoma,were given tablets methanesulfonate treatment,the initial dose 800mg/d,bid,continuous administration 21d,stopping 7d,The adverse reactions,efficacy immunohistochemistry results were observed.Results cases carcinoma not found complete remission (CR) partial (PR) ; The 32 stable disease (SD)(80.0％ ) 8 ( 20.0％ PD; incidence 28 70.0％ digestive system;...
Objectives To assess the safety ,feasibility and superiority of minimally invasive percutaneous nephrolithotomy (mini-PCNL) with ureteroscopic holmimium.Methods The data 20 patients renal calculi who had undergone mimi-PCNL from August 2004 to April 2008 were retrospectively analyzed.Build up tract mini-PCNL under guide B-ultrasound or C x-ray machine ,All treated by holmimium:YAG laser lithotripsy.Results total stone-free rate was 90%.And no complications such as severe bleeding urinary...
Abstract Background: The severity of COVID-19 associates with the clinical decision making and prognosis patients, therefore, early identification patients who are likely to develop severe or critical is in practice. aim this study was screen severity-associated markers construct an assessment model for predicting COVID-19. Methods: 172 confirmed were enrolled from two designated hospitals Hangzhou, China. Ordinal logistic regression used markers. Least Absolute Shrinkage Selection Operator...
This 60-case report deals with the application of photodynamic therapy in treatment and diagnosis cancer. The cancer is a development from late seventies. Since March 1989, we have diagnosed treated 60 patients this therapy. Our results show that positive rate 100 percent, effective 75 percent.