Abstract Graphene is used as a growth template for van der Waals epitaxy of organic semiconductor (OSC) thin films. During the synthesis and transfer chemical‐vapor‐deposited graphene on target substrate, local inhomogeneities in graphene—in particular, nonuniform strain field template—can easily form, causing poor morphology crystallinity OSC Moreover, introduces pseudo‐electric graphene. Here, study investigates how strain‐induced affect self‐assembly π‐conjugated molecules it....

This study investigates the influence of graphene's surface properties on orientation pentacene molecules in organic thin films. The roughness and strain graphene destabilize lying-down configurations, promoting nucleation with standing-up molecular orientations.

Dengue is listed as a neglected tropical disease by the Center for Disease Control and Preservation, there are insufficient integrated surveillance strategies, no effective treatment, limited licensed vaccines. Consisting of four genetically distinct serotypes, dengue virus (DENV) causes serious life-threatening infections due to its complexity. Antibody-dependent enhancement pre-existing cross-reactive well homotypic antibodies further worsens clinical symptoms dengue. Thus, vaccine...

Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts effects through the transformation of saponin into metabolites by intestinal microbiota. Given that conditions and microflora vary among individuals, orally administered red likely may individuals.To overcome this variation produce homogeneously effective ginseng, we evaluated probiotic-fermented in mouse model.The efficacy was assessed ICR mice after...

Direct-acting agents against viral components are considered as the most promising candidates for successful antiviral therapeutics. To date, no direct-acting drugs exist treatment dengue virus (DV) infection, which can develop into life-threatening diseases. RNA-dependent RNA polymerase (RdRp), an virus-specific enzyme highly conserved among various families, has been known broad-range drug target. Here, we developed RNA-based graphene biosensor system [RNA nano-graphene oxide (RANGO)] to...

Dengue is a rapidly spreading mosquito borne tropical viral disease affecting hundreds of millions people across the globe annually. The dengue virus (DENV) includes four genetically distinct serotypes that cause serious life-threatening infections, including hemorrhagic fever/dengue shock syndrome. vaccine development complicated by possibility vaccine-enhanced severe due to antibody-dependent enhancement pre-existing cross-reactivity, as well homotypic antibodies. Thus, an efficacious...

Dengue virus (DENV), an arbovirus transmitted by mosquitoes, causes infectious diseases such as dengue fever, hemorrhagic and shock syndrome. Despite the dangers posed DENV, there are no approved antiviral drugs for treatment of DENV infection. Considering potential a global outbreak, rapid development agents against infections is crucial preemptive measure; thus, selection apparent drug targets, viral enzymes involved in life cycle, recommended. Helicase, target enzyme that unwinds...

Tmem173 was identified as a growth inhibitor associated with major histocompatibility complex (MHC) class II and potential stimulator for IFN‐β, an innate immune inducer negative feedback controller RANKL‐induced osteoclast differentiation of monocytic macrophage cells. In this study, we confirmed that transmembrane protein 173 (Tmem173) overexpression inhibited the expression osteoclast‐specific genes, tartrate‐resistant acid phosphatase (TRAP), cathepsin K, matrix metalloproteinase‐9...

Abstract The high defect density and inferior crystallinity remain great hurdles for developing highly efficient stable Sn‐based perovskite solar cells (PSCs). 2D/3D heterostructures show strong potential to overcome these bottlenecks; however, a limited diversity of organic spacers has hindered further improvement. Herein, novel alicyclic spacer, morpholinium iodide (MPI), is reported structurally stabilized perovskite. Introducing secondary ammonium ether group in 2D enhances its rigidity,...

Dengue virus (DENV) comprises four serotypes in the family Flaviviridae and is a causative agent of dengue-related diseases, including dengue fever. fever generally self-limited febrile illness. However, secondary infection patients with suboptimal antibody (Ab) response provokes life-threatening severe hemorrhagic or shock syndrome. To develop potent candidate subunit vaccine against DENV infection, we developed EDII-cEDIII antigen, which contains partial envelope domain II (EDII) fusion...

Ophiocordyceps sinensis is a natural fungus that has been valued as health food and used in traditional Chinese medicine for centuries.The parasitic colonizes insect larva.Naturally occurring O. thrives at high altitude cold grassy alpine meadows on the Himalayan mountain ranges.Wild becoming increasingly rare its habitat, price limits use clinical practice.Therefore, development of standardized alternative great focus research to allow medicine.To develop an wild Ophiocordyceps, refined...

Ginsenosides are biologically active components of ginseng and have various functions. In this study, we investigated the immunomodulatory activity a product generated from powder (GP) via enzymatic bioconversion. This product, General Bio compound K-10 mg solution (GBCK10S), exhibited increased levels minor ginsenosides, including ginsenoside-F1, K, Y.The properties GBCK10S were confirmed using mice human natural killer (NK) cell line. We monitored expression molecules involved in immune...

The objective of this study was to evaluate the ability acoustic structure quantification (ASQ) diagnose thyroiditis.The echogenicity 439 thyroid lobes, as determined using ASQ, quantified and analyzed retrospectively. Thyroiditis categorized into five subgroups. results were presented in a modified chi-square histogram mode, average, ratio, blue average. We cutoff values ASQ from ROC analysis detect differentiate thyroiditis normal gland. obtained data on sensitivity specificity distinguish...

Solitary fibrous tumor (SFT) is a well-known composed of spindle cells found most commonly in the pleura. Recently, accounts their rare occurrence at other sites, including head and neck area, have been reported. The parapharyngeal space location even for SFTs, thus, could be confused with variety tumors that can originate this area. Here, we report case SFT originating from post-styloid discuss possible differential diagnosis on radiographic findings.

Abstract Fucoidan is a sulfated polysaccharide that primarily extracted from brown seaweeds which has been broadly studied in recent years due to its numerous biological properties, including anticoagulant, antithrombotic, antitumor, and antiviral activities. In this study, we investigated whether fucoidan the ability attenuate expression of pro-inflammatory mediators such as NO, prostaglandin E2 (PGE2), TNF-α, IL-1β LPS-stimulated RAW 264.7 macrophage cells. inhibited LPS-induced PGE2,...

In the rapidly evolving landscapes of Wireless Sensor Networks (WSNs) and Internet Things (IoT), integration deep learning techniques into routing structures is emerging as a significant advancement. WSNs IoT systems are pivotal in real-time monitoring control across various sectors, including environmental monitoring, industrial automation, healthcare, smart cities, more. These networks rely heavily on efficient data collection seamless exchange, facilitated by interconnected nodes diverse...

The rapidly growing number of AI-enabled applications is driving the need for development energy efficient computing hardware that can handle massive amount computations required neural network operation. As one promising approaches processing data within memory, Logic-in-memory parallel execution reconfigurable logic operation memory allows fast and computations. For realizing logic-in-memory hardware, implementing practical functions with high density critical concern. Here, we demonstrate...