A5103280786- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Genetic factors in colorectal cancer
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Metastasis and carcinoma case studies
- Cancer-related gene regulation
- Cancer-related Molecular Pathways
- RNA modifications and cancer
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Treatments and Mutations
- Cancer, Hypoxia, and Metabolism
- Cancer Genomics and Diagnostics
- Head and Neck Cancer Studies
- Colorectal Cancer Surgical Treatments
- Cancer Research and Treatments
- Nutrition and Health in Aging
- Lung Cancer Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Peroxisome Proliferator-Activated Receptors
- Tracheal and airway disorders
- Cancer Cells and Metastasis
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
National Hospital Organization Kyushu Cancer Center
2016-2025
National Kyushu Medical Center
2021
National Institute of Diabetes and Digestive and Kidney Diseases
2019
ProQuest (United States)
2019
Bioengineering Center
2019
Kyushu University
2008-2017
Toho University
2016
Toho University Omori Medical Center
2016
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
2015
Kumamoto University
2013
Programmed death‐ligand 1 ( PD ‐L1) plays a crucial role in the host immune system cancer progression. The gene promoter region of ‐L1 also contains binding site for ZEB 1, transcription factor related to epithelial‐mesenchymal transition EMT ). purpose this study was clarify relationship between and its clinical importance esophageal squamous cell carcinoma ESCC expression at tumor invasive front examined by immunohistochemistry resected specimens from 90 patients with who underwent surgery...
The salivary microbiota is constantly swallowed and delivered to the digestive tract. These bacteria may be associated with gastrointestinal diseases. This case-control study examined in patients tract cancer (DTC) evaluated their differential distribution based on sites. We collected saliva samples from 59 any part of (tongue/pharynx, esophagus, stomach, large intestine) 118 age- sex-matched control subjects. There was no significant difference periodontal status between DTC subjects (P =...
The registration committee for esophageal cancer in the Japan Esophageal Society (JES) has collected patients' characteristics, treatment, and outcomes of patients who underwent any treatment during 2015 Japan.We analyzed data had visited participating hospitals 2015. We using National Clinical Database with a web-based collection system. used Japanese Classification Cancer 10th edition by JES TNM classification Union International Control (UICC) staging.A total 9368 cases were registered...
Smoking and drinking habits as well family history were examined in 143 men with esophageal cancer, including 30 who had associated second cancers of the upper aerodigestive tract (UADT) 113 did not. The risk UADT main lesions esophagus was evaluated, using odds ratios (ORs). As a result, ORs for current smoking 5.3 7.6 respectively. significantly increased to 12.7 14.7 heavy smokers drinkers Furthermore, cancer also (8-fold) patients close relatives compared those without any cancer....
Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function p53. However, there are some discrepancies between the result immunohistochemistry mutation analysis. This study attempted find new definition by its pattern. TP53 gene analysis were performed in 148 gastric cancer patients. Also SNP-CGH array was conducted four cases. Positive observed 88 (59.5%) tumors. Tumors with positive showed malignant features compared negative Mutation 29 (19.6%) tumors...
Neuroendocrine carcinoma (NEC) of the esophagus is a rare and highly aggressive disease but biological features are poorly understood. The objective this study was to analyze clinicopathological immunohistochemical NEC esophagus.Fourteen patients diagnosed with from 1998 2013 were included in study. Clinicopathologic features, therapeutic outcomes results analyzed.Eleven out 14 cases showed protruding or localized type without ulceration. Only three negative for both lymph node organ...
Both internal and external oxidative stresses act on DNA can induce carcinogenesis. 8-hydroxydeoxyguanosine (8-OHdG) is an indicator of stress it leads to transversion mutations 8-OHdG excision-repaired by glycosylase (OGG1). The purpose this study clarify the effect damage repair enzymes esophageal levels OGG1 were immunohistochemically evaluated in resected specimens, including squamous cell carcinoma (SCC) 97 patients with cancer. Higher normal epithelium associated a higher smoking index...