A5041292026- Tracheal and airway disorders
- Tuberculosis Research and Epidemiology
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Respiratory Support and Mechanisms
- Pleural and Pulmonary Diseases
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related gene regulation
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Infectious Diseases and Tuberculosis
- Medical Imaging and Pathology Studies
- Advanced biosensing and bioanalysis techniques
- Lung Cancer Research Studies
- Bacteriophages and microbial interactions
- Cancer-related molecular mechanisms research
- Intensive Care Unit Cognitive Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Electrochemical Analysis and Applications
- Sepsis Diagnosis and Treatment
- Trauma Management and Diagnosis
- Epigenetics and DNA Methylation
The Affiliated Yongchuan Hospital of Chongqing Medical University
2016-2025
Chongqing Medical University
2016-2025
Shanxi Medical University
2025
The Ohio State University Wexner Medical Center
2024
The Ohio State University
2024
University of Oxford
2023
Creative Commons
2023
Zhejiang Industry Polytechnic College
2023
Changzhou No.2 People's Hospital
2019
Yokohama City University
2019
The clinical characteristics of the patients with COVID-19 complicated by pneumothorax have not been clarified.To determine epidemiology and risks in critically ill COVID-19.Retrospectively collecting analysing medical records, laboratory findings, chest X-ray CT images 5 pneumothorax.The incidence was 10% (5/49) ARDS, 24% (5/21) receiving mechanical ventilation, 56% (5/9) requiring invasive 80% (4/5) died. All were male aged ranging from 54 to 79 years old. Pneumothorax most likely occur 2...
Tuberculosis (TB) remains a serious global public health problem in the present. TB also affects other sites (extrapulmonary tuberculosis, EPTB), and accounts for significant proportion of tuberculosis cases worldwide. In order to comprehensively understand epidemiology EBTB China, improve early diagnosis treatment, we conducted large-scale multi-center observational study assess demographic data prevalence common EPTB inpatients, further evaluate concurrent with Pulmonary (PTB) associations...
Our pilot study suggested that noninvasive ventilation (NIV) reduced the need for intubation compared with conventional administration of oxygen on patients "early" stage mild acute respiratory distress syndrome (ARDS, PaO2/FIO2 between 200 and 300). To evaluate whether early NIV can reduce invasive in pneumonia-induced ARDS. Prospective, multicenter, randomized controlled trial (RCT) through a Venturi mask. Primary outcome included numbers who met criteria. Two hundred subjects were to (n =...
Mortality is high among severe patients with 2019 novel coronavirus-infected disease (COVID-19). Early prediction of progression to cases needed. We retrospectively collected COVID-19 in two hospital Chongqing from 1st January 29th February 2020. At admission, we the demographics and laboratory tests predict whether patient would progress hospitalization. Severe case was confirmed when one following criteria occurred: (a) dyspnea, respiratory rate ≥30 breaths/min, (b) blood oxygen saturation...
Malnutrition negatively affects patients with chronic obstructive pulmonary disease (COPD). This study aimed to explore the potential association between malnutrition, as defined by Geriatric Nutritional Risk Index (GNRI), and all-cause mortality in COPD using National Health Nutrition Examination Survey (NHANES).The data of 579 adults during NHANES 2013-2018 were analysed. Each patient was assigned one two groups according GNRI values: normal nutritional status (GNRI>98) malnutrition...
Poly (ADP‐ribose) polymerase (PARP) inhibitors have demonstrated great promise in the treatment of patients with deficiencies homologous recombination (HR) DNA repair, such as those loss BRCA1 or BRCA2 function. However, emerging studies suggest that PARP inhibition can also target HR‐competent cancers, non‐small‐cell lung cancer (NSCLC), and therapeutic effect may be improved by combination chemotherapy agents. In our study, it was found talazoparib (BMN‐673) olaparib (AZD‐2281) both had...
AimsA high proportion of all patients with tuberculosis (TB) present extrapulmonary TB (EPTB), including concurrent EPTB involving more than one lesion site. However, previous reports only characterized lesions single-site cases. This study aimed to investigate epidemiological characteristics and association rules cases in China.MethodsAn observational multi-centre 208,214 was undertaken China from January 2011 December 2017. Multi-variable logistic regression analysis used identify...
Assessment of lung function is essential for the early screening chronic airway diseases (CADs). Nevertheless, it still not widely used diagnosing CADs in epidemiological or primary care settings. Thus, we data from US National Health and Nutrition Examination Survey (NHANES) to discuss relationship between serum uric acid/serum creatinine (SUA/SCr) ratio general adults gain role SUA/SCr assessment abnormalities.
The relationship between albumin-corrected anion gap (ACAG) and in-hospital mortality in critically ill patients with COPD remains unclear. This study investigated the association ACAG levels risk of COPD. A retrospective cohort study. uses data from Medical Information Mart for Intensive Care (MIMIC-IV) database. receiver operating characteristic (ROC) curve was used to determine optimal threshold ACAG, participants were divided into two categories based on this threshold. primary outcome...
BACKGROUND Among all forms of heterotopic ossification, mesenteric ossification (HMO) is rare, with fewer than 100 reported cases to date. Postoperative early small bowel obstruction caused by HMO even rarer, presenting extremely high surgical risks, the potential for multiple surgeries, and a poor prognosis. There have been no conservative treatment resolving such postoperative obstruction. CASE SUMMARY A 57-year-old male presented severe shortly after undergoing open radical resection...
Abstract Background: Multi-Cancer Early Detection (MCED) represents a promising approach with the potential for high sensitivity in detecting rare tumor-derived signals blood. However, contamination from adjacent samples or environmental sources poses significant challenges that can compromise accuracy of these results. Current detection methods primarily designed tissue samples, leaving notable gap methodologies assessing low-level cfDNA targeted methylation sequencing data The include...
Background Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality, particularly among critically ill patients. Despite the well-established role inflammation in COPD pathogenesis, prognostic significance systemic immune-inflammatory index (SII) these patients remains unclear. This study aimed to investigate relationship between SII mortality risk with COPD. Methods retrospective observational cohort utilized data from 3,291 extracted Medical Information Mart...