A5100745329- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Hernia repair and management
- Intestinal and Peritoneal Adhesions
- Cancer Genomics and Diagnostics
- Surgical Sutures and Adhesives
- Anorectal Disease Treatments and Outcomes
- Gastric Cancer Management and Outcomes
- Appendicitis Diagnosis and Management
- Cancer Cells and Metastasis
- Uterine Myomas and Treatments
- Abdominal Surgery and Complications
- Gastrointestinal disorders and treatments
- Cell death mechanisms and regulation
- Gynecological conditions and treatments
- Anatomy and Medical Technology
- Diverticular Disease and Complications
- Endometriosis Research and Treatment
- Abdominal Trauma and Injuries
- Metastasis and carcinoma case studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Research and Treatments
Gachon University Gil Medical Center
2013-2025
Gachon University
2013-2025
NIHR Birmingham Biomedical Research Centre
2023
University of Birmingham
2023
National University of Avellaneda
2023
ESCP Business School
2023
ESCP Business School
2023
GTx (United States)
2021
Dynamic Boosting Systems (United Kingdom)
2014
Charles R. Drew University of Medicine and Science
2011
Accurate and physiologically meaningful biomarkers for human aging are key to assessing antiaging therapies. Given ethnic differences in health, diet, lifestyle, behavior, environmental exposures, even average rate of biological aging, it stands reason that clocks trained on datasets obtained from specific populations more likely account these potential confounding factors, resulting an enhanced capacity predict chronological age quantify age. Here, we present a deep learning-based...
This study aimed to investigate the clinical significance of E-cadherin expression levels in colorectal cancer tissues and explore relationship between tumor node metastasis (TNM) stage. The goal was establish a more accurate prognostic prediction for patients by analyzing alongside TNM staging. examined dividing them into groups based on levels. It then assessed their 5-year event-free survival (EFS) disease-specific (DSS) hazard ratios (HRs). Additionally, prognosis analyzed combining with...
The role of the radiofrequency ablation (RFA) in treatment solitary liver metastasis has not been established yet. Both hepatic resection (HR) and RFA have used increasingly colorectal metastases.A systemic review was performed to determine impact modality on recurrence patterns, disease-free survival, overall survival (OS) rates.Solitary metastases were treated by HR 116 patients (75.8%) 37 (24.2%) with RFA. Prognostic factors, rate, rates analyzed. cumulative 3-year 5-year local free...
Approximately 50% of patients with primary colorectal carcinoma develop liver metastases. Understanding the genetic differences between colon cancer and their metastases to is essential for devising a better therapeutic approach this disease. We performed whole exome sequencing copy number analysis 15 triplets, each comprising normal tissue, carcinoma, its synchronous matched metastasis. analyzed similarities in regards somatic mutations alterationss. The genomic profiling demonstrated...
The most reliable prognostic factor in colon cancer is the TNM classification. objective of this study was to assess and compare role tumor-infiltrating lymphocytes (TILs) stage II cancer.Immunohistochemistry used density TILs that were positive for cluster differentiation 3 (CD3) (T-cell coreceptor), CD45 isoform RO (CD45RO) (protein tyrosine phosphatase), nuclear transcription forkhead box P3 (FOXP3), CD25 (a type I transmembrane protein) according tumor site (intraepithelial stromal)...
In Brief Objective: To compare surgical outcomes and quality of life between single-port laparoscopic appendectomy (SPLA) conventional (CLA) in patients with acute appendicitis. Background: A prospective randomized single center study was performed to the outcome SPLA CLA Methods: total 248 were randomized, but because 18 withdrawals, 224 is analyzed, 116 114 SPLA. Results: There no significant difference overall complication rate (P = 0.470). differences infectious complications group...
// Seung Tae Kim 1, * , Won-Suk Lee 2, Richard B. Lanman 3 Stefanie Mortimer Oliver A. Zill Kyoung-Mee 4, 5 Kee Taek Jang Seok-Hyung Se Hoon Park 1 Joon Oh 4 Young Suk Ho Yeong Lim Helmy Eltoukhy Won Ki Kang Woo Yong 6 Hee-Cheol Keunchil Jeeyun AmirAli Talasaz Division of Hematology-Oncology, Department Medicine, Samsung Medical Center, Sungkyunkwan University School Seoul, Korea 2 Surgery, Gil Gachon University, Incheon, Guardant Health Inc., Redwood City, CA, USA The Innovative Cancer...
Background: Until now, studies on colorectal cancer (CRC) have focused clinicopathological characteristics based location without considering sex differences. However, as men and women fundamentally different physiological characteristics, research results in the clinical field are limited. We aimed to elucidate differences between right-sided CRC (RCC) left-sided (LCC) according sex. Methods: classified 1492 South Korean patients with no history of colon surgery July 2005 June 2015 tumor...
Colorectal cancer (CRC) is widely recognized for its high prevalence and significant mortality rates, purine metabolism has been serving as a potential therapeutic target. However, not yet validated prognostic marker through immunohistochemical analysis. In this study, we utilized combination of bulk transcriptome analysis, immunohistochemistry (IHC), single‐cell RNA sequencing (scRNA‐seq) to assess the clinical relevance in CRC. Low expression levels five metabolism‐related genes— ADSL ,...
Purpose: Organ transplantation is considered the definitive treatment for end-stage organ disease. However, scarcity of donor organs compared to number patients awaiting transplants a major barrier. This study aimed assess impact regional trauma center on procurement and provide basis future collaboration between centers transplant centers.Methods: retrospective analyzed donors after brain death over 20-year period from January 1, 2003, December 31, 2022. It before establishment center, as...
Abstract The aim of this study was to compare human epidermal growth factor 2 ( HER 2) status in primary colorectal cancer and paired liver or lung metastasis. Gene amplification has been intensively evaluated contemporary oncology, especially breast stomach cancer. knowledge metastatic sites may be potential value for therapeutic decision making colon assessed by fluorescence situ hybridization FISH ) immunohistochemistry IHC 94 with corresponding metastases. present 19 the 188 (10.1%) both...
Colon cancer is prone to distant metastases other sites and the risk of recurrence relatively high. Therefore, identification liver metastasis-related factors important for diagnosis or treatment colon cancer. The aim this study was identify that are differentially expressed in synchronous solitary metastasis compared primary cancer.Tissues associated with five patients were used mass spectrometry. Identified proteins validated by western blotting. silico analysis performed using STRING...
Watson for oncology (WFO) is a cognitive computing system providing decision support. We evaluated the concordance rates between treatment options determined by WFO and those multidisciplinary team (MDT).We reviewed medical charts of patients diagnosed with colorectal cancer who visited MDT at single tertiary center from November 2016 to April 2017. classified specific into three categories: 'Recommended', 'For consideration', 'Not recommended'. Concordance WFO- MDT-determined chemotherapy...
Physicians and oncology nurses must continue to update their knowledge on treatment treatment-related side effects, while searching for effective methods prevent or manage effects. The objective of our study was describe the incidence response hand-foot syndrome (HFS) compliance with patients stage IIB, IIIA, IIIB, IIIC colon cancer that were treated capecitabine alone as adjuvant therapy.Between September 2005 2006, 84 fulfilled inclusion criteria included in this retrospective analysis...
Selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists are reported to have potent antiemetic effects for postoperative nausea and vomiting (PONV). The purpose of this study was prospectively evaluate the efficacy palonosetron, granisetron, ramosetron prevention PONV in patients undergoing laparoscopic gynecologic surgery. In prospective, randomized observational study, 105 healthy female who were laparocopic hystectomy under general anaesthesia enrolled (clinical trial number:...