A5007633586- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Endometriosis Research and Treatment
- Plant nutrient uptake and metabolism
- Gynecological conditions and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Nitrogen and Sulfur Effects on Brassica
- Cardiac Arrhythmias and Treatments
- Uterine Myomas and Treatments
- Potassium and Related Disorders
- Plant Molecular Biology Research
- Infective Endocarditis Diagnosis and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Valve Diseases and Treatments
- Parathyroid Disorders and Treatments
- Traditional Chinese Medicine Analysis
- Climate Change and Health Impacts
- Gut microbiota and health
- Reproductive Biology and Fertility
- Electrolyte and hormonal disorders
- Air Quality and Health Impacts
- Traditional Chinese Medicine Studies
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
Sun Yat-sen University
2012-2025
The First Affiliated Hospital, Sun Yat-sen University
2012-2025
Southwest University
2022-2025
Shanxi Agricultural University
2023-2024
Xi'an Chest Hospital
2024
Peking University Shenzhen Hospital
2019-2023
Peking University
2015-2022
Kavli Institute for Theoretical Sciences
2022
Shaanxi Provincial People's Hospital
2022
National Health and Family Planning Commission
2021
Recent studies suggested that gut microbiota was involved in the development of coronary artery disease. However, changes following acute myocardial infarction (AMI) remain unknown. In this study, a total 66 male Wistar rats were randomly divided into control, AMI and SHAM groups. The controls (n = 6) sacrificed after anesthesia. model built by ligation left anterior descending artery. groups at 12 h, 1 d, 3 7 d 14 post-operation respectively. Gut analyzed 16S rDNA high throughput...
This study aimed to compare the ultra-long gonadotropin-releasing hormone agonist (GnRH-a) protocol and long GnRH-a during in vitro fertilization (IVF) or intracytoplasmic sperm (ICSI) treatment on fertility outcomes women with adenomyosis.This was a retrospective cohort study. From January 2011 May 2018, total of 371 fresh IVF/ICSI cycles were included. Among included, 237 212 underwent protocol, while 134 116 protocol. The rates implantation, clinical pregnancy per embryo transfer, live...
Background Atrial fibrillation (AF) significantly increases the ischemic stroke risk. However, relationship between age at diagnosis of AF and subsequent risk remains poorly understood. Methods Results We analyzed data from 5 prospective cohorts: ARIC (Atherosclerosis Risk in Communities) study, CHS (Cardiovascular Health Study), CARDIA (Coronary Artery Development Young Adults), MESA (Multi‐Ethnic Study Atherosclerosis), Framingham Heart (including Offspring cohort Third‐Generation...
Phosphorus (P) is an essential macronutrient for Brassica napus L. growth and development, mainly acquired from the soil as phosphate (Pi). However, there no research on system analysis of Pi utilization related genes (PURs) in B. yet. In this study, 285 PURs were identified genome, including 4 transcription factor (TF) gene families (83 genes) 17 structural (202 genes). Subcellular localization showed that proteins encoded by located nucleus (~ 46.0%) cell membrane 36.5%). Chromosome...
Nitrate transporter 2 (NRT2) plays an essential role in Nitrogen (N) uptake, transport, utilization, and stress resistance. In this study, the NRT2 gene family two sequenced Brassica napus ecotypes were identified, including 31 genes 'Zhongshuang11' (BnaZSNRT2s) 19 'Darmor-bzh' (BnaDarNRT2s). The candidate divided into three groups (Group I-III) based on phylogenetic analyses, supported by a conserved intron-exon structure each group. Collinearity analysis revealed that large expansion of...
Background Polypharmacy is common in heart failure (HF), whereas its effect on adverse outcomes patients with HF preserved ejection fraction (HFpEF) unclear. Aim To evaluate the prevalence, prognostic impacts, and predictors of polypharmacy HFpEF patients. Design setting A retrospective analysis performed Americas region (including US, Canada, Argentina, Brazil) symptomatic a left ventricular ≥45% TOPCAT (Treatment Preserved Cardiac Function Heart Failure an Aldosterone Antagonist) trial,...
Transcribed ultraconserved regions (T-UCRs) are a novel class of long noncoding RNAs transcribed from UCRs, which exhibit 100% DNA sequence conservation among humans, mice, and rats. However, whether T-UCRs regulate cardiac hypertrophy remains unclear. We aimed to explore the effects on hypertrophy. First, we performed RNA microarray analysis hearts mice subjected sham surgery or aortic banding found that T-UCR uc.323 was decreased significantly in with banding-induced In vitro loss-...
Abstract Background The C 2 HEST score has been validated for predicting AF in the general population or post-stroke patients. We aimed to assess whether this risk could predict incident and other clinical outcomes heart failure with preserved ejection fraction (HFpEF) Methods A total of 2202 HFpEF patients without baseline TOPCAT trial were stratified by score. Cox proportional hazard model competing regression was used explore relationship between outcomes, including AF, stroke, all-cause...
KH 15D contains a circumbinary disk that is tilted relative to the orbital plane of central binary. The precession and motion binary together produce rich phenomena in photometric light curve. In this work, we present discovery preliminary analysis two objects resemble key features from Zwicky Transient Facility. These new objects, Bernhard-1 Bernhard-2, show large-amplitude ($>1.5\,$mag), long-duration (more than tens days), periodic dimming events. A one-sided screen model developed...
Giardia duodenalis is a ubiquitous flagellated protozoan, causing significant economic losses to animal husbandry and posing threats public health. China ranks the world's sixth largest major producer of donkeys, rearing approximately 2.6 million donkeys in 2019, but limited investigation G. prevalence has been conducted past, it yet be known whether Shanxi Province are infected with duodenalis. In present study, total 815 fecal samples collected from representative regions Province, North...
Introduction: Endometriosis, the most common gynecological disorder, is a challenging disease observed in 20% -40% of subfertile women.Material and Methods: 380 women were divided into four groups.Group A consisted 176 with pelvic endometriosis.Group B 125 who had previously undergone laparoscopic endometrioma cystectomy.Group C 38 recurrent endometriomas without aspiration before IVF-ET/ICSI.Group D 41 IVF-ET/ICSI.Results: Baseline FSH level (8.61 ± 3.42 mIU/mL) total dose Gn (2337.15±...
Aim: We aimed to examine the association between baseline mean platelet volume/platelet count ratio (MPR) and all-cause mortality in patients with infective endocarditis (IE). Patients & methods: This study analyzed 218 consecutive IE divided them into four groups based on MPR quartiles. used Kaplan–Meier survival curves determine cumulative Cox proportional hazards models investigate after hospital discharge. Results: showed a gradual increase risk from lowest quartile highest quartile....
Abstract Aims Coexisting of atrial fibrillation (AF) in patients with heart failure preserved ejection fraction (HFpEF) could increase the risk mortality. In this study, we aimed to assess values CHADS2, R2CHADS2, and CHA2DS2‐VASc scores for AF prediction HFpEF patients. Methods results We performed a retrospective analysis on symptomatic TOPCAT (Treatment Preserved Cardiac Function Heart Failure an Aldosterone Antagonist) trial. Associations incident without baseline ( n = 2202) were...
It remains controversial as to whether simvastatin has a beneficial effect on pulmonary artery hypertension. This study aimed explore the efficacy of haemodynamic changes, vascular remodelling and expression matrix metalloproteinase-1 -9 (MMP-1,9) in carotid artery–jugular vein (CA–JV) shunt hypertension (PAH) model rats. Thirty-six Sprague-Dawley rats were randomized into three groups: Control group, CA–JV Treatment group. A pre-tricuspid systemic-pulmonary from left common external jugular...
Heart failure with reduced ejection fraction (HFrEF) and heart preserved (HFpEF) had distinct haemodynamic characteristics in the setting of acute failure. The aim our study is to evaluate differential response aggressive diuresis HFrEF HFpEF.Patients Diuretic Optimization Strategies Evaluation trial left ventricular measurement were included (n = 300) classified into [left (LVEF) < 40%] 193) HFpEF (LVEF ≥ 40%) 107). Effect high-dose vs. low-dose furosemide strategy was compared separately...
Cardiac hypertrophy is a pathophysiological response to harmful stimuli. The continued presence of cardiac will ultimately develop into heart failure. mitochondrion the primary organelle energy production, and its dysfunction plays crucial role in progressive development failure from hypertrophy. Hispidulin, natural flavonoid, has been substantiated improve metabolism inhibit oxidative stress. However, how hispidulin regulates underlying mechanism remains unknown. We found that significantly...
Purpose: To study the accuracy of non-invasive chromosomal screening (NICS) results, in normal chromosomes and rearrangement groups to investigate whether using trophoblast cell biopsy along with NICS, choose embryos for transfer can improve clinical outcomes assisted pregnancy. Methods: We retrospectively analyzed 101 couples who underwent preimplantation genetic testing at our center from January 2019 June 2021 collected 492 blastocysts trophocyte (TE) biopsy. D3-5 blastocyst culture fluid...
ABSTRACT Objective In patients with heart failure preserved ejection fraction (HFpEF), whether living alone could contribute to a poor prognosis remains unknown. We sought investigate the association of clinical outcomes in HFpEF. Methods Symptomatic HFpEF follow-up 3.3 years (data collected from August 2006 June 2013) Treatment Preserved Cardiac Function Heart Failure an Aldosterone Antagonist trial were classified as and those others. The primary outcome was defined composite...