- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Reconstructive Facial Surgery Techniques
- Nutrition and Health in Aging
- Reconstructive Surgery and Microvascular Techniques
- Medical Imaging Techniques and Applications
- Oral and Maxillofacial Pathology
- Radiomics and Machine Learning in Medical Imaging
- Chromatin Remodeling and Cancer
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Tracheal and airway disorders
- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Otolaryngology and Infectious Diseases
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Respiratory and Cough-Related Research
- Salivary Gland Disorders and Functions
- Advances in Oncology and Radiotherapy
- Metastasis and carcinoma case studies
- MRI in cancer diagnosis
- Tumors and Oncological Cases
- Cleft Lip and Palate Research
University of Naples Federico II
2016-2021
Ospedale San Paolo
2021
Ospedale dei Pellegrini
2021
Federico II University Hospital
2015-2020
University of Campania "Luigi Vanvitelli"
2019-2020
The diffusion of laryngeal cancer cells in the perineural space is a parameter associated with negative prognosis, high loco-regional recurrence and low disease-free survival rates. spread tumor on sheath highlights histopathological clinically aggressive behavior this type tumor, which may extend proximally or distally nerve for >10 cm. Therefore, surgical resection margin generally insufficient to treat patients presenting invasion (PNI) surgery alone. In PNI, minor nerves are frequently...
Basaloid squamous cell carcinoma (BSCC) is a rare, aggressive and distinct variant of (SCC) the upper respiratory digestive tract. We have evaluated disease specific survival (DSS) overall (OS) through Kaplan-Meier method mortality risk univariate statistical analysis Cox in 42 cases BSCC other laryngeal SCC (LSCC) matched for both age sex. demonstrated that more tumor than LSCC as associated to higher nodal recurrence pathology (5 vs 2 patients, risk, OR 2.7), reduced (median 34 40 months,...
This study analysed the immunohistochemical expression of CAF-1/p60 protein in laryngeal cancers. assumes an independent discriminative and prognostic value neoplasms; presence this carcinoma situ compared with precancerous larynx infiltrating tumours. We assessed 30 cases moderate and/or severe dysplasia, squamous cell (LSCCs). increased significantly according to high index neoplastic cellular replication; therefore, was overexpressed cells its moderate-severe is correlated poorer...
Abstract Introduction In the present study, we have reviewed outcomes of patients with supracricoid partial laryngectomy (SCPL) in our institution. Our results show that SCPL is a well-tolerated procedure generally good functional for advanced laryngeal cancer. Objective We analyzed oncological and cohort 35 who had undergone SCPL, highlighted complications, identified overall disease-free survivals, demonstrating reconstructive guarantees safety reproducibility results, preserving functions...
Folate deficiency may be directly associated with carcinogenesis. supplementation reduce the risk of progression in a mucosa that is already genetically altered. The aim present study was to determine role folic acid treatment mild and moderate laryngeal dysplasia recurring after surgery. data obtained by laryngoscopy, measurement serum folate levels functional vocal assessment GIRBAS scale VHI questionnaire were compared patients who had received homogeneous group not undergone any therapy....
Laryngeal neuroendocrine carcinomas (LNECs) are rare and highly heterogeneous malignancies presenting a wide range of pathological clinical manifestations. Herein, we retrospectively characterize ten patients diagnosticated with LNEC, five which were defined as well-moderately differentiated carcinomas, that poorly according to the latest WHO classification. Clinical features analyzed compared between two subgroups together microRNA study evidenced peculiar signature likely related larynx...