A5107341426- Eosinophilic Disorders and Syndromes
- Genetic and rare skin diseases.
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Autoimmune and Inflammatory Disorders
- Dermatologic Treatments and Research
- Skin Diseases and Diabetes
- Medicine and Dermatology Studies History
- Nail Diseases and Treatments
- Dermatological and COVID-19 studies
- Systemic Lupus Erythematosus Research
- Vascular Tumors and Angiosarcomas
- Urticaria and Related Conditions
- Cancer and Skin Lesions
- Dermatological and Skeletal Disorders
- Systemic Sclerosis and Related Diseases
- Peripheral Neuropathies and Disorders
- Oral Health Pathology and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Dermatology and Skin Diseases
- Mast cells and histamine
- Streptococcal Infections and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Autoimmune and Inflammatory Disorders Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Hôpital Saint-Louis
2015-2024
Assistance Publique – Hôpitaux de Paris
2015-2024
Université Paris Cité
1990-2023
Centre Hospitalier Universitaire de Besançon
2023
Institut Pasteur
2022
Délégation Paris 7
2012-2021
Sorbonne Paris Cité
2020-2021
Société Française de Cardiologie
2018
Centre Georges François Leclerc
2017
Centre Hospitalier Universitaire de Clermont-Ferrand
2011-2013
Abstract The term ‘sclerosing diseases of the skin' comprises specific dermatological entities, which have fibrotic changes skin in common. These mostly manifest different clinical subtypes according to cutaneous and extracutaneous involvement can sometimes be difficult distinguish from each other. present guideline focuses on characteristic histopathological features, diagnostic scores serum autoantibodies most useful for differential diagnosis. In addition, current strategies first‐...
Hypocomplementemic urticarial vasculitis (HUV) is an uncommon of unknown etiology that rarely described in the literature. We undertook this study to analyze clinical spectrum and therapeutic management patients with HUV.We conducted a French nationwide retrospective included 57 chronic urticaria, histologic leukocytoclastic vasculitis, hypocomplementemia. assessed laboratory data evaluated patients' cutaneous immunologic responses therapy. treatment efficacy by measuring time...
The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fibrotic changes skin in common. These mostly manifest different clinical subtypes according to cutaneous and extracutaneous involvement can sometimes be difficult distinguish from each other. present guideline focuses on characteristic histopathological features, diagnostic scores serum autoantibodies most useful for differential diagnosis. In addition, current strategies first- advanced-line...
Abstract Background There are few population‐based studies assessing the prevalence of skin diseases. Objectives To estimate five chronic inflammatory diseases, i.e. atopic dermatitis (AD), psoriasis, alopecia areata (AA), vitiligo and hidradenitis suppurativa (HS) in France, using validated self‐diagnostic questionnaires. Methods Population‐based study a representative sample French general population aged more than 15 years sampling with replacement design. All participants were asked (ii)...
Abstract Introduction Adequate volume expansion (VE) in patients with evidence of hypoperfusion should be aimed not only at achieving an increase stroke (SV) and cardiac index (CI) but also improved tissue perfusion oxygenation. Our aim this study was to assess the dynamic changes muscle oxygen saturation (StO 2 ) during hypovolaemia response VE. Methods We conducted a prospective 42 fluid challenges undergoing major abdominal surgery hypovolaemia, defined as pulse pressure variation (PPV)...
Folliculitis decalvans (FD) is a chronic inflammatory disease of unknown aetiology. Although Staphylococcus aureus, frequently found on lesional skin, thought to play causal role, the importance its involvement remains controversial. To examine role S we compared superficial and subepidermal microbiota in 20 FD patients who had aureus skin healthy controls using culture techniques genomic identification, before after an anti-staphylococcal treatment; also screened for virulence factors. When...
Abstract Background Blau syndrome ( BS ) is a rare monogenic autoinflammatory disease caused by NOD 2 mutations. classically presents in early childhood as triad of granulomatous polyarthritis, uveitis and skin involvement. Joint ocular involvement have been characterized several cohort studies but only very little data are available on lesions. Objectives We aimed to provide detailed clinical microscopic analysis manifestations study whether they may contribute an diagnosis. Methods...
Introduction Leprosy reactions (LRs) are inflammatory responses observed in 30%-50% of people with leprosy. First-line treatment is glucocorticoids (GCs), often administered at high doses prolonged courses, resulting morbi-mortality. Methotrexate (MTX) an immunomodulating agent used to treat diseases and has excellent safety profile worldwide availability. In this study, we describe the efficacy, GCs-sparing effect MTX LRs. Methods We conducted a retrospective multicentric study France...
Some keloids show cystic cavities that give rise to acute inflammatory flares and oozing. These suppurative (SK) have rarely been systematically studied. We conducted a retrospective cohort study evaluate SK frequency its risk factors. also reviewed microbiological analyses as well the histological features of removed SKs.Between July 1, 2015, September 30, 2016, all adult patients attending specialized keloid clinic were asked participate. Clinical information results extracted from each...