- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Retinopathy of Prematurity Studies
- Ocular Oncology and Treatments
- Retinal Diseases and Treatments
- Cutaneous Melanoma Detection and Management
- Allergic Rhinitis and Sensitization
- Cancer Treatment and Pharmacology
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Neonatal Respiratory Health Research
- Child Abuse and Related Trauma
- Preterm Birth and Chorioamnionitis
- Optical Imaging and Spectroscopy Techniques
- Global Health and Surgery
- Travel-related health issues
- Kawasaki Disease and Coronary Complications
- Digital Marketing and Social Media
- Ophthalmology and Eye Disorders
- Coronary Artery Anomalies
- Sharing Economy and Platforms
University of Auckland
2016-2025
Auckland District Health Board
2018
Greenlane Clinical Centre
2018
University of Alabama at Birmingham
2011
The COVID-19 pandemic has sparked unprecedented public health and social measures (PHSM) by national local governments, including border restrictions, school closures, mandatory facemask use stay at home orders. Quantifying the effectiveness of these interventions in reducing disease transmission is key to rational policy making response current future pandemics. In order estimate interventions, detailed descriptions their timelines, scale scope are needed. Health Intervention Tracking for...
We investigated the relationship between corneal subbasal nerve (SBN) plexus density, sensitivity, and peripheral cardiac autonomic neuropathy in patients with type 1 diabetes mellitus.We recruited 53 mellitus 40 normal control participants. Corneal vivo confocal microscopy (IVCM) sensitivity testing were performed on one eye of each subject. Autonomic function was done an overall score obtained from a combination symptomatic score, clinical assessment, biothesiometry, conduction tests.The...
Purpose. To compare tear film metrics in patients with type 1 diabetes mellitus (DM) and healthy controls investigate the association between peripheral neuropathy ocular surface quality. Methods. Dry eye symptoms were quantified 53 DM 40 age-matched controls. Ocular examination included lipid layer thickness grading, stability quantity measurement, retinal photography. individuals additionally underwent a detailed assessment. Results. Neither mean age nor dry symptom scores differed...
The aim of this study was to analyze microstructural corneal changes following phacoemulsification cataract with intraocular lens insertion in diabetes mellitus (DM).Prospective consecutive patients undergoing insertion, over a period 6 months. Age, gender, serum glycosylated hemoglobin A1c levels, and effective time were recorded. Anterior segment optical coherence tomography vivo confocal microscopy performed preoperatively 1-month postoperatively. Subbasal nerve plexus (SBN) density,...
SIGNIFICANCE Tear film lipid layer interferometry is one of the most sensitive diagnostic markers for evaporative dry eye disease. However, dynamic structure breaks up and reforms rapidly during each blink cycle, it remains yet to be established whether there may significant intrasessional, diurnal, or day-to-day variability. PURPOSE This study aimed assess intrasession repeatability, diurnal intravisit intervisit reproducibility qualitative tear grading obtained from Keratograph 5M (Oculus...
The aim is to investigate ethnic variation, in presentation and biometric parameters, within the population undergoing cataract surgery Auckland.The design a retrospective study.Four thousand nine hundred thirty-one eyes of 3524 consecutive patients Auckland Public Hospital over 18 months were included study.Analysis preoperative medical records was performed.Age, gender, self-reported ethnicity, keratometry, anterior chamber depth, axial length intraocular lens (IOL) power data...
SIGNIFICANCE Dry eye is a frequently reported problem among computer users. Low relative humidity environments are recognized to exacerbate signs and symptoms of dry eye, yet common in offices operators. Desktop USB-powered humidifiers available commercially, but their efficacy for relief has not been established. PURPOSE This study aims evaluate the potential desktop humidifier improve tear-film parameters, ocular surface characteristics, subjective comfort METHODS Forty-four users were...
Purpose: The current study describes corneal nerve morphology using in vivo confocal microscopy (IVCM) patients with type 1 diabetes (T1D) who were followed up for 6 years, and it examines the relationship between parameters metabolic control of glucose peripheral neuropathy. Methods: Sixty-two participants (37 T1D 25 participants) assessed 2011 2017. Participants bilateral cataract surgery or controls developed excluded. All underwent HbA1c, IVCM, central sensitivity measurements at both...
Conjunctival melanoma (CM) is a rare and aggressive malignancy. Global studies demonstrate increased burden of disease in countries with high rates cutaneous melanoma. There are currently no reports on CM incidence, trends, or survival within Aotearoa-New Zealand (NZ), country the highest global melanoma, which this study aims to address.This was retrospective review using national cancer registry.Data histologically confirmed diagnosed between January 1, 2000, December 31, 2020, were...
To investigate the configuration of living human corneal subbasal nerve plexus in paired eyes normal subjects using vivo confocal microscopy.Laser scanning microscopy was performed on both corneas healthy subjects, and a grid fixation pattern facilitated examination consistent areas central to midperipheral cornea. Macromedia/Adobe Freehand 10 used manually arrange images into contiguous montages. The density overall patterns were analyzed.Both 6 (3 women 3 men, aged between 25 36 years)...
Abstract Background To develop and validate a deep learning-based approach to the fully-automated analysis of macaque corneal sub-basal nerves using in vivo confocal microscopy (IVCM). Methods IVCM was used collect 108 images from 35 macaques. 58 22 macaques were evaluate different convolutional neural network (CNN) architectures for automatic relative manual tracings. The remaining independently assess correlations inter-observer performance three readers. Results Correlation scores...
To investigate the epidemiologic, demographic, and basic clinical characteristics of individuals with keratoconus managed by optometrists in New Zealand (NZ)/Aotearoa.A prospective, longitudinal, nationwide, survey protocol was completed for every patient who underwent a consultation participating 2-year period. Data each included date birth, sex, self-reported ethnicity, new or previous diagnosis, uncorrected (UCVA) best-corrected visual acuity (BCVA), type refractive correction required to...
Magnetic resonance imaging (MRI) has demonstrated high levels of tissue contrast, accuracy and reproducibility in evaluating posterior uveal melanoma. Owing to smaller size, the role MRI detecting characterising iris melanoma not yet been explored. Aims: To develop a protocol image describe characteristics histopathological-confirmed An optimised protocol, using 3 T scanner 32-channel head coil, was developed tumours. A prospective, single-centre, 12-month study conducted on all patients...
Early detection of ocular abnormalities in newborn infants is essential for timely diagnosis and treatment. This study aimed to assess wide-field digital imaging universal eye screening (UNES) determine the prevalence abnormalities, including retinal haemorrhages, New Zealand.Prospective infants.A public hospital maternity ward a community birth centre Auckland, Zealand.A total 350 were enrolled UNES, those with weight <1250 g or gestational age <30 weeks excluded.Wide-field images external...
To assess the effects of panretinal photocoagulation (PRP) for diabetic retinopathy (DR) on human corneal subbasal nerve plexus (SBNP) and to investigate correlations between (SBN) density, sensitivity, peripheral neuropathy.Thirty-eight subjects with at least a 10-year history diabetes mellitus (DM) or DR were included. Subjects assigned PRP group (n = 19), having undergone treatment in one eye non-PRP no PRP. The Michigan Neuropathy Screening Instrument (MNSI) was administered enable...
This study aimed to investigate changes in visual acuity, corneal parameters, and topographic parameters after pterygium surgery.
Importance Intraocular pressure (IOP) is often reduced following cataract surgery. Postoperative changes in corneal stiffness are likely to be at least partly responsible for any reduction IOP measured with applanation tonometry. Background To determine the effect of surgery and incision size on biomechanics. Design Prospective randomized trial. Participants One hundred prospectively enrolled patients qualifying Methods were clear incisions a 2.20 or 2.85 mm keratome. Corneal Visualisation...