A5100415867- Protein Degradation and Inhibitors
- Chaos-based Image/Signal Encryption
- Peptidase Inhibition and Analysis
- Heat Transfer and Optimization
- Advanced Steganography and Watermarking Techniques
- Random lasers and scattering media
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Extracellular vesicles in disease
- Congenital Anomalies and Fetal Surgery
- Refrigeration and Air Conditioning Technologies
- Advanced Materials and Mechanics
- Pharmacological Effects of Natural Compounds
- Heat transfer and supercritical fluids
- Force Microscopy Techniques and Applications
- Bone Metabolism and Diseases
- Trace Elements in Health
- Ion channel regulation and function
- Dielectric materials and actuators
- Prenatal Screening and Diagnostics
- Histone Deacetylase Inhibitors Research
- Chromatin Remodeling and Cancer
- Heat Transfer and Boiling Studies
- Ubiquitin and proteasome pathways
- Ginseng Biological Effects and Applications
Zhengzhou University
2023-2024
Xi'an Polytechnic University
2024
West China Hospital of Sichuan University
2023
Sichuan University
2023
Shandong University
2019-2022
First Affiliated Hospital of Zhengzhou University
2018
Union Hospital
2016
Huazhong University of Science and Technology
2016
Beijing Children’s Hospital
2011
Abstract People who develop bladder cancer frequently succumb to the intractable disease. Current treatment strategies are limited presumably due underlying molecular complexity and insufficient comprehension. Therefore, exploration of new therapeutic targets in remains necessary. Here, we identify that bromodomain-4 protein (BRD4), an important epigenome reader bromodomain extraterminal domain (BET) family member, is a key upstream regulator enhancer zeste homologue 2 (EZH2), represents...
Ginsenoside Rb1 (Rb1) has been reported to have varieties of neuroprotective effects. This study aimed evaluate the effects on pentylenetetrazol (PTZ)-induced rat brain injury and Mg2+ free-induced neuron analyzed detailed molecular mechanisms in vivo vitro. Seizure duration latency were measured epilepsy kindled rat. The cognitive impairment was assessed by Morris water maze (MWM) test. Oxidative stress parameters, malondialdehyde (MDA) glutathione (GSH) 2-thiobarbituric acid methods...
The programmed cell death-ligand-1 (PD-L1) and bromodomain protein 4 (BRD4) are frequently overexpressed in cancer have even been shown to act synergistically. aim of this study was determine their potential oncogenic role .in tongue squamous carcinoma (TSCC). We detected significantly higher expression levels both PD-L1 BRD4 TSCC tissues compared normal (P ≤ .05). In addition, the high were associated with increased tumor lymphatic metastasis .05), staging .01), as well Genetic...
Printed circuit heat exchangers (PCHEs) have the characteristics of high temperature and pressure resistance, as well compact structure, so they are widely used in supercritical carbon dioxide (S-CO2) Brayton cycle. In order to fully study transfer process Z-type PCHE, a numerical model traditional PCHE was established accuracy verified. On this basis, new type spiral (S-ZPCHE) is proposed paper. The segmental design method compare changes under 5 different angles, it found that increasing...
Abstract Objective Emerging evidence suggests that glucose depletion (GD)‐induced cell death depends on system Xc − , a glutamate/cystine antiporter extensively studied in ferroptosis. However, the underlying mechanism remains debated. Our study confirmed correlation between and GD‐induced provided strategic treatment for oral squamous carcinoma (OSCC). Methods qPCR Western blotting were performed to detect changes xCT CD98 expression after withdrawal. Then, viability of OSCCs under...