A5069366632- Medical Imaging Techniques and Applications
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Radiation Detection and Scintillator Technologies
- Nuclear Physics and Applications
- Radiopharmaceutical Chemistry and Applications
- Atomic and Subatomic Physics Research
- Photoacoustic and Ultrasonic Imaging
- Ultrasound Imaging and Elastography
- Cancer, Hypoxia, and Metabolism
- Advanced MRI Techniques and Applications
- Amino Acid Enzymes and Metabolism
- Cardiac Imaging and Diagnostics
- Advanced Radiotherapy Techniques
- Optical Imaging and Spectroscopy Techniques
- Ultrasound and Hyperthermia Applications
- Crystallography and molecular interactions
- Boron Compounds in Chemistry
- Radiomics and Machine Learning in Medical Imaging
- Flow Measurement and Analysis
- Glioma Diagnosis and Treatment
- Radioactive Decay and Measurement Techniques
- Electrical and Bioimpedance Tomography
- Sports Performance and Training
- Genetics and Physical Performance
Tohoku University Hospital
2017-2023
Tohoku University
2012-2023
University of Toyama
2022-2023
Japan Radioisotope Association
2021-2023
Osaka University
2012-2021
Juntendo University
2019-2020
Tokyo University of Science
2017
Yamaguchi University
2016
Graduate School USA
2016
Japan Aerospace Exploration Agency
2012-2013
In the field of nuclear medicine, single photon emission tomography and positron are two most common techniques in molecular imaging, but available radioactive tracers have been limited either by energy range or difficulties production delivery. Thus, use a Compton camera, which features gamma-ray imaging arbitrary energies from few hundred keV to more than MeV, is eagerly awaited along with potential new never used current modalities. this paper, we developed an ultra-compact camera that...
Boron neutron capture therapy (BNCT) is a molecular radiation treatment based on the (10)B (n, α) (7)Li nuclear reaction in cancer cells, which delivery of by 4-borono-phenylalanine conjugated with fructose (BPA-fr) to cells critical importance. The PET tracer 4-borono-2-(18) F-fluoro-phenylalanine (FBPA) has been used predict accumulation BPA-fr before BNCT. However, because difference chemical structure between and FBPA dose administered (therapeutic dose) (tracer dose), predictive value...
Salinity stress can greatly reduce seed production because plants are especially sensitive to salt during their reproductive stage. Here, we show that the sodium ion transporter AtHKT1;1 is specifically expressed around phloem and xylem of stamen in Arabidopsis thaliana prevent a marked decrease caused by stress. The stamens mutant under overaccumulate Na + , limiting elongation resulting male sterility. Specifically restricting expression leads 1.5-fold increase yield upon Expanding...
Cell-sheet transplantation induces angiogenesis for chronic myocardial infarction (MI), though insufficient capillary maturation and paucity of arteriogenesis may limit its therapeutic effects. Omentum has been used clinically to promote revascularization healing ischemic tissues. We hypothesized that cell-sheet covered with an omentum-flap would effectively establish mature blood vessels improve coronary microcirculation physiology, enhancing the effects therapy. Rats were divided into four...
Abstract Pteris vittata is an arsenic (As) hyperaccumulator plant that accumulates a large amount of As into fronds and rhizomes (around 16,000 mg/kg in both after 16 weeks hydroponic cultivation with 30 mg/L arsenate). However, the sequence long-distance transport this unclear. In study, we used positron-emitting tracer imaging system (PETIS) for first time to obtain noninvasive serial images behavior living plants 74 As-labeled tracer. We found kept accumulating as P. , whereas was...
Six-coordinate tetracyanidonitridorhenium(V) and -technetium(V) with axial N-heteroaromatic ligands, (PPh4)2[MN(CN)4L] [M = Re, L 4-(dimethylamino)pyridine (dmap), 3,5-lutidine (lut), 4-picoline (pic), 4-phenylpyridine (ppy), pyridine (py), 3-benzoylpyridine (3bzpy), 4,4′-bipyridine (bpy), pyrazine (pz), 4-cyanopyridine (cpy), or 4-benzoylpyridine (4bzpy); M Tc, dmap, lut, pic, py, pz, cpy] were synthesized characterized. The crystal structures of 11 complexes determined by single-crystal...
Six-coordinate distorted octahedral tetracyanidonitridorhenium(V) and -technetium(V) complexes with a volatile organic compound (VOC) coordinating at the trans position of nitrido ligand, (PPh4)2[MN(CN)4L] (M = Re, L MeOH, EtOH, acetone, or MeCN; M Tc, MeOH), five-coordinate square-pyramidal tetracyanidonitrido without an axial (PPh4)2[MN(CN)4] Re Tc), were synthesized characterized. Single-crystal X-ray structural analysis was carried out for acetone; MeOH) (PPh4)2[ReN(CN)4]. All studied...
The purpose of this study was to establish a practical method estimate the absolute boron concentrations in tissues based on standardized uptake values (SUVs) after administration 4-borono-phenylalanine (BPA) using 4-borono-2-18F-fluoro-phenylalanine (18F-FBPA) PET.Rat xenograft models C6 glioma (n = 7, body weight 241 ± 28.0 g) were used for study. PET performed 60 min intravenous injection 18F-FBPA (30.5 0.7 MBq). After scanning, BPA-fructose (167.3 18.65 mg/kg) administered by slow same...
Potassium (K) is a major essential element in plant cells, and KUP/HAK/KT-type K+ transporters participate the absorption of into roots long-distance transport to above-ground parts. In Arabidopsis thaliana, KUP9 involved Cs+ roots. this study, we investigated function relation status plant. The expression was upregulated older leaves on K+-depleted medium, compared other 12 KUP genes KUP/HAK/KT family Arabidopsis. When grown low kup9 mutant had reduced chlorophyll content seedlings...
High-intensity focused ultrasound is a noninvasive treatment applied by externally irradiating to the body coagulate target tissue thermally. Recently, it has been proposed as for vascular occlusion replace conventional invasive treatments. Cavitation bubbles generated can accelerate effect of thermal coagulation. However, tissues surrounding may be damaged cavitation outside area. Conventional methods based on Doppler analysis only in time domain are not suitable monitoring blood flow...
Chapter 1.The "pseudofasciole", or zigzag line, found on the surface of body in some scutellids 44
Positron emission tomography (PET) studies using 15O-labeled CO2, O2, and CO have been used in humans to evaluate cerebral blood flow (CBF), the oxygen extraction fraction (OEF), metabolic rate of (CMRO2) volume (CBV), respectively. In preclinical studies, however, PET gases are not widely performed because technical difficulties associated with handling labeled a short half-life. The aims present study were scatter 3D-mode micro-PET for gas influence reconstruction algorithms on...
We report the development of a monolithic MPPC array, which consists 3 × mm2 elements arranged as 4 array manufactured by Hamamatsu applicable to next generation PET scanners. show that is suitable for time flight applications simple measurement using coincident back-to-back 511 keV gamma rays. demonstrated has much better timing resolution ∼ 600 ps than APD. coupled with Ce:LYSO and Pr:LuAG scintillator matrices gamma-ray detectors. The energy resolutions were evaluated 14% 662 gamma-rays...
Impulsive Raman excitation of C(60) by single or double pulses near-infrared wavelength λ = 1800 nm was investigated using a time-dependent adiabatic state approach combined with the density functional theory method. We confirmed that vibrational energy stored in active mode is maximized when T(p) ~ T(vib)/2 case pulse, where pulse length and T(vib) period mode. In selective can be achieved adjusting interval τ. The if τ chosen to equal an integer multiple it minimized half-integer T(vib)....
In order to establish a self-sufficient supply of 99mTc, we studied feasibilities produce its parent nucleus, 99Mo, using Japanese accelerators. The daughter is indispensable for medical diagnosis. 99Mo has so far been imported from abroad, which separated fission products generated in nuclear reactors enriched 235U fuel. We investigated 99mTc production possibilities based on the following three scenarios: (1) by (n, 2n) reaction spallation neutrons at J-PARC injector, LINAC; (2) (p, pn) Ep...